Crosstalk of TGF-β and Estrogen Receptor Signaling in Breast Cancer (Q37851398)

24 August 2017

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title

Crosstalk of TGF-β and estrogen receptor signaling in breast cancer (English)

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24 August 2017

Crosstalk of TGF-β and Estrogen Receptor Signaling in Breast Cancer (English)

1 reference

DOI

https://api.crossref.org/works/10.1007/S10911-011-9203-7

26 November 2024

1 reference

1 reference

Marikki Laiho

2

1 reference

24 August 2017

Arja M. Band

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21390570

26 November 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21390570

26 November 2024

publication date

11 March 2011

1 reference

full work available at URL

24 August 2017

http://link.springer.com/content/pdf/10.1007/s10911-011-9203-7.pdf

1 reference

https://api.crossref.org/works/10.1007/S10911-011-9203-7

http://link.springer.com/article/10.1007/s10911-011-9203-7/fulltext.html

26 November 2024

1 reference

https://api.crossref.org/works/10.1007/S10911-011-9203-7

http://link.springer.com/content/pdf/10.1007/s10911-011-9203-7

26 November 2024

1 reference

DOI

https://api.crossref.org/works/10.1007/S10911-011-9203-7

Journal of Mammary Gland Biology and Neoplasia

26 November 2024

published in

1 reference

24 August 2017

volume

16

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24 August 2017

issue

2

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24 August 2017

page(s)

109-115

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Mammary gland development and tumorigenesis in estrogen receptor knockout mice

24 August 2017

cites work

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GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptor

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Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation

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SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling

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TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation

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The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction

21 January 2018

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Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation

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Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein

21 January 2018

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The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling

21 January 2018

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Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor

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c-Ski inhibits the TGF-beta signaling pathway through stabilization of inactive Smad complexes on Smad-binding elements

21 January 2018

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Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling

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Ski co-repressor complexes maintain the basal repressed state of the TGF-beta target gene, SMAD7, via HDAC3 and PRMT5

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The phosphatidylinositol 3-kinase/Akt pathway regulates transforming growth factor-{beta} signaling by destabilizing ski and inducing Smad7.

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Signaling by estrogens

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Ski and SnoN, potent negative regulators of TGF-beta signaling

21 January 2018

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SnoN in mammalian development, function and diseases

21 January 2018

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Inability of transforming growth factor-beta to cause SnoN degradation leads to resistance to transforming growth factor-beta-induced growth arrest in esophageal cancer cells

21 January 2018

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12 December 2020

Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN

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The estrogen receptor beta-isoform (ERbeta) of the human estrogen receptor modulates ERalpha transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens

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Identifiers

DOI

1 reference

24 August 2017

1 reference