Probes for studying cholesterol binding and cell biology (Q37809216)

23 August 2017

title

Probes for studying cholesterol binding and cell biology (English)

1 reference

23 August 2017

1 reference

2

Katja Gehrig-Burger

1 reference

23 August 2017

1

Gerald Gimpl

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21074546

26 August 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21074546

26 August 2024

publication date

11 November 2010

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full work available at URL

23 August 2017

number of pages

16

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based on heuristic

inferred from page(s)

https://api.elsevier.com/content/article/PII:S0039128X10002667?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

https://api.elsevier.com/content/article/PII:S0039128X10002667?httpAccept=text/plain

26 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

26 August 2024

1 reference

23 August 2017

volume

76

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23 August 2017

issue

3

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23 August 2017

page(s)

216-231

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Regulation of receptor function by cholesterol.

23 August 2017

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Lipid rafts and signal transduction

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Cholesterol and the cell membrane

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Cholesterol domains in biological membranes

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Significance of sterol structural specificity. Desmosterol cannot replace cholesterol in lipid rafts

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Cholesterol reporter molecules

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Differential effects of alpha-, beta- and gamma-cyclodextrins on human erythrocytes

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Alteration of the myometrial plasma membrane cholesterol content with beta-cyclodextrin modulates the binding affinity of the oxytocin receptor

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Expression of the Human Oxytocin Receptor in Baculovirus-Infected Insect Cells: High-Affinity Binding Is Induced by a Cholesterol-Cyclodextrin Complex

26 August 2024

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Cellular cholesterol efflux mediated by cyclodextrins

26 August 2024

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Cholesterol as modulator of receptor function.

26 August 2024

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Use of cyclodextrins to manipulate plasma membrane cholesterol content: evidence, misconceptions and control strategies

26 August 2024

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Cholesterol depletion induces large scale domain segregation in living cell membranes

26 August 2024

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Limited cholesterol depletion causes aggregation of plasma membrane lipid rafts inducing T cell activation

26 August 2024

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Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism

26 August 2024

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Reversal of defective lysosomal transport in NPC disease ameliorates liver dysfunction and neurodegeneration in the npc1-/- mouse

26 August 2024

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Cyclodextrin overcomes deficient lysosome-to-endoplasmic reticulum transport of cholesterol in Niemann-Pick type C cells

26 August 2024

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Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells

26 August 2024

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Effects of cholesterol depletion by cyclodextrin on the sphingolipid microdomains of the plasma membrane

26 August 2024

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Dynamics of membrane lipid domains in neuronal cells differentiated in culture

26 August 2024

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Behavior of alpha-, beta-, and gamma-cyclodextrins and their derivatives on an in vitro model of blood-brain barrier.

26 August 2024

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Critical role for cholesterol in Lyn-mediated tyrosine phosphorylation of FcepsilonRI and their association with detergent-resistant membranes

26 August 2024

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Clathrin-independent internalization of the human histamine H1-receptor in CHO-K1 cells

26 August 2024

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T cell signal regulation by the actin cytoskeleton

26 August 2024

40

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Membrane cholesterol modulates galanin-GalR2 interaction

26 August 2024

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Filipin vs enzymatic localization of cholesterol in guinea pig, mink, and mallard duck testicular cells

26 August 2024

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Detection of membrane cholesterol by filipin in isolated rat liver coated vesicles is dependent upon removal of the clathrin coat

26 August 2024

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Failure of filipin to detect cholesterol-rich domains in smooth muscle plasma membrane

26 August 2024

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The cholesterol-dependent cytolysin family of gram-positive bacterial toxins.

26 August 2024

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Cholesterol-binding toxins and anti-cholesterol antibodies as structural probes for cholesterol localization

26 August 2024

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Sterol structural requirements for inhibition of streptolysin O activity

26 August 2024

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Interaction of streptolysin O with sterols

26 August 2024

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How interaction of perfringolysin O with membranes is controlled by sterol structure, lipid structure, and physiological low pH: insights into the origin of perfringolysin O-lipid raft interaction

26 August 2024

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26 August 2024

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26 August 2024

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Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface

26 August 2024

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Crosslinked Plasmalemmal Cholesterol Is Sequestered to Caveolae: Analysis with a New Cytochemical Probe

26 August 2024

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A biotinylated perfringolysin O derivative: A new probe for detection of cell surface cholesterol

26 August 2024

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Selective binding of perfringolysin O derivative to cholesterol-rich membrane microdomains (rafts).

26 August 2024

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Immunoelectron microscopic localization of cholesterol using biotinylated and non-cytolytic perfringolysin O.

26 August 2024

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Biotinylated theta-toxin derivative as a probe to examine intracellular cholesterol-rich domains in normal and Niemann-Pick type C1 cells

26 August 2024

58

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A novel cholesterol stain reveals early neuronal cholesterol accumulation in the Niemann-Pick type C1 mouse brain

26 August 2024

59

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Axon-dominant localization of cell-surface cholesterol in cultured hippocampal neurons and its disappearance in Niemann-Pick type C model cells

26 August 2024

60

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Effect of lipidic factors on membrane cholesterol topology--mode of binding of theta-toxin to cholesterol in liposomes

26 August 2024

61

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The C-terminal domain of perfringolysin O is an essential cholesterol-binding unit targeting to cholesterol-rich microdomains.

26 August 2024

62

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Dissecting the molecular mechanisms of polarized membrane traffic: reconstitution of three transport steps in epithelial cells using streptolysin-O permeabilization

26 August 2024

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Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of pregnenolone and 3'-phosphoadenosine 5'-phosphate. Rationale for specificity differences between prototypical SULT2A1 and the SULT2BG1 isoforms

26 August 2024

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Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain

26 August 2024

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Cholesterol oxidase: sources, physical properties and analytical applications

26 August 2024

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Cholesterol oxidase: biochemistry and structural features

26 August 2024

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Spontaneous transfer between phospholipid bilayers of dehydroergosterol, a fluorescent cholesterol analog

26 August 2024

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Cholesterol oxidase senses subtle changes in lipid bilayer structure

26 August 2024

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Activation of membrane cholesterol by 63 amphipaths

26 August 2024

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Cholesterol oxidase susceptibility of the red cell membrane

26 August 2024

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Effects of sphingomyelin degradation on cell cholesterol oxidizability and steady-state distribution between the cell surface and the cell interior

26 August 2024

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Activation of membrane cholesterol by displacement from phospholipids

26 August 2024

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Chemical activity of cholesterol in membranes

26 August 2024

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How cholesterol homeostasis is regulated by plasma membrane cholesterol in excess of phospholipids

26 August 2024

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ABCG1 redistributes cell cholesterol to domains removable by high density lipoprotein but not by lipid-depleted apolipoproteins

26 August 2024

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Caveolin moves from caveolae to the Golgi apparatus in response to cholesterol oxidation

26 August 2024

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Cholesterol oxidation switches the internalization pathway of endothelin receptor type A from caveolae to clathrin-coated pits in Chinese hamster ovary cells

26 August 2024

81

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Cholesterol oxidase catalyzed oxidation of cholesterol in mixed lipid monolayers: effects of surface pressure and phospholipid composition on catalytic activity

26 August 2024

82

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The Effect of Sterol Structure on Membrane Lipid Domains Reveals How Cholesterol Can Induce Lipid Domain Formation†

26 August 2024

83

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X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha

26 August 2024

84

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The Binding and Release of Oxygen and Hydrogen Peroxide Are Directed by a Hydrophobic Tunnel in Cholesterol Oxidase †

26 August 2024

85

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Structural mechanism for sterol sensing and transport by OSBP-related proteins

26 August 2024

86

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A porcine homolog of the major secretory protein of human epididymis, HE1, specifically binds cholesterol

26 August 2024

87

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The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels.

26 August 2024

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NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes

26 August 2024

89

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Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease

26 August 2024

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NPC2, the protein deficient in Niemann-Pick C2 disease, consists of multiple glycoforms that bind a variety of sterols

26 August 2024

91

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Mechanism of cholesterol transfer from the Niemann-Pick type C2 protein to model membranes supports a role in lysosomal cholesterol transport

26 August 2024

92

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The sterol-sensing domain: multiple families, a unique role?

26 August 2024

93

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Binding between the Niemann-Pick C1 protein and a photoactivatable cholesterol analog requires a functional sterol-sensing domain

26 August 2024

94

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Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol

26 August 2024

96

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Structure and lipid transport mechanism of a StAR-related domain

26 August 2024

97

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Cholesterol binding at the cholesterol recognition/ interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide

26 August 2024

98

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Cholesterol interaction with proteins that partition into membrane domains: an overview

26 August 2024

99

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A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

26 August 2024

100

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Purified NPC1 protein. I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein.

26 August 2024

101

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Identification of a conserved domain of the HIV-1 transmembrane protein gp41 which interacts with cholesteryl groups

26 August 2024

102

1 reference

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Sigma-1 receptors bind cholesterol and remodel lipid rafts in breast cancer cell lines

26 August 2024

103

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Protein Lipid Overlay Assay

26 August 2024

104

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Intracellular cholesterol transporter StarD4 binds free cholesterol and increases cholesteryl ester formation

26 August 2024

105

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Direct binding of cholesterol to the purified membrane region of SCAP: mechanism for a sterol-sensing domain

26 August 2024

106

1 reference

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Physical properties of the fluorescent sterol probe dehydroergosterol

26 August 2024

107

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Recent advances in membrane cholesterol domain dynamics and intracellular cholesterol trafficking

26 August 2024

108

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Spontaneous and protein-mediated sterol transfer between intracellular membranes

26 August 2024

109

1 reference

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The fluorescent cholesterol analog dehydroergosterol induces liquid-ordered domains in model membranes.

26 August 2024

110

1 reference

https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

High density lipoprotein-mediated cholesterol uptake and targeting to lipid droplets in intact L-cell fibroblasts. A single- and multiphoton fluorescence approach

26 August 2024

111

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Cholesterol distribution in living cells: fluorescence imaging using dehydroergosterol as a fluorescent cholesterol analog

26 August 2024

112

1 reference

https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Vesicular and non-vesicular sterol transport in living cells. The endocytic recycling compartment is a major sterol storage organelle

26 August 2024

113

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Rapid nonvesicular transport of sterol between the plasma membrane domains of polarized hepatic cells

26 August 2024

114

1 reference

https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Fluorescence and multiphoton imaging resolve unique structural forms of sterol in membranes of living cells

26 August 2024

115

1 reference

https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Different transport routes for high density lipoprotein and its associated free sterol in polarized hepatic cells

26 August 2024

116

1 reference

https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Structural analysis of sterol distributions in the plasma membrane of living cells

26 August 2024

117

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Plasma membrane sterol distribution resembles the surface topography of living cells

26 August 2024

118

1 reference

https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Sterol, protein and lipid trafficking in Chinese hamster ovary cells with Niemann-Pick type C1 defect

26 August 2024

119

1 reference

https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Sterols are mainly in the cytoplasmic leaflet of the plasma membrane and the endocytic recycling compartment in CHO cells

26 August 2024

120

1 reference

https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Selective visualization of fluorescent sterols in Caenorhabditis elegans by bleach-rate-based image segmentation.

26 August 2024

121

1 reference

https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Characterization of fluorescent sterol binding to purified human NPC1.

26 August 2024

124

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A fluorescence and radiolabel study of sterol exchange between membranes

26 August 2024

127

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The potential of fluorescent and spin-labeled steroid analogs to mimic natural cholesterol

26 August 2024

128

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delta 5,7,9(11)-Cholestatrien-3 beta-ol: a fluorescent cholesterol analogue

26 August 2024

129

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Fluorescence properties of cholestatrienol in phosphatidylcholine bilayer vesicles

26 August 2024

130

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Organization and interaction of cholesterol and phosphatidylcholine in model bilayer membranes

26 August 2024

131

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Cholesterol dynamics in membranes

26 August 2024

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Domain formation and stability in complex lipid bilayers as reported by cholestatrienol

26 August 2024

133

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Sterol affinity for bilayer membranes is affected by their ceramide content and the ceramide chain length

26 August 2024

134

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Effect of anti-tumor ether lipids on ordered domains in model membranes

26 August 2024

135

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Uptake of cholesterol by the retina occurs primarily via a low density lipoprotein receptor-mediated process

26 August 2024

136

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Chemistry and biology of N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)-labeled lipids: fluorescent probes of biological and model membranes

26 August 2024

137

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Exclusion of a cholesterol analog from the cholesterol-rich phase in model membranes.

26 August 2024

138

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Parallax method for direct measurement of membrane penetration depth utilizing fluorescence quenching by spin-labeled phospholipids

26 August 2024

139

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Spectroscopic and ionization properties of N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)-labeled lipids in model membranes

26 August 2024

140

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Membrane organization at low cholesterol concentrations: a study using 7-nitrobenz-2-oxa-1,3-diazol-4-yl-labeled cholesterol.

26 August 2024

141

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Cholesterol organization in membranes at low concentrations: effects of curvature stress and membrane thickness

26 August 2024

142

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Transmembrane distribution of sterol in the human erythrocyte

26 August 2024

143

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Fluorescence assay for phospholipid membrane asymmetry

26 August 2024

144

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Protein-disulfide isomerase is a component of an NBD-cholesterol monomerizing protein complex from hamster small intestine

26 August 2024

145

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Cholesterol deprivation affects the fluorescence properties of a ceramide analog at the Golgi apparatus of living cells

26 August 2024

146

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Lipid binding to sterol carrier protein-2 is inhibited by ethanol

26 August 2024

147

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Steroidogenic acute regulatory protein binds cholesterol and modulates mitochondrial membrane sterol domain dynamics

26 August 2024

148

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Sterol carrier protein-2 alters high density lipoprotein-mediated cholesterol efflux

26 August 2024

149

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Identification of ACAT1- and ACAT2-specific inhibitors using a novel, cell-based fluorescence assay: individual ACAT uniqueness

26 August 2024

151

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HDL-mediated cholesterol uptake and targeting to lipid droplets in adipocytes

26 August 2024

152

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NBD-cholesterol probes to track cholesterol distribution in model membranes

26 August 2024

153

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A novel fluorescent ceramide analogue for studying membrane traffic in animal cells: accumulation at the Golgi apparatus results in altered spectral properties of the sphingolipid precursor

26 August 2024

154

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Use of Bodipy-labeled sphingolipid and cholesterol analogs to examine membrane microdomains in cells

26 August 2024

155

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

First synthesis of free cholesterol-BODIPY conjugates

26 August 2024

156

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26 August 2024

157

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Synthesis and spectral properties of cholesterol- and FTY720-containing boron dipyrromethene dyes

26 August 2024

158

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Membrane fluidity and lipid order in ternary giant unilamellar vesicles using a new bodipy-cholesterol derivative

26 August 2024

159

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BODIPY-cholesterol: a new tool to visualize sterol trafficking in living cells and organisms

26 August 2024

160

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Transport of plasma membrane-derived cholesterol and the function of Niemann-Pick C1 Protein

26 August 2024

161

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Behavior of a photoactivatable analog of cholesterol, 6-photocholesterol, in model membranes

26 August 2024

162

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Orientation and dynamics of a novel fluorescent cholesterol analogue in membranes of varying phase.

26 August 2024

163

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Intracellular cholesterol transport.

26 August 2024

165

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Fluorescent sterols monitor cell penetrating peptide Pep-1 mediated uptake and intracellular targeting of cargo protein in living cells

26 August 2024

166

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Use of dansyl-cholestanol as a probe of cholesterol behavior in membranes of living cells

26 August 2024

167

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Cholesterol derivative of poly(ethylene glycol) inhibits clathrin-independent, but not clathrin-dependent endocytosis

26 August 2024

168

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Distribution and transport of cholesterol-rich membrane domains monitored by a membrane-impermeant fluorescent polyethylene glycol-derivatized cholesterol

26 August 2024

169

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Cholesterol controls lipid endocytosis through Rab11.

26 August 2024

170

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Investigation on lipid asymmetry using lipid probes: Comparison between spin-labeled lipids and fluorescent lipids

26 August 2024

171

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Inhibition of cholesterol synthesis in cultured cells by 25-azidonorcholesterol

26 August 2024

173

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Interactions of a photosensitive analog of cholesterol with hydroxymethylglutaryl-CoA reductase (NADPH) and acyl-CoA:cholesterol acyltransferase

26 August 2024

174

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Chemical studies on the structure of human serum high-density lipoprotein (HDL). Photochemical crosslinking of azido-labelled lipids in HDL.

26 August 2024

176

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Syntheses of phosphatidylcholines, sphingomyelins and cholesterol substituted with azido fatty acids. Photocrosslinking with nearest neighbouring lipids in liposomes chemical and mass spectroscopic proof

26 August 2024

177

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Identification of subunits of acetylcholine receptor that interact with a cholesterol photoaffinity probe

26 August 2024

181

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Rates of spontaneous exchange of synthetic radiolabeled sterols between lipid vesicles

26 August 2024

182

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Effects of lipids on acetylcholine receptor. Essential need of cholesterol for maintenance of agonist-induced state transitions in lipid vesicles

26 August 2024

183

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Labeling of the nicotinic acetylcholine receptor by a photoactivatable steroid probe: effects of cholesterol and cholinergic ligands

26 August 2024

184

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Identifying the cholesterol binding domain in the nicotinic acetylcholine receptor with [125I]azido-cholesterol

26 August 2024

185

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Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles

26 August 2024

191

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Distribution and transport of cholesterol in Caenorhabditis elegans.

26 August 2024

192

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Functional characterization of the MENTAL domain

26 August 2024

193

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Assembly of myelin by association of proteolipid protein with cholesterol- and galactosylceramide-rich membrane domains

26 August 2024

194

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Perturbed interactions of mutant proteolipid protein/DM20 with cholesterol and lipid rafts in oligodendroglia: implications for dysmyelination in spastic paraplegia.

26 August 2024

195

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A physical and functional link between cholesterol and tetraspanins

26 August 2024

196

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Intestinal cholesterol absorption: identification of different binding proteins for cholesterol and cholesterol absorption inhibitors in the enterocyte brush border membrane

26 August 2024

197

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Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs

26 August 2024

198

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Cholesterol interaction with the related steroidogenic acute regulatory lipid-transfer (START) domains of StAR (STARD1) and MLN64 (STARD3).

26 August 2024

199

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Differential Cholesterol Binding by Class II Fusion Proteins Determines Membrane Fusion Properties

26 August 2024

200

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Cholesterol interacts with transmembrane alpha-helices M1, M3, and M4 of the Torpedo nicotinic acetylcholine receptor: photolabeling studies using [3H]Azicholesterol

26 August 2024

201

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Protein-protein interactions mediate mitochondrial cholesterol transport and steroid biosynthesis

26 August 2024

203

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One-step synthesis of biotinyl photoprobes from unprotected carbohydrates

26 August 2024

204

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Novel bifunctional probe for radioisotope-free photoaffinity labeling: compact structure comprised of photospecific ligand ligation and detectable tag anchoring units

26 August 2024

205

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Photocrosslinking and click chemistry enable the specific detection of proteins interacting with phospholipids at the membrane interface

26 August 2024

206

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Protein-lipid interactions: paparazzi hunting for snap-shots.

26 August 2024

207

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Methionine acts as a "magnet" in photoaffinity crosslinking experiments

26 August 2024

209

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Benzophenone-containing cholesterol surrogates: synthesis and biological evaluation

26 August 2024

210

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Sterol efflux to apolipoprotein A-I originates from caveolin-rich microdomains and potentiates PDGF-dependent protein kinase activity

26 August 2024

211

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Preparation and biochemical evaluation of fluorenone-containing lipid analogs

26 August 2024

212

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Cholesterol binding does not predict activity of the steroidogenic acute regulatory protein, StAR.

26 August 2024

213

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

Human StarD5, a cytosolic StAR-related lipid binding protein

26 August 2024

214

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Characterization of the cholesterol recognition amino acid consensus sequence of the peripheral-type benzodiazepine receptor

26 August 2024

215

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https://api.crossref.org/works/10.1016/J.STEROIDS.2010.11.001

26 August 2024

Identifiers

1 reference

23 August 2017

1 reference