Using NMR to study fast dynamics in proteins: methods and applications (Q37798994)

23 August 2017

Using NMR to study fast dynamics in proteins: methods and applications (English)

1 reference

23 August 2017

Paul J. Sapienza

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:20933469

30 July 2024

Andrew L. Lee

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:20933469

30 July 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20933469

30 July 2024

publication date

8 October 2010

1 reference

PMC publication ID

3001252

full work available at URL

23 August 2017

https://cdr.lib.unc.edu/downloads/5425kh75f

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:20933469

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20933469/?tool=EBI

30 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:20933469

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20933469/pdf/?tool=EBI

30 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:20933469

https://europepmc.org/articles/PMC3001252

30 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:20933469

https://europepmc.org/articles/PMC3001252?pdf=render

30 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:20933469

https://doi.org/10.1016/j.coph.2010.09.006

30 July 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:20933469

https://api.elsevier.com/content/article/PII:S147148921000144X?httpAccept=text/xml

30 July 2024

1 reference

10.1016/J.COPH.2010.09.006

Crossref

DOI

https://api.crossref.org/works/10.1016/J.COPH.2010.09.006

https://api.elsevier.com/content/article/PII:S147148921000144X?httpAccept=text/plain

30 July 2024

1 reference

10.1016/J.COPH.2010.09.006

Crossref

DOI

https://api.crossref.org/works/10.1016/J.COPH.2010.09.006

Current Opinion in Pharmacology

30 July 2024

published in

1 reference

23 August 2017

10

1 reference

23 August 2017

6

1 reference

23 August 2017

723-730

1 reference

Experimental approaches for NMR studies of side-chain dynamics in high-molecular-weight proteins

23 August 2017

1 reference

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Beneficial effects of combining a type II ATP competitive inhibitor with an allosteric competitive inhibitor of BCR-ABL for the treatment of imatinib-sensitive and imatinib-resistant CML.

6 September 2017

1 reference

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The role of conformational entropy in molecular recognition by calmodulin

6 September 2017

1 reference

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Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors

6 September 2017

1 reference

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Absolute Single-Molecule Entropies from Quasi-Harmonic Analysis of Microsecond Molecular Dynamics: Correction Terms and Convergence Properties

6 September 2017

1 reference

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Hidden dynamic allostery in a PDZ domain.

6 September 2017

1 reference

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Dynamically driven ligand selectivity in cyclic nucleotide binding domains

6 September 2017

1 reference

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Binding of small-molecule ligands to proteins: "what you see" is not always "what you get".

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Managing protein flexibility in docking and its applications

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Flexible ligand docking to multiple receptor conformations: a practical alternative

6 September 2017

1 reference

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A hierarchy of timescales in protein dynamics is linked to enzyme catalysis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Conformational entropy in molecular recognition by proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Molecular evolution of affinity and flexibility in the immune system

6 September 2017

1 reference

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Antibody evolution constrains conformational heterogeneity by tailoring protein dynamics

6 September 2017

1 reference

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Dynamically driven protein allostery.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Conformational dynamics of calmodulin in complex with the calmodulin-dependent kinase kinase alpha calmodulin-binding domain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Characterization of the fast dynamics of protein amino acid side chains using NMR relaxation in solution

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Fast time scale dynamics of protein backbones: NMR relaxation methods, applications, and functional consequences

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

New tools provide new insights in NMR studies of protein dynamics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Simultaneous determination of protein structure and dynamics.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

The structural and dynamic basis of Ets-1 DNA binding autoinhibition.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Prediction of methyl-side chain dynamics in proteins.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Deuterium spin probes of side-chain dynamics in proteins. 1. Measurement of five relaxation rates per deuteron in (13)C-labeled and fractionally (2)H-enriched proteins in solution

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Rapid structural fluctuations of the free HIV protease flaps in solution: relationship to crystal structures and comparison with predictions of dynamics calculations

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Nuclear magnetic resonance methods for quantifying microsecond-to-millisecond motions in biological macromolecules

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Efficient analysis of macromolecular rotational diffusion from heteronuclear relaxation data

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Insights into the local residual entropy of proteins provided by NMR relaxation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Contributions to conformational entropy arising from bond vector fluctuations measured from NMR-derived order parameters: application to protein folding

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Backbone dynamics of Escherichia coli ribonuclease HI: correlations with structure and function in an active enzyme

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Quantitative lid dynamics of MDM2 reveals differential ligand binding modes of the p53-binding cleft.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Backbone dynamics of calmodulin studied by 15N relaxation using inverse detected two-dimensional NMR spectroscopy: the central helix is flexible.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Dynamic activation of an allosteric regulatory protein.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

A dictionary for protein side-chain entropies from NMR order parameters.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

(Thermo)dynamic role of receptor flexibility, entropy, and motional correlation in protein-ligand binding

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Relating side-chain mobility in proteins to rotameric transitions: insights from molecular dynamics simulations and NMR.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001252

An effective method for the discrimination of motional anisotropy and chemical exchange

1 September 2018

1 reference

12 December 2020

Allostery without conformational change. A plausible model

1 reference

12 December 2020

Insights into the mobility of methyl-bearing side chains in proteins from (3)J(CC) and (3)J(CN) couplings

1 reference

12 December 2020

The use of model selection in the model-free analysis of protein dynamics

1 reference

12 December 2020

Sequence-specific dynamics modulate recognition specificity in WW domains

1 reference

12 December 2020

Characterization of the backbone and side chain dynamics of the CaM-CaMKIp complex reveals microscopic contributions to protein conformational entropy

1 reference

12 December 2020

10.1016/J.COPH.2010.09.006

Identifiers

DOI

1 reference

23 August 2017

1 reference

PMC publication ID

3001252

23 August 2017

1 reference

PMC publication ID

3001252