The role of urokinase-type plasminogen activator in aggressive tumor cell behavior (Q37835073)

24 August 2017

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title

The role of urokinase-type plasminogen activator in aggressive tumor cell behavior (English)

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24 August 2017

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J E Testa

1

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24 August 2017

J P Quigley

series ordinal

2

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24 August 2017

publication date

1 December 1990

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Cancer and Metastasis Reviews

24 August 2017

published in

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24 August 2017

volume

9

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24 August 2017

issue

4

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24 August 2017

page(s)

353-367

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Expression of human recombinant plasminogen activators enhances invasion and experimental metastasis of H-ras-transformed NIH 3T3 cells

24 August 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007/BF00049524

Binding of protease nexin-1 to the fibroblast surface alters its target proteinase specificity

21 January 2018

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12 December 2020

Antibodies to plasminogen activator inhibit human tumor metastasis

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12 December 2020

Growth factors in the regulation of pericellular proteolysis: a review

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12 December 2020

Purification and characterization of a plasminogen activator inhibitor 1 binding protein from human plasma. Identification as a multimeric form of S protein (vitronectin)

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12 December 2020

Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1.

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12 December 2020

Lack of correlation between fibrinolysis and the transformed state of cultured mammalian cells.

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12 December 2020

Role of extracellular matrix in the action of basic fibroblast growth factor: matrix as a source of growth factor for long-term stimulation of plasminogen activator production and DNA synthesis

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12 December 2020

Plasminogen activator inhibitors--a review

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12 December 2020

Urokinase-type plasminogen activator biosynthesis is induced by the EJ-Ha-ras oncogene in CL26 mouse colon carcinoma cells

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12 December 2020

Activation of pro-urokinase and plasminogen on human sarcoma cells: a proteolytic system with surface-bound reactants

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12 December 2020

Interaction of plasminogen activator inhibitor (PAI-1) with vitronectin

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12 December 2020

Differential growth factor expression in transformed mouse NIH-3T3 cells

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12 December 2020

Functional inhibition of endogenously produced urokinase decreases cell proliferation in a human melanoma cell line

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12 December 2020

Human plasma fibronectin as a substrate for human urokinase

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12 December 2020

Mechanism of the Proteolytic Activity of Malignant Tissue Cells

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12 December 2020

Examination of the role of the urokinase receptor in human colon cancer mediated laminin degradation

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12 December 2020

The molecular basis of blood coagulation

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12 December 2020

Effect of plasminogen activator (urokinase), plasmin, and thrombin on glycoprotein and collagenous components of basement membrane

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12 December 2020

An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. II. Mammalian fibroblast cultures transformed by DNA and RNA tumor viruses

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12 December 2020

The action of oncogenes in the cytoplasm and nucleus.

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12 December 2020

Gangliosides interact directly with plasminogen and urokinase and may mediate binding of these fibrinolytic components to cells

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12 December 2020

A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase

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12 December 2020

Plasminogen activators in human malignant melanoma

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12 December 2020

Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc

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12 December 2020

Cell-associated plasminogen activation: regulation and physiological functions

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12 December 2020

Activation of growth factor secretion in tumorigenic states of breast cancer induced by 17 beta-estradiol or v-Ha-ras oncogene

1 reference

12 December 2020

Plasminogen activator gene expression is induced by the src oncogene product and tumor promoters

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12 December 2020

Type 1 plasminogen activator inhibitor

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12 December 2020

A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1 reference

12 December 2020

Test for Malignant Transformation of Rat Liver Cells in Culture: Cytology, Growth in Soft Agar, and Production of Plasminogen Activator

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12 December 2020

Mouse L cells expressing human prourokinase-type plasminogen activator: effects on extracellular matrix degradation and invasion

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12 December 2020

Plasminogen activator dependent pathways in the dissemination of human tumor cells in the chick embryo

1 reference

12 December 2020

Tumor invasion through the human amniotic membrane: requirement for a proteinase cascade

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12 December 2020

Effect of dimethyl sulfoxide on human carcinoma cells, inhibition of plasminogen activator synthesis, change in cell morphology, and alteration of response to cholera toxin

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12 December 2020

Plasminogen activator inhibitors: hormonally regulated serpins

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12 December 2020

The interaction of plasminogen activator with a reconstituted basement membrane matrix and extracellular macromolecules produced by cultured epithelial cells

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12 December 2020

Functional characteristics of receptor-bound urokinase on human monocytes: catalytic efficiency and susceptibility to inactivation by plasminogen activator inhibitors

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12 December 2020

Reexamination of the role of plasminogen activator production for growth in semisolid agar of neoplastic hamster cells.

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12 December 2020

Plasminogen activator-specific inhibitors produced by human monocytes/macrophages

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12 December 2020

In vivo invasion of modified chorioallantoic membrane by tumor cells: the role of cell surface-bound urokinase

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12 December 2020

In vitro degradation of radiolabelled, intact basement membrane mediated by cellular plasminogen activator

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12 December 2020

Evolution of the proteases of blood coagulation and fibrinolysis by assembly from modules

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12 December 2020

Receptor for plasmin on human carcinoma cells

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12 December 2020

One-chain urokinase-type plasminogen activator from human sarcoma cells is a proenzyme with little or no intrinsic activity

1 reference

12 December 2020

The receptor-binding sequence of urokinase. A biological function for the growth-factor module of proteases

1 reference

12 December 2020

Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture

1 reference

12 December 2020

Production of plasminogen activator by cells transformed by herpesviruses

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12 December 2020

Proliferation of a human epidermal tumor cell line stimulated by urokinase

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12 December 2020

Facultative polypeptide translocation allows a single mRNA to encode the secreted and cytosolic forms of plasminogen activators inhibitor 2

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12 December 2020

Secretion of type IV collagenolytic protease and metastatic phenotype: induction by transfection with c-Ha-ras but not c-Ha-ras plus Ad2-E1a

1 reference

12 December 2020

Down-regulation of plasmin receptors on human sarcoma cells by glucocorticoids

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12 December 2020

Inhibition of proteolytic enzymes in the in vitro amnion model for basement membrane invasion.

1 reference

12 December 2020

Modulation of metastatic potential by cell surface urokinase of murine melanoma cells

1 reference

12 December 2020

Destruction of extracellular matrices containing glycoproteins, elastin, and collagen by metastatic human tumor cells

1 reference

12 December 2020

Transformation by oncogenes encoding protein kinases induces the metastatic phenotype

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12 December 2020

Rous-sarcoma-virus-transformed fibroblasts having low levels of plasminogen activator

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12 December 2020

Role of oncogenes in metastases

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12 December 2020

Limited cleavage of cellular fibronectin by plasminogen activator purified from transformed cells

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12 December 2020

Prourokinase activation on the surface of human rhabdomyosarcoma cells: localization and inactivation of newly formed urokinase-type plasminogen activator by recombinant class 2 plasminogen activator inhibitor

1 reference

12 December 2020

Growth stimulation of human epidermal cells by urokinase is restricted to the intact active enzyme

1 reference

12 December 2020

Effects of inhibitors of plasminogen activator, serine proteinases, and collagenase IV on the invasion of basement membranes by metastatic cells.

1 reference

12 December 2020

The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes

1 reference

12 December 2020

The human urokinase-plasminogen activator gene and its promoter.

1 reference

12 December 2020

Role of collagenases in tumor cell invasion

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12 December 2020

p53 increases experimental metastatic capacity of murine carcinoma cells

1 reference

12 December 2020

Determination of the effects of epidermal growth factor on urokinase secretion and urokinase receptor display in a well-differentiated human colon carcinoma cell line

1 reference

12 December 2020

IFN-gamma, tumor necrosis factor-alpha, and urokinase regulate the expression of urokinase receptors on human monocytes

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12 December 2020

ON THE PERMANENT LIFE OF TISSUES OUTSIDE OF THE ORGANISM

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12 December 2020

Inhibition of receptor-bound urokinase by plasminogen-activator inhibitors

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12 December 2020

Immunocytochemical localization of urokinase-type plasminogen activator in Lewis lung carcinoma

1 reference

12 December 2020

The role of proteinase in cellular invasiveness

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12 December 2020

Transforming growth factor alpha (TGF alpha) induction of C-FOS and C-MYC expression in C3H 10T1/2 cells

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12 December 2020

In vitro traits of adenovirus-transformed cell lines and their relevance to tumorigenicity in nude mice

1 reference

12 December 2020

Binding of type 1 plasminogen activator inhibitor to the extracellular matrix of cultured bovine endothelial cells.

1 reference

12 December 2020

Characterization of the cellular binding site for the urokinase-type plasminogen activator

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12 December 2020

fos oncogene transfer to a transformed rat fibroblast cell line enhances spontaneous lung metastasis in rat.

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12 December 2020

Role for cathepsin B and cystatins in tumor growth and progression

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12 December 2020

Distinct localizations of urokinase-type plasminogen activator and its type 1 inhibitor under cultured human fibroblasts and sarcoma cells

1 reference

12 December 2020

Accessibility of receptor-bound urokinase to type-1 plasminogen activator inhibitor

1 reference

12 December 2020

Selective inhibition of proteolytic enzymes in an in vivo mouse model for experimental metastasis

1 reference

12 December 2020

The extracellular matrix of normal chick embryo fibroblasts: its effect on transformed chick fibroblasts and its proteolytic degradation by the transformants

1 reference

12 December 2020

An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. I. Chick embryo fibroblast cultures transformed by avian RNA tumor viruses

1 reference

12 December 2020

Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes

1 reference

12 December 2020

The c-myc-regulated gene mrl encodes plasminogen activator inhibitor 1

1 reference

12 December 2020

Regulation of the synthesis and activity of urokinase plasminogen activator in A549 human lung carcinoma cells by transforming growth factor-beta

1 reference

12 December 2020

Examination of the effects of epidermal growth factor on the production of urokinase and the expression of the plasminogen activator receptor in a human colon cancer cell line

1 reference

12 December 2020

Effects of cellular transformation on expression of plasminogen activator inhibitors 1 and 2. Evidence for independent regulation.

1 reference

12 December 2020

The human receptor for urokinase plasminogen activator. NH2-terminal amino acid sequence and glycosylation variants

1 reference

12 December 2020

Plasminogen activators, tissue degradation, and cancer

1 reference

12 December 2020

Extracellular matrix of cultured bovine aortic endothelial cells contains functionally active type 1 plasminogen activator inhibitor

1 reference

12 December 2020

Plasminogen activator in cultured Lewis lung carcinoma cells measured by chromogenic substrate assay

1 reference

12 December 2020

Purification of a protein from bovine plasma that binds to type 1 plasminogen activator inhibitor and prevents its interaction with extracellular matrix. Evidence that the protein is vitronectin

1 reference

12 December 2020

Synergistic effect of tumor virus transformation and tumor promoter treatment on the production of plasminogen activator by chick embryo fibroblasts

1 reference

12 December 2020

Antimetastatic effect of amiloride in an animal tumour model

1 reference

12 December 2020

Transforming growth factor-beta induction of type-1 plasminogen activator inhibitor. Pericellular deposition and sensitivity to exogenous urokinase

1 reference

12 December 2020

An anticatalytic monoclonal antibody to avian plasminogen activator: its effect on behavior of RSV-transformed chick fibroblasts

1 reference

12 December 2020

Plasminogen activator production accompanies loss of anchorage regulation in transformation of primary rat embryo cells by simian virus 40.

1 reference

12 December 2020

Regulation of urokinase receptors in monocytelike U937 cells by phorbol ester phorbol myristate acetate

1 reference

12 December 2020

Induction of urokinase activity and malignant phenotype in bladder carcinoma cells after transfection of the activated Ha-ras oncogene

1 reference

12 December 2020

Analysis of metastatic competence of mouse bladder carcinoma cells after transfection with activated Ha-ras or N-ras oncogenes

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00049524

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24 August 2017

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