Cell lineage and cell death: Caenorhabditis elegans and cancer research (Q37820053)

23 August 2017

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title

Cell lineage and cell death: Caenorhabditis elegans and cancer research (English)

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23 August 2017

main subject

Caenorhabditis elegans

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1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21150934

19 November 2024

author name string

Scott Cameron

series ordinal

2

1 reference

23 August 2017

Malia B. Potts

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21150934

19 November 2024

language of work or name

English

0 references

publication date

2 December 2010

1 reference

full work available at URL

23 August 2017

http://www.nature.com/articles/nrc2984.pdf

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http://www.nature.com/articles/nrc2984

19 November 2024

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19 November 2024

published in

Nature Reviews Cancer

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23 August 2017

volume

11

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23 August 2017

issue

1

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23 August 2017

page(s)

50-58

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

23 August 2017

cites work

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The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3

21 January 2018

1 reference

Hoxa9/hoxb3/hoxb4 compound null mice display severe hematopoietic defects

21 January 2018

1 reference

Genetic control of programmed cell death in Drosophila

21 January 2018

1 reference

Genetic control of programmed cell death in the nematode C. elegans.

31 March 2020

1 reference

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

31 March 2020

1 reference

Post-embryonic cell lineages of the nematode, Caenorhabditis elegans

31 March 2020

1 reference

The embryonic cell lineage of the nematode Caenorhabditis elegans

31 March 2020

1 reference

Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells

31 March 2020

1 reference

Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation

31 March 2020

1 reference

The zinc-finger proto-oncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineages

31 March 2020

1 reference

Imaging hematopoietic precursor division in real time

31 March 2020

1 reference

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

31 March 2020

1 reference

The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death

31 March 2020

1 reference

Caenorhabditis elegans gene ced-9 protects cells from programmed cell death

31 March 2020

1 reference

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

31 March 2020

1 reference

The TRA-1A sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-1 cell death activator gene

31 March 2020

1 reference

The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9

31 March 2020

1 reference

Worms, life, and death (Nobel lecture).

31 March 2020

1 reference

Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2

31 March 2020

1 reference

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

31 March 2020

1 reference

Proapoptotic BID is required for myeloid homeostasis and tumor suppression

31 March 2020

1 reference

Bad-deficient mice develop diffuse large B cell lymphoma

31 March 2020

1 reference

Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans

31 March 2020

1 reference

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

31 March 2020

1 reference

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

31 March 2020

1 reference

Living with death: the evolution of the mitochondrial pathway of apoptosis in animals.

31 March 2020

1 reference

Inhibitor of apoptosis proteins in Drosophila: gatekeepers of death

31 March 2020

1 reference

Cell death inhibition: keeping caspases in check

31 March 2020

1 reference

Timing of the onset of a developmental cell death is controlled by transcriptional induction of the C. elegans ced-3 caspase-encoding gene

31 March 2020

1 reference

Pax2/5/8 proteins promote cell survival in C. elegans

31 March 2020

1 reference

Transcriptional upregulation of both egl-1 BH3-only and ced-3 caspase is required for the death of the male-specific CEM neurons

31 March 2020

1 reference

Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2.

31 March 2020

1 reference

The C. elegans cell death specification gene ces-1 encodes a snail family zinc finger protein

31 March 2020

1 reference

The Snail-like CES-1 protein of C. elegans can block the expression of the BH3-only cell-death activator gene egl-1 by antagonizing the function of bHLH proteins

31 March 2020

1 reference

Reversal of apoptosis by the leukaemia-associated E2A-HLF chimaeric transcription factor

31 March 2020

1 reference

Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia

31 March 2020

1 reference

Human Slug is a repressor that localizes to sites of active transcription

31 March 2020

1 reference

SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein

31 March 2020

1 reference

Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma

31 March 2020

1 reference

Control of apoptosis by asymmetric cell division

31 March 2020

1 reference

Spindle regulation in neural precursors of flies and mammals

31 March 2020

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Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer

31 March 2020

1 reference

Control of sex-specific apoptosis in C. elegans by the BarH homeodomain protein CEH-30 and the transcriptional repressor UNC-37/Groucho

31 March 2020

1 reference

The C. elegans protein CEH-30 protects male-specific neurons from apoptosis independently of the Bcl-2 homolog CED-9.

31 March 2020

1 reference

A novel POU homeodomain gene specifically expressed in cells of the developing mammalian nervous system

31 March 2020

1 reference

Oct-3/4 is a dose-dependent oncogenic fate determinant

31 March 2020

1 reference

Targeting Brn-3b in breast cancer therapy

31 March 2020

1 reference

Implication of leucyl-tRNA synthetase 1 (LARS1) over-expression in growth and migration of lung cancer cells detected by siRNA targeted knock-down analysis

31 March 2020

1 reference

The 'Marx' of Groucho on development and disease

31 March 2020

1 reference

Potential roles for the PIM1 kinase in human cancer - a molecular and therapeutic appraisal

31 March 2020

1 reference

Molecular analysis of the C. elegans sex-determining gene tra-1: a gene encoding two zinc finger proteins

31 March 2020

1 reference

A paracrine requirement for hedgehog signalling in cancer

31 March 2020

1 reference

Essential role of stromally induced hedgehog signaling in B-cell malignancies

31 March 2020

1 reference

Activation of the BCL2 promoter in response to Hedgehog/GLI signal transduction is predominantly mediated by GLI2

31 March 2020

1 reference

Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1.

31 March 2020

1 reference

Six and Eya promote apoptosis through direct transcriptional activation of the proapoptotic BH3-only gene egl-1 in Caenorhabditis elegans

31 March 2020

1 reference

The six family of homeobox genes in development and cancer

31 March 2020

1 reference

Control of cell fates in the central body region of C. elegans by the homeobox gene lin-39.

31 March 2020

1 reference

Multiple HOM-C gene interactions specify cell fates in the nematode central nervous system

31 March 2020

1 reference

A gene involved in the development of the posterior body region of C. elegans

31 March 2020

1 reference

Patterning of Caenorhabditis elegans posterior structures by the Abdominal-B homolog, egl-5.

31 March 2020

1 reference

Hox gene evolution in nematodes: novelty conserved

31 March 2020

1 reference

The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein.

31 March 2020

1 reference

Direct regulation of egl-1 and of programmed cell death by the Hox protein MAB-5 and by CEH-20, a C. elegans homolog of Pbx1.

31 March 2020

1 reference

The roles of two C. elegans HOX co-factor orthologs in cell migration and vulva development

31 March 2020

1 reference

Conserved regulation of the Caenorhabditis elegans labial/Hox1 gene ceh-13.

31 March 2020

1 reference

Hox cofactors in vertebrate development

31 March 2020

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Trithorax, Hox, and TALE-class homeodomain proteins ensure cell survival through repression of the BH3-only gene egl-1.

31 March 2020

1 reference

The Drosophila Hox gene deformed sculpts head morphology via direct regulation of the apoptosis activator reaper

31 March 2020

1 reference

Antagonistic roles for Ultrabithorax and Antennapedia in regulating segment-specific apoptosis of differentiated motoneurons in the Drosophila embryonic central nervous system

31 March 2020

1 reference

HOXA9 is required for survival in human MLL-rearranged acute leukemias

31 March 2020

1 reference

Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins.

31 March 2020

1 reference

Deregulation of PAX-5 by translocation of the Emu enhancer of the IgH locus adjacent to two alternative PAX-5 promoters in a diffuse large-cell lymphoma

31 March 2020

1 reference

Structural characterization of the FKHR gene and its rearrangement in alveolar rhabdomyosarcoma

31 March 2020

1 reference

Paired-Box genes are frequently expressed in cancer and often required for cancer cell survival

31 March 2020

1 reference

Transcriptional modulation of the anti-apoptotic protein BCL-XL by the paired box transcription factors PAX3 and PAX3/FKHR

31 March 2020

1 reference

C. elegans orthologs of components of the RB tumor suppressor complex have distinct pro-apoptotic functions

31 March 2020

1 reference

Death and more: DNA damage response pathways in the nematode C. elegans.

31 March 2020

1 reference

HIF-1 antagonizes p53-mediated apoptosis through a secreted neuronal tyrosinase

31 March 2020

1 reference

DPL-1 DP, LIN-35 Rb and EFL-1 E2F act with the MCD-1 zinc-finger protein to promote programmed cell death in Caenorhabditis elegans

31 March 2020

1 reference

MLL targets SET domain methyltransferase activity to Hox gene promoters

31 March 2020

1 reference

The role of MLL in hematopoiesis and leukemia

31 March 2020

1 reference

MLL translocations, histone modifications and leukaemia stem-cell development

31 March 2020

1 reference

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

31 March 2020

1 reference

Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 trial

31 March 2020

1 reference

Acute lymphoblastic leukemia

31 March 2020

1 reference

A comprehensive genetic classification of adult acute lymphoblastic leukemia (ALL): analysis of the GIMEMA 0496 protocol

31 March 2020

1 reference

Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells

31 March 2020

1 reference

Hoxb3 deficiency impairs B lymphopoiesis in mouse bone marrow.

31 March 2020

1 reference

Hoxb4-deficient mice undergo normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells

31 March 2020

1 reference

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

31 March 2020

1 reference

Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential.

31 March 2020

1 reference

Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia.

31 March 2020

1 reference

Hoxa9 influences the phenotype but not the incidence of Mll-AF9 fusion gene leukemia

31 March 2020

1 reference

Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9

31 March 2020

1 reference

HoxA9-mediated immortalization of myeloid progenitors requires functional interactions with TALE cofactors Pbx and Meis

31 March 2020

1 reference

Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia

31 March 2020

1 reference

E2A-HLF usurps control of evolutionarily conserved survival pathways

31 March 2020

1 reference

Tissue repair and stem cell renewal in carcinogenesis

31 March 2020

1 reference

Cancer: Hedgehog's other great trick

31 March 2020

1 reference

The role of HOX genes in malignant myeloid disease

31 March 2020

1 reference

Unraveling the crucial roles of Meis1 in leukemogenesis and normal hematopoiesis

31 March 2020

1 reference

Hox regulation of normal and leukemic hematopoietic stem cells.

31 March 2020

1 reference

The pathophysiology of HOX genes and their role in cancer.

31 March 2020

1 reference

Fusions involving PAX and FOX genes in the molecular pathogenesis of alveolar rhabdomyosarcoma: recent advances

31 March 2020

1 reference

Cdx genes, inflammation and the pathogenesis of Barrett's metaplasia

31 March 2020

1 reference

Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model

31 March 2020

1 reference

The role of Cdx proteins in intestinal development and cancer

31 March 2020

1 reference

Genetic and cellular basis for acetylcholine inhibition of Caenorhabditis elegans egg-laying behavior.

31 March 2020

1 reference

Roles of the Homothorax/Meis/Prep homolog UNC-62 and the Exd/Pbx homologs CEH-20 and CEH-40 in C. elegans embryogenesis.

31 March 2020

1 reference

12 December 2020

Overlapping roles of two Hox genes and the exd ortholog ceh-20 in diversification of the C. elegans postembryonic mesoderm.

1 reference

12 December 2020

Mutations causing transformation of sexual phenotype in the nematode Caenorhabditis elegans

1 reference

12 December 2020

PAG-3, a Zn-finger transcription factor, determines neuroblast fate in C. elegans.

1 reference

12 December 2020

The C. elegans gene pag-3 is homologous to the zinc finger proto-oncogene gfi-1.

1 reference

12 December 2020

Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline.

1 reference

12 December 2020

Mice bearing a targeted interruption of the homeobox gene HOXA9 have defects in myeloid, erythroid, and lymphoid hematopoiesis.

1 reference

12 December 2020

Biological and therapeutic aspects of infant leukemia

1 reference

12 December 2020

The POU domain transcription factor Brn-2: elevated expression in malignant melanoma and regulation of melanocyte-specific gene expression

1 reference

12 December 2020

Control of cell fate in the tail region of C. elegans by the gene egl-5

1 reference

12 December 2020

Fusion of PAX3 to a member of the forkhead family of transcription factors in human alveolar rhabdomyosarcoma.

1 reference

12 December 2020

The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties

1 reference

12 December 2020

Sex determination in the germ line

1 reference

12 December 2020

Anterior organization of the Caenorhabditis elegans embryo by the labial-like Hox gene ceh-13.

1 reference

12 December 2020

The t(1;19)(q23;p13) results in consistent fusion of E2A and PBX1 coding sequences in acute lymphoblastic leukemias

1 reference

12 December 2020

Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes

1 reference

12 December 2020

The role of chromosome translocations in leukemogenesis.

1 reference

12 December 2020

Two C. elegans genes control the programmed deaths of specific cells in the pharynx

1 reference

12 December 2020

MUTATIONS CAUSING TRANSFORMATION OF SEXUAL PHENOTYPE IN THE NEMATODE <i>CAENORHABDITIS ELEGANS</i>

series ordinal

48

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19 November 2024

88

53

5108

DN Shapiro

1993

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19 November 2024

Identifiers

DOI

10.1038/NRC2984

1 reference

release_v4tcnrbpt5bufcktzm7kg4bc6m

23 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/v4tcnrbpt5bufcktzm7kg4bc6m

24 November 2022

mapped directly with Wikidata item

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