The rediscovery of uromodulin (Tamm-Horsfall protein): from tubulointerstitial nephropathy to chronic kidney disease. (Q37886655)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21654721 AND SRC:MED&resulttype=core&format=json

3 February 2020

review article

1 reference

title

The rediscovery of uromodulin (Tamm-Horsfall protein): from tubulointerstitial nephropathy to chronic kidney disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21654721 AND SRC:MED&resulttype=core&format=json

3 February 2020

0 references

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21654721 AND SRC:MED&resulttype=core&format=json

3 February 2020

Luca Rampoldi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21654721 AND SRC:MED&resulttype=core&format=json

3 February 2020

Antonio Amoroso

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21654721 AND SRC:MED&resulttype=core&format=json

3 February 2020

author name string

Francesco Scolari

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21654721 AND SRC:MED&resulttype=core&format=json

3 February 2020

Olivier Devuyst

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21654721 AND SRC:MED&resulttype=core&format=json

3 February 2020

language of work or name

English

0 references

publication date

8 June 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21654721 AND SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21654721 AND SRC:MED&resulttype=core&format=json

3 February 2020

volume

80

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21654721 AND SRC:MED&resulttype=core&format=json

3 February 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21654721 AND SRC:MED&resulttype=core&format=json

3 February 2020

page(s)

338-347

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21654721 AND SRC:MED&resulttype=core&format=json

Tamm-Horsfall protein--uromodulin (1950-1990).

3 February 2020

cites work

1 reference

7 January 2021

Uromodulin: a unique 85-kilodalton immunosuppressive glycoprotein isolated from urine of pregnant women

1 reference

7 January 2021

Identification of human uromodulin as the Tamm-Horsfall urinary glycoprotein

1 reference

7 January 2021

Biosynthesis and oligosaccharide processing of human Tamm-Horsfall glycoprotein permanently expressed in HeLa cells

1 reference

7 January 2021

Pregnancy-associated changes in the glycosylation of tamm-horsfall glycoprotein. Expression of sialyl Lewis(x) sequences on core 2 type O-glycans derived from uromodulin.

1 reference

7 January 2021

The ZP domain is a conserved module for polymerization of extracellular proteins

1 reference

7 January 2021

Uromucoid (Tamm-Horsfall glycoprotein) forms different polymeric arrangements on a filter surface under different physicochemical conditions

1 reference

7 January 2021

Tamm-Horsfall protein-mRNA synthesis is localized to the thick ascending limb of Henle's loop in rat kidney

1 reference

7 January 2021

Ultrastructural localization of Tamm-Horsfall glycoprotein (THP) in rat kidney as revealed by protein A-gold immunocytochemistry

1 reference

7 January 2021

Ultrastructural localization of Tamm—Horsfall protein in human kidney using immunogold electron microscopy

1 reference

7 January 2021

Membrane targeting and secretion of mutant uromodulin in familial juvenile hyperuricemic nephropathy

1 reference

7 January 2021

Gene expression profiles in developing nephrons using Lim1 metanephric mesenchyme-specific conditional mutant mice

1 reference

7 January 2021

Tamm-Horsfall protein as a marker of tubular maturation

1 reference

7 January 2021

A panoramic view of gene expression in the human kidney

1 reference

7 January 2021

The turnover rate of rabbit urinary Tamm-Horsfall glycoprotein

1 reference

7 January 2021

Tamm-Horsfall glycoprotein: biology and clinical relevance

1 reference

7 January 2021

Urinary uromodulin carries an intact ZP domain generated by a conserved C-terminal proteolytic cleavage

1 reference

7 January 2021

Analysis of uromodulin polymerization provides new insights into the mechanisms regulating ZP domain-mediated protein assembly

1 reference

7 January 2021

A duplicated motif controls assembly of zona pellucida domain proteins

1 reference

7 January 2021

Identification of a unique urinary biomarker profile in patients with autosomal dominant polycystic kidney disease

1 reference

7 January 2021

The pancreatic zymogen granule membrane protein, GP2, binds Escherichia coli Type 1 fimbriae

1 reference

7 January 2021

Distribution of immunoreactive Tamm-Horsfall protein in various species in the vertebrate classes

1 reference

7 January 2021

Dietary salt regulates expression of Tamm-Horsfall glycoprotein in rats

1 reference

7 January 2021

Renal effects of Tamm-Horsfall protein (uromodulin) deficiency in mice

1 reference

7 January 2021

Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication

1 reference

7 January 2021

Ablation of the Tamm-Horsfall protein gene increases susceptibility of mice to bladder colonization by type 1-fimbriated Escherichia coli.

1 reference

7 January 2021

Tamm-Horsfall protein binds to type 1 fimbriated Escherichia coli and prevents E. coli from binding to uroplakin Ia and Ib receptors

1 reference

7 January 2021

Effects of Tamm-Horsfall protein and albumin on the inhibition of free radicals

1 reference

7 January 2021

Expression of Tamm‐Horsfall protein in stone‐forming rat models

1 reference

7 January 2021

Tamm-Horsfall protein is a critical renal defense factor protecting against calcium oxalate crystal formation

1 reference

7 January 2021

Progressive renal papillary calcification and ureteral stone formation in mice deficient for Tamm-Horsfall protein

1 reference

7 January 2021

Renal calcinosis and stone formation in mice lacking osteopontin, Tamm-Horsfall protein, or both

1 reference

7 January 2021

Tamm-Horsfall glycoprotein binds IgG with high affinity

1 reference

7 January 2021

Binding of Tamm-Horsfall protein to complement 1q measured by ELISA and resonant mirror biosensor techniques under various ionic-strength conditions

1 reference

7 January 2021

Uromodulin (Tamm-Horsfall glycoprotein): a renal ligand for lymphokines

1 reference

7 January 2021

Uromodulin facilitates neutrophil migration across renal epithelial monolayers

1 reference

7 January 2021

Tamm-Horsfall glycoprotein links innate immune cell activation with adaptive immunity via a Toll-like receptor-4-dependent mechanism.

1 reference

7 January 2021

Tubulointerstitial immune complex nephritis in rats immunized with Tamm-Horsfall protein

1 reference

7 January 2021

Tamm-Horsfall protein: a multilayered defence molecule against urinary tract infection

1 reference

7 January 2021

Tamm-Horsfall protein protects the kidney from ischemic injury by decreasing inflammation and altering TLR4 expression

1 reference

7 January 2021

Mutations of the UMOD gene are responsible for medullary cystic kidney disease 2 and familial juvenile hyperuricaemic nephropathy

1 reference

7 January 2021

Familial juvenile hyperuricaemic nephropathy

1 reference

7 January 2021

A cluster of mutations in the UMOD gene causes familial juvenile hyperuricemic nephropathy with abnormal expression of uromodulin

1 reference

7 January 2021

Allelism of MCKD, FJHN and GCKD caused by impairment of uromodulin export dynamics

1 reference

7 January 2021

Uromodulin storage disease

1 reference

7 January 2021

Autosomal dominant medullary cystic disease: a disorder with variable clinical pictures and exclusion of linkage with the NPH1 locus

1 reference

7 January 2021

Uromodulin-associated kidney disease

1 reference

7 January 2021

Apoptosis of tubular epithelial cells in familial juvenile gouty nephropathy

1 reference

7 January 2021

Outcome of kidney transplantation in familial juvenile hyperuricaemic nephropathy

1 reference

7 January 2021

A novel pattern of mutation in uromodulin disorders: autosomal dominant medullary cystic kidney disease type 2, familial juvenile hyperuricemic nephropathy, and autosomal dominant glomerulocystic kidney disease

1 reference

7 January 2021

Homozygosity for uromodulin disorders: FJHN and MCKD-type 2.

1 reference

7 January 2021

Clinico-pathologic findings in medullary cystic kidney disease type 2.

1 reference

7 January 2021

Alterations of uromodulin biology: a common denominator of the genetically heterogeneous FJHN/MCKD syndrome.

1 reference

7 January 2021

A transgenic mouse model for uromodulin-associated kidney diseases shows specific tubulo-interstitial damage, urinary concentrating defect and renal failure.

1 reference

7 January 2021

Uromodulin storage diseases: clinical aspects and mechanisms

1 reference

7 January 2021

Mutations in the uromodulin gene decrease urinary excretion of Tamm-Horsfall protein

1 reference

7 January 2021

Atypical familial juvenile hyperuricemic nephropathy associated with a hepatocyte nuclear factor-1beta gene mutation

1 reference

7 January 2021

Dominant renin gene mutations associated with early-onset hyperuricemia, anemia, and chronic kidney failure

1 reference

7 January 2021

Chromosome 1 localization of a gene for autosomal dominant medullary cystic kidney disease

1 reference

7 January 2021

Genome-wide study of familial juvenile hyperuricaemic (gouty) nephropathy (FJHN) indicates a new locus, FJHN3, linked to chromosome 2p22.1-p21

1 reference

7 January 2021

Functional consequences of a novel uromodulin mutation in a family with familial juvenile hyperuricaemic nephropathy

1 reference

7 January 2021

Uromodulin mutations causing familial juvenile hyperuricaemic nephropathy lead to protein maturation defects and retention in the endoplasmic reticulum

1 reference

7 January 2021

A case of familial juvenile hyperuricemic nephropathy with novel uromodulin gene mutation, a novel heterozygous missense mutation in Korea

1 reference

7 January 2021

Defective intracellular trafficking of uromodulin mutant isoforms

1 reference

7 January 2021

Mutant tamm-horsfall glycoprotein accumulation in endoplasmic reticulum induces apoptosis reversed by colchicine and sodium 4-phenylbutyrate

1 reference

7 January 2021

Tamm-Horsfall protein acts as a general host-defense factor against bacterial cystitis

1 reference

7 January 2021

Production and characterization of transgenic mice harboring mutant human UMOD gene

1 reference

7 January 2021

Novel missense mutation of uromodulin in mice causes renal dysfunction with alterations in urea handling, energy, and bone metabolism

1 reference

7 January 2021

Evidence for a role of uromodulin in chronic kidney disease progression.

1 reference

7 January 2021

Uromodulin is expressed in renal primary cilia and UMOD mutations result in decreased ciliary uromodulin expression

1 reference

7 January 2021

A mitotic transcriptional switch in polycystic kidney disease

1 reference

7 January 2021

Uromodulin Biology and Pathophysiology – An Update

1 reference

7 January 2021

Abnormal expression and processing of uromodulin in Fabry disease reflects tubular cell storage alteration and is reversible by enzyme replacement therapy.

1 reference

7 January 2021

Genome-Wide Association Studies in Nephrology Research

1 reference

7 January 2021

Multiple loci associated with indices of renal function and chronic kidney disease

1 reference

7 January 2021

New loci associated with kidney function and chronic kidney disease

1 reference

7 January 2021

Association of variants at UMOD with chronic kidney disease and kidney stones-role of age and comorbid diseases

1 reference

7 January 2021

A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level

1 reference

7 January 2021

Genetic loci influencing kidney function and chronic kidney disease

1 reference

7 January 2021

A haplotype map of the human genome

1 reference

7 January 2021

Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension

1 reference

7 January 2021

Uromodulin levels associate with a common UMOD variant and risk for incident CKD.

1 reference

7 January 2021

Uromodulin concentrations are not associated with incident CKD among persons with coronary artery disease

1 reference

7 January 2021

Renal expression of parvalbumin is critical for NaCl handling and response to diuretics

1 reference

7 January 2021

Insights into egg coat assembly and egg-sperm interaction from the X-ray structure of full-length ZP3

1 reference

7 January 2021