Glutamate dehydrogenase in brain mitochondria: Do lipid modifications and transient metabolon formation influence enzyme activity? (Q37902770)

25 August 2017

1 reference

title

Glutamate dehydrogenase in brain mitochondria: do lipid modifications and transient metabolon formation influence enzyme activity? (English)

1 reference

25 August 2017

Glutamate dehydrogenase in brain mitochondria: Do lipid modifications and transient metabolon formation influence enzyme activity? (English)

1 reference

https://api.crossref.org/works/10.1016/J.NEUINT.2011.07.003

7 December 2024

1 reference

1

Mary C. McKenna

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21771624

7 December 2024

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21771624

7 December 2024

publication date

13 July 2011

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full work available at URL

25 August 2017

https://europepmc.org/articles/pmc3459329?pdf=render

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Portable Document Format

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21771624

https://europepmc.org/articles/PMC3459329

7 December 2024

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HyperText Markup Language

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21771624

https://europepmc.org/articles/PMC3459329?pdf=render

7 December 2024

file format

Portable Document Format

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21771624

https://doi.org/10.1016/j.neuint.2011.07.003

7 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21771624

https://api.elsevier.com/content/article/PII:S0197018611002464?httpAccept=text/xml

7 December 2024

1 reference

https://api.crossref.org/works/10.1016/J.NEUINT.2011.07.003

https://api.elsevier.com/content/article/PII:S0197018611002464?httpAccept=text/plain

7 December 2024

1 reference

https://api.crossref.org/works/10.1016/J.NEUINT.2011.07.003

Neurochemistry International

7 December 2024

published in

1 reference

25 August 2017

59

1 reference

25 August 2017

4

1 reference

25 August 2017

525-533

1 reference

Mitochondrial Acetylation and Diseases of Aging

25 August 2017

1 reference

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The human GLUD2 glutamate dehydrogenase and its regulation in health and disease

6 September 2017

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Two genetic forms of hyperinsulinemic hypoglycemia caused by dysregulation of glutamate dehydrogenase

6 September 2017

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13N as a tracer for studying glutamate metabolism

6 September 2017

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The structure and allosteric regulation of glutamate dehydrogenase

6 September 2017

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Human GLUD2 glutamate dehydrogenase is expressed in neural and testicular supporting cells

6 September 2017

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Transgenic expression of Glud1 (glutamate dehydrogenase 1) in neurons: in vivo model of enhanced glutamate release, altered synaptic plasticity, and selective neuronal vulnerability

6 September 2017

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Branched-chain amino acid metabolon: interaction of glutamate dehydrogenase with the mitochondrial branched-chain aminotransferase (BCATm)

6 September 2017

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6 September 2017

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Human GLUD1 and GLUD2 glutamate dehydrogenase localize to mitochondria and endoplasmic reticulum.

6 September 2017

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The human GLUD2 glutamate dehydrogenase: localization and functional aspects

6 September 2017

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Untangling the glutamate dehydrogenase allosteric nightmare

6 September 2017

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6 September 2017

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HTF9C gene of 22q11.21 region associates with schizophrenia having deficit-sustained attention

6 September 2017

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6 September 2017

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SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

6 September 2017

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6 September 2017

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Central nervous system hyperexcitability associated with glutamate dehydrogenase gain of function mutations

6 September 2017

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Molecular basis of human glutamate dehydrogenase regulation under changing energy demands

6 September 2017

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Branched-chain amino acids and neurotransmitter metabolism: Expression of cytosolic branched-chain aminotransferase (BCATc) in the cerebellum and hippocampus

6 September 2017

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Hyperinsulinism/hyperammonemia syndrome: insights into the regulatory role of glutamate dehydrogenase in ammonia metabolism

6 September 2017

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Study of structure-function relationships in human glutamate dehydrogenases reveals novel molecular mechanisms for the regulation of the nerve tissue-specific (GLUD2) isoenzyme

6 September 2017

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Conformational change in aspartate aminotransferase on substrate binding induces strain in the catalytic group and enhances catalysis

6 September 2017

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Diffusion of tricarboxylic acid cycle enzymes in the mitochondrial matrix in vivo. Evidence for restricted mobility of a multienzyme complex

6 September 2017

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Ketogenic diet, amino acid metabolism, and seizure control

6 September 2017

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Regulation of human glutamate dehydrogenases: implications for glutamate, ammonia and energy metabolism in brain.

6 September 2017

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Structure and function of branched chain aminotransferases

6 September 2017

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Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation

6 September 2017

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Nerve tissue-specific (GLUD2) and housekeeping (GLUD1) human glutamate dehydrogenases are regulated by distinct allosteric mechanisms: implications for biologic function

6 September 2017

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Differential distribution of the enzymes glutamate dehydrogenase and aspartate aminotransferase in cortical synaptic mitochondria contributes to metabolic compartmentation in cortical synaptic terminals

6 September 2017

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Dynamics and environment of mitochondrial water as detected by 1H NMR.

6 September 2017

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The reaction catalyzed by Escherichia coli aspartate aminotransferase has multiple partially rate-determining steps, while that catalyzed by the Y225F mutant is dominated by ketimine hydrolysis

6 September 2017

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Demonstration of physical interactions between consecutive enzymes of the citric acid cycle and of the aspartate-malate shuttle. A study involving fumarase, malate dehydrogenase, citrate synthesis and aspartate aminotransferase

6 September 2017

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6 September 2017

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Abnormal Glutamate Metabolism in an Adult-Onset Degenerative Neurological Disorder

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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23 June 2018

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23 June 2018

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23 June 2018

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23 June 2018

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A simulation study of brain compartments. Metabolism of glutamate and related substances in mouse brain

23 June 2018

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Regulation of glutamate dehydrogenase by Mg2 and magnification of leucine activation by Mg2 .

23 June 2018

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The metabolism of malate by cultured rat brain astrocytes

23 June 2018

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23 June 2018

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Aspartate aminotransferase, malate dehydrogenase, and pyruvate carboxylase activities in rat cerebral synaptic and nonsynaptic mitochondria: effects of in vitro treatment with ammonia, hyperammonemia and hepatic encephalopathy

23 June 2018

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Immunocytochemical localization of mitochondrial malate dehydrogenase in primary cultures of rat astrocytes and oligodendrocytes

23 June 2018

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Effects of acute hepatic encephalopathy and in vitro treatment with ammonia on glutamate oxidation in bulk-isolated astrocytes and mitochondria of the rat brain

23 June 2018

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Glutamate dehydrogenase reaction as a source of glutamic acid in synaptosomes

23 June 2018

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Effect of potassium and N-methyl-D-aspartate on the aspartate aminotransferase activity in cultured cerebellar granule cells

23 June 2018

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23 June 2018

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Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways

23 June 2018

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Interplay of palmitoylation and phosphorylation in the trafficking and localization of phosphodiesterase 10A: implications for the treatment of schizophrenia.

1 September 2018

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Neurological aspects of hyperinsulinism-hyperammonaemia syndrome

1 September 2018

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Among the branched-chain amino acids, only valine metabolism is up-regulated in astrocytes during glutamate exposure.

1 September 2018

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Differential glutamate dehydrogenase (GDH) activity profile in patients with temporal lobe epilepsy

1 September 2018

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Aspartate aminotransferase in synaptic and nonsynaptic mitochondria: differential effect of compounds that influence transient hetero-enzyme complex (metabolon) formation

1 September 2018

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Response of brain amino acid metabolism to ketosis

1 September 2018

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GABA alters the metabolic fate of [U-13C]glutamate in cultured cortical astrocytes

1 September 2018

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Activity of the lactate-alanine shuttle is independent of glutamate-glutamine cycle activity in cerebellar neuronal-astrocytic cultures.

1 September 2018

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Whole-brain glutamate metabolism evaluated by steady-state kinetics using a double-isotope procedure: effects of gabapentin

1 September 2018

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Developmental switch in brain nutrient transporter expression in the rat.

1 September 2018

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SUBCELLULAR DISTRIBUTION OF THE ENZYMES OF THE GLUTAMIC ACID, GLUTAMINE AND γ‐AMINOBUTYRIC ACID CYCLES IN RAT BRAIN*

1 September 2018

1 reference

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Metabolic compartmentation in cortical synaptosomes: influence of glucose and preferential incorporation of endogenous glutamate into GABA.

1 September 2018

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Multiple compartments with different metabolic characteristics are involved in biosynthesis of intracellular and released glutamine and citrate in astrocytes

1 September 2018

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Function of leucine in excitatory neurotransmitter metabolism in the central nervous system

1 September 2018

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Synthesis of vesicular GABA from glutamine involves TCA cycle metabolism in neocortical neurons

1 September 2018

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Mitochondrial citrate synthase is immobilized in vivo

1 September 2018

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Comparison of lactate and glucose metabolism in cultured neocortical neurons and astrocytes using 13C-NMR spectroscopy

1 September 2018

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Mitochondrial heterogeneity in the brain at the cellular level

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459329

Trafficking between glia and neurons of TCA cycle intermediates and related metabolites

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459329

Glutamate transport and metabolism in astrocytes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459329

Exogenous glutamate concentration regulates the metabolic fate of glutamate in astrocytes.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459329

Regulation of malate dehydrogenases from neonatal, adolescent, and mature rat brain.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459329

Direct demonstration by [13C]NMR spectroscopy that glutamine from astrocytes is a precursor for GABA synthesis in neurons

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459329

NMR spectroscopic studies of 13C acetate and 13C glucose metabolism in neocortical astrocytes: evidence for mitochondrial heterogeneity

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459329

Regulation of energy metabolism in synaptic terminals and cultured rat brain astrocytes: differences revealed using aminooxyacetate

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459329

Differential effects of ammonia and beta-methylene-DL-aspartate on metabolism of glutamate and related amino acids by astrocytes and neurons in primary culture

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459329

Complexes between mitochondrial enzymes and either citrate synthase or glutamate dehydrogenase

1 September 2018

1 reference

12 December 2020

Neuronal glutamine utilization: pathways of nitrogen transfer studied with [15N]glutamine

1 reference

12 December 2020

Acidosis and astrocyte amino acid metabolism

1 reference

12 December 2020

Quantitative ultrastructural localization of glutamate dehydrogenase in the rat cerebellar cortex

1 reference

12 December 2020

Astrocyte leucine metabolism: significance of branched-chain amino acid transamination

1 reference

12 December 2020

Lactate formation from [U-13C]aspartate in cultured astrocytes: compartmentation of pyruvate metabolism

1 reference

12 December 2020

A possible role of alanine for ammonia transfer between astrocytes and glutamatergic neurons

1 reference

12 December 2020

New insights into the compartmentation of glutamate and glutamine in cultured rat brain astrocytes

1 reference

12 December 2020

Interactions between carbamyl phosphate synthase-I-mitochondrial aspartate aminotransferase and palmitoyl-CoA

1 reference

12 December 2020

Postnatal development of glutamate metabolizing enzymes in hippocampus from mice

1 reference

12 December 2020

Binding of citrate synthase and malate dehydrogenase to mitochondrial inner membranes: tissue distribution and metabolite effects

1 reference

12 December 2020

Interactions between pyruvate carboxylase and other mitochondrial enzymes

1 reference

12 December 2020

Regulation of mitochondrial and cytosolic malic enzymes from cultured rat brain astrocytes

1 reference

12 December 2020

Interactions among mitochondrial aspartate aminotransferase, malate dehydrogenase, and the inner mitochondrial membrane from heart, hepatoma, and liver

1 reference

12 December 2020

Monocarboxylic acid transporters, MCT1 and MCT2, in cortical astrocytes in vitro and in vivo

1 reference

12 December 2020

Kinetic advantages of hetero-enzyme complexes with glutamate dehydrogenase and the alpha-ketoglutarate dehydrogenase complex

1 reference

12 December 2020

A novel branched-chain amino acid metabolon. Protein-protein interactions in a supramolecular complex

1 reference

12 December 2020

Energy metabolism in cortical synaptic terminals from weanling and mature rat brain: evidence for multiple compartments of tricarboxylic acid cycle activity

1 reference

12 December 2020

Quantitative ultrastructural localization of glutamate dehydrogenase in the rat cerebellar cortex

1 reference

12 December 2020

Interaction between citrate synthase and mitochondrial malate dehydrogenase in the presence of polyethylene glycol

1 reference

12 December 2020

Immunocytochemical examination of neural rat and mouse primary cultures using monoclonal antibodies raised against pyruvate carboxylase

1 reference

12 December 2020

Mitochondrial malic enzyme activity is much higher in mitochondria from cortical synaptic terminals compared with mitochondria from primary cultures of cortical neurons or cerebellar granule cells

1 reference

12 December 2020

Glutamate-malate metabolism in liver mitochondria. A model constructed on the basis of mitochondrial levels of enzymes, specificity, dissociation constants, and stoichiometry of hetero-enzyme complexes

1 reference

12 December 2020

Evaluation of the importance of transamination versus deamination in astrocytic metabolism of [U-13C]glutamate

1 reference

12 December 2020

Glutamate and glutamine metabolism in cultured GABAergic neurons studied by 13C NMR spectroscopy may indicate compartmentation and mitochondrial heterogeneity

1 reference

12 December 2020

Energy metabolism of the brain

series ordinal

64

1 reference

https://api.crossref.org/works/10.1016/J.NEUINT.2011.07.003

7 December 2024

Identifiers

1 reference

25 August 2017

1 reference

25 August 2017

1 reference