Animal models of airway diseases (Q37874185)

24 August 2017

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title

Animal models of airway diseases (English)

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24 August 2017

Michael R Blackburn

3

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author name string

Linda F Thompson

series ordinal

1

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24 August 2017

Maryse Picher

series ordinal

2

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24 August 2017

publication date

1 January 2011

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24 August 2017

number of pages

40

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Sub-cellular biochemistry

inferred from page(s)

published in

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24 August 2017

volume

55

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24 August 2017

page(s)

195-234

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Transgenic modeling of interleukin-13 in the lung.

24 August 2017

cites work

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12 December 2020

Gene expression profiling in inflammatory airway disease associated with elevated adenosine

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12 December 2020

Mucins, mucus, and sputum

1 reference

12 December 2020

Extracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and fibrosis

1 reference

12 December 2020

Animal models of acute lung injury

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12 December 2020

Purinergic signalling in the immune system. A brief update

1 reference

12 December 2020

Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction

1 reference

12 December 2020

Elevated expression of adenosine A1 receptor in bronchial biopsy specimens from asthmatic subjects.

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12 December 2020

Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells

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12 December 2020

Adenosine triphosphate is released during injurious mechanical ventilation and contributes to lung edema

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12 December 2020

A potential role for P2X7R in allergic airway inflammation in mice and humans

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12 December 2020

P2Y(1) and P2Y(2) receptors are coupled to the NO/cGMP pathway to vasodilate the rat arterial mesenteric bed

1 reference

12 December 2020

Role of extracellular adenosine in acute lung injury

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12 December 2020

The A3 adenosine receptor: an enigmatic player in cell biology

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12 December 2020

CD39 and control of cellular immune responses

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12 December 2020

Liquid movement across the surface epithelium of large airways

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12 December 2020

Pulmonary-derived phosphoinositide 3-kinase gamma (PI3Kγ) contributes to ventilator-induced lung injury and edema

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12 December 2020

Adenosine and inflammation: CD39 and CD73 are critical mediators in LPS-induced PMN trafficking into the lungs

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12 December 2020

Cystic fibrosis remodels the regulation of purinergic signaling by NTPDase1 (CD39) and NTPDase3

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12 December 2020

Enhanced airway reactivity and inflammation in A2A adenosine receptor-deficient allergic mice

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12 December 2020

PEG-ADA replacement therapy for adenosine deaminase deficiency: an update after 8.5 years

1 reference

12 December 2020

Adenosine receptor ligands: potential as therapeutic agents in asthma and COPD.

1 reference

12 December 2020

Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway

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12 December 2020

Purinergic receptors in airway epithelia

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12 December 2020

Adenosine–deaminase–deficient mice die perinatally and exhibit liver–cell degeneration, atelectasis and small intestinal cell death

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12 December 2020

Myosin light chain kinase and Rho-kinase participate in P2Y receptor-mediated acceleration of permeability through the endothelial cell layer

1 reference

12 December 2020

A3 and P2Y2 receptors control the recruitment of neutrophils to the lungs in a mouse model of sepsis

1 reference

12 December 2020

Therapeutic anti-inflammatory effects of myeloid cell adenosine receptor A2a stimulation in lipopolysaccharide-induced lung injury

1 reference

12 December 2020

Effect of adenosine A2A receptor activation in murine models of respiratory disorders

1 reference

12 December 2020

Ca2 -dependent ATP release from A549 cells involves synergistic autocrine stimulation by coreleased uridine nucleotides

1 reference

12 December 2020

Clinical expression of leflunomide-induced pneumonitis

1 reference

12 December 2020

Adenosine inhibits IL-12 and TNF-[alpha] production via adenosine A2a receptor-dependent and independent mechanisms

1 reference

12 December 2020

P2Y receptor-mediated Ca(2 ) signaling increases human vascular endothelial cell permeability

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12 December 2020

Attenuation of chronic pulmonary inflammation in A2B adenosine receptor knockout mice

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12 December 2020

IL-13 as a therapeutic target for respiratory disease

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12 December 2020

Adenosine A3 receptor expression and function in eosinophils

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12 December 2020

ATP antagonism of thrombin-induced endothelial barrier permeability

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12 December 2020

Adenosine deaminase-deficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency

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12 December 2020

The role of adenosine A2A receptor signaling in bronchiolitis obliterans

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12 December 2020

Adenosine inhibits neutrophil vascular endothelial growth factor release and transendothelial migration via A2B receptor activation

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12 December 2020

Cytokines or their antagonists for the treatment of asthma

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12 December 2020

Extracellular adenosine triphosphate and chronic obstructive pulmonary disease.

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12 December 2020

Nucleotide-regulated calcium signaling in lung fibroblasts and epithelial cells from normal and P2Y(2) receptor (-/-) mice

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12 December 2020

Protective effect of purinergic agonist ATPgammaS against acute lung injury

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12 December 2020

Long-term exposure to LPS enhances the rate of stimulated exocytosis and surfactant secretion in alveolar type II cells and upregulates P2Y2 receptor expression

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12 December 2020

Effect of loss of P2Y(2) receptor gene expression on nucleotide regulation of murine epithelial Cl(-) transport

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12 December 2020

Ecto-5'-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia

1 reference

12 December 2020

Enhanced CXCL1 production and angiogenesis in adenosine-mediated lung disease

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12 December 2020

Adenosine protected against pulmonary edema through transporter- and receptor A2-mediated endothelial barrier enhancement

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12 December 2020

Adenosine signaling via the adenosine 2B receptor is involved in bronchiolitis obliterans development

1 reference

12 December 2020

Mass spectrometric analysis of biomarkers and dilution markers in exhaled breath condensate reveals elevated purines in asthma and cystic fibrosis

1 reference

12 December 2020

A3 adenosine receptor signaling contributes to airway inflammation and mucus production in adenosine deaminase-deficient mice

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12 December 2020

Pathogenesis of COPD. Part I. The role of protease-antiprotease imbalance in emphysema

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12 December 2020

Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism

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12 December 2020

Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis

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12 December 2020

Adenosine A3 receptor stimulation inhibits migration of human eosinophils

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12 December 2020

Involvement of A1 adenosine receptors and neural pathways in adenosine-induced bronchoconstriction in mice

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12 December 2020

Increased susceptibility of purinergic receptor-deficient mice to lung infection with Pseudomonas aeruginosa

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12 December 2020

Adenosine regulation of alveolar fluid clearance

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12 December 2020

A2B adenosine receptor dampens hypoxia-induced vascular leak

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12 December 2020

Accelerated variant of idiopathic pulmonary fibrosis: clinical behavior and gene expression pattern

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12 December 2020

Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors

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12 December 2020

Regulated airway goblet cell mucin secretion.

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12 December 2020

P2Y2 receptor regulates VCAM-1 membrane and soluble forms and eosinophil accumulation during lung inflammation

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12 December 2020

Ecto-nucleotidases of the CD39/NTPDase family modulate platelet activation and thrombus formation: Potential as therapeutic targets

1 reference

12 December 2020

Leflunomide prevents alveolar fluid clearance inhibition by respiratory syncytial virus

1 reference

12 December 2020

Mucus hypersecretion in asthma: causes and effects

1 reference

12 December 2020

Crucial role for ecto-5'-nucleotidase (CD73) in vascular leakage during hypoxia

1 reference

12 December 2020

DNA antisense therapy for asthma in an animal model

1 reference

12 December 2020

Adenosine induces fibronectin expression in lung epithelial cells: implications for airway remodeling

1 reference

12 December 2020

5'-Carbamoyl derivatives of 2'-C-methyl-purine nucleosides as selective A1 adenosine receptor agonists: affinity, efficacy, and selectivity for A1 receptor from different species

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12 December 2020

Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice

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12 December 2020

Targeting allograft injury and inflammation in the management of post-lung transplant bronchiolitis obliterans syndrome

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12 December 2020

Effects of adenosine on extravascular lung water content in endotoxemic pigs

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12 December 2020

Attenuation by intravenous 2-chloroadenosine of acute lung injury induced by live escherichia coli or latex particles added to endotoxin in the neutropenic state

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12 December 2020

IL-17A-producing neutrophil-regulatory Tn lymphocytes

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12 December 2020

Biochemical evidence for an ecto alkaline phosphodiesterase I in human airways

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12 December 2020

Ecto-nucleoside triphosphate diphosphohydrolase 1 (E-NTPDase1/CD39) regulates neutrophil chemotaxis by hydrolyzing released ATP to adenosine

1 reference

12 December 2020

Adenosine receptor A3 is a critical mediator in LPS-induced pulmonary inflammation

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12 December 2020

Loss of ATP diphosphohydrolase activity with endothelial cell activation

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12 December 2020

Purinergic receptor inhibition prevents the development of smoke-induced lung injury and emphysema.

1 reference

12 December 2020

Adenosine deaminase 1 and concentrative nucleoside transporters 2 and 3 regulate adenosine on the apical surface of human airway epithelia: implications for inflammatory lung diseases

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12 December 2020

Identification of ectonucleotidases CD39 and CD73 in innate protection during acute lung injury

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12 December 2020

Respiratory syncytial virus inhibits lung epithelial Na channels by up-regulating inducible nitric-oxide synthase.

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12 December 2020

Ecto-5'-nucleotidase (CD73)-mediated adenosine production is tissue protective in a model of bleomycin-induced lung injury

1 reference

12 December 2020

A protective role for the A1 adenosine receptor in adenosine-dependent pulmonary injury

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12 December 2020

Adenosine up-regulation of the mucin gene, MUC2, in asthma

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12 December 2020

A3 adenosine receptor signaling influences pulmonary inflammation and fibrosis

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12 December 2020

nPKCepsilon, a P2Y2-R downstream effector in regulated mucin secretion from airway goblet cells

1 reference

12 December 2020

Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation.

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12 December 2020

Synergy between A2B adenosine receptors and hypoxia in activating human lung fibroblasts

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12 December 2020

ATP reduces macromolecule permeability of endothelial monolayers despite increasing [Ca2 ]i

1 reference

12 December 2020

P2X7 receptor signaling in the pathogenesis of smoke-induced lung inflammation and emphysema

1 reference

12 December 2020

Abnormal alveolar development associated with elevated adenine nucleosides

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12 December 2020

Central role of Sp1-regulated CD39 in hypoxia/ischemia protection

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12 December 2020

Protection from pulmonary ischemia-reperfusion injury by adenosine A2A receptor activation

1 reference

12 December 2020

A2A receptors in inflammation and injury: lessons learned from transgenic animals

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12 December 2020

A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice

1 reference

12 December 2020

Adenosine-dependent pulmonary fibrosis in adenosine deaminase-deficient mice

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12 December 2020

Adenosine signaling and the regulation of chronic lung disease

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12 December 2020

Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

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12 December 2020

Mechanisms of eosinophil recruitment

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12 December 2020

A1 adenosine receptor antagonists block ischemia-reperfusion injury of the lung

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12 December 2020

Adenosine promotes IL-6 release in airway epithelia.

1 reference

12 December 2020

Extracellular purines are biomarkers of neutrophilic airway inflammation

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12 December 2020

A1-adenosine receptor antagonists block endotoxin-induced lung injury

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12 December 2020

Angiogenesis and lymphangiogenesis in bronchial asthma.

1 reference

12 December 2020

Adenosine A2A receptor activation on CD4 T lymphocytes and neutrophils attenuates lung ischemia-reperfusion injury

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12 December 2020

Adenosine Receptor A1 Regulates Polymorphonuclear Cell Trafficking and Microvascular Permeability in Lipopolysaccharide-Induced Lung Injury

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12 December 2020

A3 adenosine receptor signaling contributes to airway mucin secretion after allergen challenge

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12 December 2020

Adenosine A2b receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma

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12 December 2020

ATP in the pathogenesis of lung emphysema

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12 December 2020

Metabolism of P2 receptor agonists in human airways: implications for mucociliary clearance and cystic fibrosis

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12 December 2020

Signaling pathways involved in adenosine triphosphate-induced endothelial cell barrier enhancement

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12 December 2020

Nucleotide-mediated inhibition of alveolar fluid clearance in BALB/c mice after respiratory syncytial virus infection

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12 December 2020

A2B adenosine receptors induce IL-19 from bronchial epithelial cells, resulting in TNF-alpha increase

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12 December 2020

A3 adenosine receptors and mitogen-activated protein kinases in lung injury following in vivo reperfusion

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12 December 2020

VASP is involved in cAMP-mediated Rac 1 activation in microvascular endothelial cells

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12 December 2020

Genetic inactivation of the adenosine A2A receptor attenuates pathologic but not developmental angiogenesis in the mouse retina

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12 December 2020

Effect of A2B adenosine receptor gene ablation on proinflammatory adenosine signaling in mast cells

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12 December 2020

Signaling through the A2B adenosine receptor dampens endotoxin-induced acute lung injury

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12 December 2020

Endothelial damage caused by ischemia and reperfusion and different ventilatory strategies in the lung

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12 December 2020

The purinergic receptor P2Y2 receptor mediates chemotaxis of dendritic cells and eosinophils in allergic lung inflammation

1 reference

12 December 2020

Partially adenosine deaminase-deficient mice develop pulmonary fibrosis in association with adenosine elevations

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12 December 2020

Adherent leukocytes prevent adenosine formation and impair endothelial barrier function by Ecto-5'-nucleotidase/CD73-dependent mechanism

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12 December 2020

Transepithelial migration of neutrophils: mechanisms and implications for acute lung injury

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12 December 2020

Allergen-induced airway hyperresponsiveness is absent in ecto-5'-nucleotidase (CD73)-deficient mice

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12 December 2020

Adenosine A1 receptor antagonist versus montelukast on airway reactivity and inflammation

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12 December 2020

Physiological roles for ecto-5'-nucleotidase (CD73).

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12 December 2020

Production of Interleukin 13 by Alveolar Macrophages from Normal and Fibrotic Lung

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12 December 2020

A2A adenosine receptor induction inhibits IFN-gamma production in murine CD4 T cells

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12 December 2020

Regulators of endothelial and epithelial barrier integrity and function in acute lung injury

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12 December 2020

Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury

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12 December 2020

Effect of a specific and selective A(2B) adenosine receptor antagonist on adenosine agonist AMP and allergen-induced airway responsiveness and cellular influx in a mouse model of asthma

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12 December 2020

In vivo levels and in vitro production of interferon-gamma in fibrosing interstitial lung diseases

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12 December 2020

Ligand-activation of the adenosine A2a receptors inhibits IL-12 production by human monocytes.

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12 December 2020

Adenosine-deaminase deficiency in two patients with severely impaired cellular immunity

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12 December 2020

Adenosine affects expression of membrane molecules, cytokine and chemokine release, and the T-cell stimulatory capacity of human dendritic cells

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12 December 2020

Modulation of epithelial sodium channel activity by lipopolysaccharide in alveolar type II cells: involvement of purinergic signaling.

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12 December 2020

A(2B) adenosine receptors increase cytokine release by bronchial smooth muscle cells.

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12 December 2020

Influenza A virus inhibits alveolar fluid clearance in BALB/c mice

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12 December 2020

Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

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12 December 2020

Types of purinoceptors and phospholipase A2 involved in the activation of the platelet-activating factor-dependent transacetylase activity and arachidonate release by ATP in endothelial cells

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12 December 2020

Purinergic signaling: a fundamental mechanism in neutrophil activation

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12 December 2020

Adenosine-activated mast cells induce IgE synthesis by B lymphocytes: an A2B-mediated process involving Th2 cytokines IL-4 and IL-13 with implications for asthma

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12 December 2020

Adenosine-dependent airway inflammation and hyperresponsiveness in partially adenosine deaminase-deficient mice

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12 December 2020

Inhibition of epithelial sodium channels by respiratory syncytial virus in vitro and in vivo

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12 December 2020

10.1007/978-94-007-1217-1_8

Identifiers

DOI

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24 August 2017

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