Autophagy as a target for anticancer therapy (Q37876679)

24 August 2017

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title

Autophagy as a target for anticancer therapy (English)

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24 August 2017

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4

Razelle Kurzrock

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24 August 2017

1

Filip Janku

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24 August 2017

David J McConkey

2

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24 August 2017

David S Hong

series ordinal

3

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24 August 2017

language of work or name

English

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publication date

17 May 2011

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Nature Reviews Clinical Oncology

24 August 2017

published in

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24 August 2017

volume

8

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24 August 2017

issue

9

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24 August 2017

page(s)

528-539

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Autophagy: process and function

24 August 2017

cites work

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Autophagy in cutaneous malignant melanoma

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31 March 2020

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Delta-24-RGD in combination with RAD001 induces enhanced anti-glioma effect via autophagic cell death

31 March 2020

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Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors.

31 March 2020

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Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells

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Temsirolimus downregulates p21 without altering cyclin D1 expression and induces autophagy and synergizes with vorinostat in mantle cell lymphoma

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The development of proteasome inhibitors as anticancer drugs

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Oncogenic transformation confers a selective susceptibility to the combined suppression of the proteasome and autophagy

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The anticancer drug imatinib induces cellular autophagy.

31 March 2020

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Imatinib interferes with survival of multi drug resistant Kaposi's sarcoma cells.

31 March 2020

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Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST).

31 March 2020

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Dasatinib-induced autophagy is enhanced in combination with temozolomide in glioma

31 March 2020

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Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells

31 March 2020

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Autophagy and autophagic cell death are next targets for elimination of the resistance to tyrosine kinase inhibitors

31 March 2020

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BCL-2 family inhibitors enhance histone deacetylase inhibitor and sorafenib lethality via autophagy and overcome blockade of the extrinsic pathway to facilitate killing

31 March 2020

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Apoptotic and autophagic cell death induced by histone deacetylase inhibitors

31 March 2020

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The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy

31 March 2020

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Involvement of macroautophagy in the caspase-independent killing of Burkitt lymphoma cell lines by rituximab

31 March 2020

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Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy

31 March 2020

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A role for macroautophagy in protection against 4-hydroxytamoxifen-induced cell death and the development of antiestrogen resistance

31 March 2020

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Recent advances in understanding the antineoplastic mechanisms of farnesyltransferase inhibitors

31 March 2020

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Autophagy induced by farnesyltransferase inhibitors in cancer cells

31 March 2020

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Inhibition of poly(ADP-ribose) polymerase enhances cell death and improves tumor growth delay in irradiated lung cancer models

31 March 2020

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PARP-1 is involved in autophagy induced by DNA damage.

31 March 2020

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Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death.

31 March 2020

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Potentiation of radiation sensitivity in breast tumor cells by the vitamin D3 analogue, EB 1089, through promotion of autophagy and interference with proliferative recovery

31 March 2020

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Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2.

31 March 2020

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Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3.

31 March 2020

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Arsenic trioxide induces not only apoptosis but also autophagic cell death in leukemia cell lines via up-regulation of Beclin-1.

31 March 2020

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Resveratrol induces growth inhibition and apoptosis in metastatic breast cancer cells via de novo ceramide signaling

31 March 2020

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Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells

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The prosurvival role of autophagy in Resveratrol-induced cytotoxicity in human U251 glioma cells

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Targeting tumor metabolism with 2-deoxyglucose in patients with castrate-resistant prostate cancer and advanced malignancies

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Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages

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Comparison of different autophagic vacuoles with regard to ultrastructure, enzymatic composition, and degradation capacity--formation of crinosomes

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Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

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Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance

31 March 2020

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Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

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Identifiers

DOI

1 reference

24 August 2017

1 reference