Non-viral episomal modification of cells using S/MAR elements (Q37872790)

24 August 2017

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title

Non-viral episomal modification of cells using S/MAR elements (English)

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24 August 2017

Orestis Argyros

1

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24 August 2017

Suet-Ping Wong

series ordinal

2

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24 August 2017

Richard P Harbottle

series ordinal

3

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24 August 2017

language of work or name

English

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publication date

9 May 2011

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Expert Opinion on Biological Therapy

24 August 2017

published in

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24 August 2017

volume

11

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24 August 2017

issue

9

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24 August 2017

page(s)

1177-1191

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Child in gene therapy programme develops leukaemia

24 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Episomal vectors for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Nuclear scaffold/matrix attached region modules linked to a transcription unit are sufficient for replication and maintenance of a mammalian episome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

A vector based on the SV40 origin of replication and chromosomal S/MARs replicates episomally in CHO cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Establishment and mitotic stability of an extra-chromosomal mammalian replicon

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

From DNA structure to gene expression: mediators of nuclear compartmentalization and dynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Role of the intronic elements in the endogenous immunoglobulin heavy chain locus. Either the matrix attachment regions or the core enhancer is sufficient to maintain expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

The effect of matrix attached regions (MAR) and specialized chromatin structure (SCS) on the expression of gene constructs in cultured cells and in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Biological significance of unwinding capability of nuclear matrix-associating DNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Correlations between scaffold/matrix attachment region (S/MAR) binding activity and DNA duplex destabilization energy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

A non-curved chicken lysozyme 5' matrix attachment site is 3' followed by a strongly curved DNA sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

The functional role of S/MARs in episomal vectors as defined by the stress-induced destabilization profile of the vector sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

An episomally replicating vector binds to the nuclear matrix protein SAF-A in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Performance of genomic bordering elements at predefined genomic loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Scaffold/matrix attachment region elements interact with a p300-scaffold attachment factor A complex and are bound by acetylated nucleosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

SAF-B protein couples transcription and pre-mRNA splicing to SAR/MAR elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

The third dimension of gene regulation: organization of dynamic chromatin loopscape by SATB1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

A tissue-specific MAR/SAR DNA-binding protein with unusual binding site recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Exploiting a minimal system to study the epigenetic control of DNA replication: the interplay between transcription and replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

The nonviral episomal replicating vector pEPI-1 allows long-term inhibition of bcr-abl expression by shRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

An episomal mammalian replicon: sequence-independent binding of the origin recognition complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Gene transfer into human hematopoietic progenitor cells with an episomal vector carrying an S/MAR element

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Stable S/MAR-based episomal vectors are regulated at the chromatin level

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Inclusion of a matrix-attached region in a 7SK pol III vector increases the efficiency of shRNA-mediated gene silencing in embryonic carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Long-term suppression of hepatitis B virus replication by short hairpin RNA expression using the scaffold/matrix attachment region-based replicating vector system pEPI-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

An S/MAR-based infectious episomal genomic DNA expression vector provides long-term regulated functional complementation of LDLR deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Genetically modified pigs produced with a nonviral episomal vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Cytoplasmic injection of circular plasmids allows targeted expression in mammalian embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Long-term transgene expression in the central nervous system using DNA nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Persistent episomal transgene expression in liver following delivery of a scaffold/matrix attachment region containing non-viral vector.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Gene therapy progress and prospects: episomally maintained self-replicating systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Non-viral S/MAR vectors replicate episomally in vivo when provided with a selective advantage

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Overexpression of Bcl-2 protects human hepatoma cells from Fas-antibody-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

pEPito: a significantly improved non-viral episomal expression vector for mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Minicircle: an improved DNA molecule for in vitro and in vivo gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Nuclear-targeted minicircle to enhance gene transfer with non-viral vectors in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

An araC-controlled bacterial cre expression system to produce DNA minicircle vectors for nuclear and mitochondrial gene therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Direct comparison of hepatocyte-specific expression cassettes following adenoviral and nonviral hydrodynamic gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Molecular analysis of chromosomal rearrangements in mammalian cells after phiC31-mediated integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Minicircle performance depending on S/MAR-nuclear matrix interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Development of S/MAR minicircles for enhanced and persistent transgene expression in the mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Controlled removal of a nonviral episomal vector from transfected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Minireview: transcriptional regulation in pancreatic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Transgenes encompassing dual-promoter CpG islands from the human TBP and HNRPA2B1 loci are resistant to heterochromatin-mediated silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Optimization of cis-acting elements for gene expression from nonviral vectors in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Intrathecal injection of naked plasmid DNA provides long-term expression of secreted proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Efficient non-viral ocular gene transfer with compacted DNA nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Nanoparticles for retinal gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Distal upstream tyrosinase S/MAR-containing sequence has regulatory properties specific to subsets of melanocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Optimising ultrasound-mediated gene transfer (sonoporation) in vitro and prolonged expression of a transgene in vivo: potential applications for gene therapy of cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Herpes simplex virus thymidine kinase-mediated suicide gene therapy using nano/microbubbles and ultrasound

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Systemic gene transfer of polyethylenimine (PEI)–plasmid DNA complexes to neonatal mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

A new adenoviral helper-dependent vector results in long-term therapeutic levels of human coagulation factor IX at low doses in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Adenovirus transduction is required for the correction of diabetes using Pdx-1 or Neurogenin-3 in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Transduction of brain by herpes simplex virus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

In vivo gene transfer to the rat retina using herpes simplex virus type 1 (HSV-1)-based amplicon vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Herpes simplex virus type 1 amplicon vector-mediated gene transfer to muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Gene transfer into hepatocytes mediated by herpes simplex virus-Epstein-Barr virus hybrid amplicons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Lifelong elimination of hyperbilirubinemia in the Gunn rat with a single injection of helper-dependent adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Effective gene therapy with nonintegrating lentiviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Infectious delivery of a 135-kb LDLR genomic locus leads to regulated complementation of low-density lipoprotein receptor deficiency in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Artificial and engineered chromosomes: non-integrating vectors for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

A highly stable and nonintegrated human artificial chromosome (HAC) containing the 2.4 Mb entire human dystrophin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

Destabilized green fluorescent protein detects rapid removal of transcription blocks after genotoxic exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2011.582035

10.1517/14712598.2011.582035

21 January 2018

Identifiers

DOI

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24 August 2017

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