Feedback regulation of EGFR signalling: decision making by early and delayed loops. (Q37831109)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21252999 AND SRC:MED&resulttype=core&format=json

20 January 2020

review article

1 reference

title

Feedback regulation of EGFR signalling: decision making by early and delayed loops (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21252999 AND SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21252999 AND SRC:MED&resulttype=core&format=json

20 January 2020

author name string

Yosef Yarden

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21252999 AND SRC:MED&resulttype=core&format=json

20 January 2020

publication date

1 February 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21252999 AND SRC:MED&resulttype=core&format=json

Nature Reviews Molecular Cell Biology

20 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21252999 AND SRC:MED&resulttype=core&format=json

20 January 2020

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21252999 AND SRC:MED&resulttype=core&format=json

20 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21252999 AND SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

104-117

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21252999 AND SRC:MED&resulttype=core&format=json

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

20 January 2020

cites work

1 reference

Tyrosine phosphorylation: thirty years and counting

31 March 2020

1 reference

Signaling Through Scaffold, Anchoring, and Adaptor Proteins

31 March 2020

1 reference

EGF-ERBB signalling: towards the systems level

31 March 2020

1 reference

Cell-signalling dynamics in time and space

31 March 2020

1 reference

Feedback control of intercellular signalling in development

31 March 2020

1 reference

A positive-feedback-based bistable 'memory module' that governs a cell fate decision

31 March 2020

1 reference

31 March 2020

Biological robustness

1 reference

Signalling ballet in space and time

31 March 2020

1 reference

Cell signaling by receptor tyrosine kinases

31 March 2020

1 reference

Genetic regulatory mechanisms in the synthesis of proteins

31 March 2020

2 references

31 March 2020

12 December 2020

CANALIZATION OF DEVELOPMENT AND THE INHERITANCE OF ACQUIRED CHARACTERS

1 reference

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts

31 March 2020

1 reference

A signaling organelle containing the nerve growth factor-activated receptor tyrosine kinase, TrkA

31 March 2020

1 reference

Control of EGF receptor signaling by clathrin-mediated endocytosis.

31 March 2020

1 reference

Ras/MAPK signaling from endomembranes

31 March 2020

1 reference

Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor

31 March 2020

1 reference

Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation

31 March 2020

1 reference

Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

31 March 2020

1 reference

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

31 March 2020

1 reference

A two-tiered mechanism of EGFR inhibition by RALT/MIG6 via kinase suppression and receptor degradation.

31 March 2020

1 reference

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

31 March 2020

1 reference

Conjugation to Nedd8 instigates ubiquitylation and down-regulation of activated receptor tyrosine kinases

31 March 2020

1 reference

Endocytosis of Receptor Tyrosine Kinases Is Driven by Monoubiquitylation, Not Polyubiquitylation

31 March 2020

1 reference

Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

31 March 2020

1 reference

Receptor downregulation and multivesicular-body sorting

31 March 2020

1 reference

A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins

31 March 2020

1 reference

Differential effects of EGFR ligands on endocytic sorting of the receptor.

31 March 2020

1 reference

Breakdown of endocytosis in the oncogenic activation of receptor tyrosine kinases

31 March 2020

1 reference

Regulation of endocytosis via the oxygen-sensing pathway

31 March 2020

1 reference

Membrane curvature and mechanisms of dynamic cell membrane remodelling

31 March 2020

1 reference

Imaging actin and dynamin recruitment during invagination of single clathrin-coated pits

31 March 2020

1 reference

Cbl promotes clustering of endocytic adaptor proteins.

31 March 2020

1 reference

Endocytosis: the DUB version

31 March 2020

1 reference

Activation of the endosome-associated ubiquitin isopeptidase AMSH by STAM, a component of the multivesicular body-sorting machinery

31 March 2020

1 reference

Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo

31 March 2020

1 reference

Imaging sites of receptor dephosphorylation by PTP1B on the surface of the endoplasmic reticulum

31 March 2020

1 reference

Membrane contacts between endosomes and ER provide sites for PTP1B-epidermal growth factor receptor interaction

31 March 2020

1 reference

PTP1B targets the endosomal sorting machinery: dephosphorylation of regulatory sites on the endosomal sorting complex required for transport component STAM2.

31 March 2020

1 reference

Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP

31 March 2020

1 reference

Receptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor function

31 March 2020

1 reference

The C. elegans homolog of the mammalian tumor suppressor Dep-1/Scc1 inhibits EGFR signaling to regulate binary cell fate decisions

31 March 2020

1 reference

An unbiased screen identifies DEP-1 tumor suppressor as a phosphatase controlling EGFR endocytosis

31 March 2020

1 reference

Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers

31 March 2020

1 reference

Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B

31 March 2020

1 reference

PTPD1 supports receptor stability and mitogenic signaling in bladder cancer cells

31 March 2020

1 reference

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

31 March 2020

1 reference

c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function

31 March 2020

1 reference

p38 MAP kinase mediates stress-induced internalization of EGFR: implications for cancer chemotherapy

31 March 2020

1 reference

Phosphorylation and regulation of Raf by Akt (protein kinase B)

31 March 2020

1 reference

Regulation of Raf-1 activation and signalling by dephosphorylation

31 March 2020

1 reference

Regulation of Raf-1 by direct feedback phosphorylation.

31 March 2020

1 reference

Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma

31 March 2020

1 reference

MicroRNAs: genomics, biogenesis, mechanism, and function

31 March 2020

1 reference

A microRNA mediates EGF receptor signaling and promotes photoreceptor differentiation in the Drosophila eye

31 March 2020

1 reference

SMAD proteins control DROSHA-mediated microRNA maturation

31 March 2020

1 reference

Primary response genes induced by growth factors and tumor promoters

31 March 2020

1 reference

A module of negative feedback regulators defines growth factor signaling

31 March 2020

1 reference

Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc

31 March 2020

1 reference

Control of inducible gene expression by signal-dependent transcriptional elongation

31 March 2020

1 reference

Negative elongation factor NELF controls transcription of immediate early genes in a stimulus-specific manner

31 March 2020

1 reference

A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling

31 March 2020

1 reference

Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes

31 March 2020

1 reference

A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts

31 March 2020

1 reference

Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin

31 March 2020

1 reference

Involvement of microRNA in AU-rich element-mediated mRNA instability

31 March 2020

1 reference

EMT, the cytoskeleton, and cancer cell invasion

31 March 2020

1 reference

N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression

31 March 2020

1 reference

A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration

31 March 2020

1 reference

Autocrine secretion and malignant transformation of cells.

31 March 2020

1 reference

EGF-receptor-mediated mammary epithelial cell migration is driven by sustained ERK signaling from autocrine stimulation

31 March 2020

1 reference

Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop

31 March 2020

1 reference

The response of human epithelial cells to TNF involves an inducible autocrine cascade

31 March 2020

1 reference

An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells

31 March 2020

1 reference

Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab

31 March 2020

1 reference

Network motifs: theory and experimental approaches

31 March 2020

1 reference

Modular Response Analysis of Cellular Regulatory Networks

31 March 2020

1 reference

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

31 March 2020

1 reference

The beta-PDGF receptor induces neuronal differentiation of PC12 cells

31 March 2020

1 reference

Quantitative transcriptional control of ErbB receptor signaling undergoes graded to biphasic response for cell differentiation.

31 March 2020

1 reference

Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate

31 March 2020

1 reference

Molecular interpretation of ERK signal duration by immediate early gene products

31 March 2020

1 reference

Prediction and validation of the distinct dynamics of transient and sustained ERK activation

31 March 2020

1 reference

Cell fate decisions are specified by the dynamic ERK interactome

31 March 2020

1 reference

Receptor downregulation and desensitization enhance the information processing ability of signalling receptors

31 March 2020

1 reference

Increased accuracy of ligand sensing by receptor internalization

31 March 2020

1 reference

Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP

31 March 2020

1 reference

Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein

31 March 2020

1 reference

MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network

31 March 2020

1 reference

Dynamics of the p53-Mdm2 feedback loop in individual cells

31 March 2020

1 reference

Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades

31 March 2020

1 reference

SOS phosphorylation and disassociation of the Grb2-SOS complex by the ERK and JNK signaling pathways

31 March 2020

1 reference

Insulin and epidermal growth factor receptors regulate distinct pools of Grb2-SOS in the control of Ras activation

31 March 2020

1 reference

Positive- and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway

31 March 2020

1 reference

Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor

31 March 2020

1 reference

Dynamics and variability of ERK2 response to EGF in individual living cells

31 March 2020

1 reference

Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription

31 March 2020

1 reference

Network biology: understanding the cell's functional organization

31 March 2020

1 reference

Mathematical and computational analysis of adaptation via feedback inhibition in signal transduction pathways

31 March 2020

1 reference

Defining network topologies that can achieve biochemical adaptation.

31 March 2020

1 reference

Evidence that fold-change, and not absolute level, of beta-catenin dictates Wnt signaling

31 March 2020

1 reference

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

31 March 2020

1 reference

Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.

31 March 2020

1 reference

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

31 March 2020

1 reference

Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling.

31 March 2020

1 reference

Pathogenic poxviruses reveal viral strategies to exploit the ErbB signaling network

31 March 2020

1 reference

Engineering epidermal growth factor for enhanced mitogenic potency

31 March 2020

1 reference

Analysis of the transcriptional program induced by Raf in epithelial cells

31 March 2020

1 reference

Mig-6 controls EGFR trafficking and suppresses gliomagenesis

31 March 2020

1 reference

Flt3-dependent transformation by inactivating c-Cbl mutations in AML

31 March 2020

1 reference

Quantifying the Gurken morphogen gradient in Drosophila oogenesis

31 March 2020

1 reference

Network motifs in integrated cellular networks of transcription-regulation and protein-protein interaction

31 March 2020

1 reference

EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor

31 March 2020

1 reference

Relevance of biologic markers in colorectal carcinoma: a comparative study of a broad panel

31 March 2020

1 reference

12 December 2020

Expression of leucine-rich repeats and immunoglobulin-like domains (LRIG) proteins in human ependymoma relates to tumor location, WHO grade, and patient age.

1 reference

12 December 2020

EGF decreases the abundance of microRNAs that restrain oncogenic transcription factors

1 reference

12 December 2020

Huntingtin-interacting protein 1 is overexpressed in prostate and colon cancer and is critical for cellular survival

1 reference

12 December 2020

Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6

1 reference

12 December 2020

Modular response analysis of cellular regulatory networks.

1 reference

12 December 2020

Effects of the extract of the mouse submaxillary salivary glands on the sympathetic system of mammals

1 reference

12 December 2020

Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity

1 reference

12 December 2020

Postendocytic trafficking of epidermal growth factor-receptor complexes is mediated through saturable and specific endosomal interactions.

1 reference

12 December 2020

Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRM3048

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21252999 AND SRC:MED&resulttype=core&format=json

20 January 2020

1 reference