Do bacterial genotoxins contribute to chronic inflammation, genomic instability and tumor progression? (Q37876491)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21585655 AND SRC:MED&resulttype=core&format=json

1 February 2020

review article

1 reference

title

Do bacterial genotoxins contribute to chronic inflammation, genomic instability and tumor progression? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21585655 AND SRC:MED&resulttype=core&format=json

1 February 2020

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21585655 AND SRC:MED&resulttype=core&format=json

1 February 2020

Teresa Frisan

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21585655 AND SRC:MED&resulttype=core&format=json

1 February 2020

author name string

Lina Guerra

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21585655 AND SRC:MED&resulttype=core&format=json

1 February 2020

language of work or name

English

0 references

publication date

17 May 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21585655 AND SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21585655 AND SRC:MED&resulttype=core&format=json

1 February 2020

volume

278

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21585655 AND SRC:MED&resulttype=core&format=json

1 February 2020

issue

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21585655 AND SRC:MED&resulttype=core&format=json

1 February 2020

page(s)

4577-4588

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21585655 AND SRC:MED&resulttype=core&format=json

The role of bacterial pathogens in cancer

1 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

The contribution of cytolethal distending toxin to bacterial pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

CdtA, CdtB, and CdtC form a tripartite complex that is required for cytolethal distending toxin activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Assembly and function of a bacterial genotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Nuclear localization of the Escherichia coli cytolethal distending toxin CdtB subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Campylobacter jejuni cytolethal distending toxin promotes DNA repair responses in normal human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Carbohydrate-binding specificity of the Escherichia coli cytolethal distending toxin CdtA-II and CdtC-II subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

DNase I homologous residues in CdtB are critical for cytolethal distending toxin-mediated cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

A bacterial toxin that controls cell cycle progression as a deoxyribonuclease I-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Cytolethal distending toxin demonstrates genotoxic activity in a yeast model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Cellular internalization of cytolethal distending toxin: a new end to a known pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

A novel mode of action for a microbial-derived immunotoxin: the cytolethal distending toxin subunit B exhibits phosphatidylinositol 3,4,5-triphosphate phosphatase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Cytolethal distending toxin from Aggregatibacter actinomycetemcomitans induces DNA damage, S/G2 cell cycle arrest, and caspase- independent death in a Saccharomyces cerevisiae model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Aggregatibacter actinomycetemcomitans cytolethal distending toxin induces apoptosis in nonproliferating macrophages by a phosphatase-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Salmonella typhi encodes a functional cytolethal distending toxin that is delivered into host cells by a bacterial-internalization pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Delivery of a Salmonella Typhi exotoxin from a host intracellular compartment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Cholesterol-rich membrane microdomains mediate cell cycle arrest induced by Actinobacillus actinomycetemcomitans cytolethal-distending toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Haploid genetic screens in human cells identify host factors used by pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Involvement of ganglioside GM3 in G(2)/M cell cycle arrest of human monocytic cells induced by Actinobacillus actinomycetemcomitans cytolethal distending toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Cytolethal distending toxin family members are differentially affected by alterations in host glycans and membrane cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Cellular internalization of cytolethal distending toxin from Haemophilus ducreyi

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

A novel mode of translocation for cytolethal distending toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

An N-terminal segment of the active component of the bacterial genotoxin cytolethal distending toxin B (CDTB) directs CDTB into the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

The cytolethal distending toxin family

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Escherichia coli induces DNA double-strand breaks in eukaryotic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Genetic structure and distribution of the colibactin genomic island among members of the family Enterobacteriaceae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Expression analysis of the colibactin gene cluster coding for a novel polyketide in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

The DNA Damage Response: Making It Safe to Play with Knives

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

The multifaceted mismatch-repair system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

DNA repair in mammalian cells : Nucleotide excision repair: variations on versatility

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Collaboration and competition between DNA double‐strand break repair pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

The MRE11 complex: starting from the ends.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Genomic instability--an evolving hallmark of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

The chromosomal instability pathway in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

The biology of the cytolethal distending toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

The Haemophilus ducreyi cytolethal distending toxin induces DNA double-strand breaks and promotes ATM-dependent activation of RhoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

The Haemophilus ducreyi cytolethal distending toxin induces cell cycle arrest and apoptosis via the DNA damage checkpoint pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

The Haemophilus ducreyi cytolethal distending toxin activates sensors of DNA damage and repair complexes in proliferating and non-proliferating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Delivery of cytolethal distending toxin B induces cell cycle arrest and apoptosis in gingival squamous cell carcinoma in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

p53-independent expression of p21(CIP1/WAF1) in plasmacytic cells during G(2) cell cycle arrest induced by Actinobacillus actinomycetemcomitans cytolethal distending toxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

The bacterial cytolethal distending toxin (CDT) triggers a G2 cell cycle checkpoint in mammalian cells without preliminary induction of DNA strand breaks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Myc is required for activation of the ATM-dependent checkpoints in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Bacterial intoxication evokes cellular senescence with persistent DNA damage and cytokine signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Genome-wide analysis of cellular response to bacterial genotoxin CdtB in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Cell-cycle checkpoints and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

A bacterial cytotoxin identifies the RhoA exchange factor Net1 as a key effector in the response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Immunity, Inflammation, and Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

NF-kappaB functions as a tumour promoter in inflammation-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Helicobacter pylori: gastric cancer and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Chronic Helicobacter pylori infections induce gastric mutations in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Gastroenteritis in NF-kappaB-deficient mice is produced with wild-type Camplyobacter jejuni but not with C. jejuni lacking cytolethal distending toxin despite persistent colonization with both strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Cytolethal distending toxin is essential for Helicobacter hepaticus colonization in outbred Swiss Webster mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Bacterial cytolethal distending toxin promotes the development of dysplasia in a model of microbially induced hepatocarcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Is there a risk of cancer development after Campylobacter infection?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X

Immunoproliferative small intestinal disease associated with Campylobacter jejuni

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2011.08125.X