The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis (Q37798162)

23 August 2017

title

The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis (English)

1 reference

23 August 2017

0 references

1 reference

Jérémie Sellam

1

1 reference

23 August 2017

Francis Berenbaum

series ordinal

2

1 reference

23 August 2017

language of work or name

English

0 references

publication date

5 October 2010

1 reference

Nature Reviews Rheumatology

23 August 2017

published in

1 reference

23 August 2017

volume

6

1 reference

23 August 2017

issue

11

1 reference

23 August 2017

page(s)

625-635

1 reference

Proposed scoring system for assessing synovial membrane abnormalities at arthroscopy in knee osteoarthritis

23 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Specificity of T cells in synovial fluid: high frequencies of CD8( ) T cells that are specific for certain viral epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Synovial fluid cell analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Current concepts in the pathogenesis of osteoarthritis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Intraarticular variation in synovitis. Local macroscopic and microscopic signs of inflammatory activity are significantly correlated

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Synovial tissue inflammation in early and late osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Macroscopic and microscopic features of synovial membrane inflammation in the osteoarthritic knee: correlating magnetic resonance imaging findings with disease severity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Usefulness of high resolution US in the evaluation of effusion in osteoarthritic first carpometacarpal joint

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Synovitis: a potential predictive factor of structural progression of medial tibiofemoral knee osteoarthritis -- results of a 1 year longitudinal arthroscopic study in 422 patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Factors affecting radiographic progression of knee osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Synovial thickening detected by MR imaging in osteoarthritis of the knee confirmed by biopsy as synovitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Synovitis detected on magnetic resonance imaging and its relation to pain and cartilage loss in knee osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Tibiofemoral joint osteoarthritis: risk factors for MR-depicted fast cartilage loss over a 30-month period in the multicenter osteoarthritis study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

A new non-invasive method to assess synovitis severity in relation to symptoms and cartilage volume loss in knee osteoarthritis patients using MRI

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Indications of inflammation visualized by ultrasound in osteoarthritis of the knee

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Long-term sonographic follow-up of rheumatoid and psoriatic proliferative knee joint synovitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Correlation of power Doppler sonography with vascularity of the synovial tissue of the knee joint in patients with osteoarthritis and rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

EULAR report on the use of ultrasonography in painful knee osteoarthritis. Part 1: prevalence of inflammation in osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

An ultrasonographic study of osteoarthritis of the hand: Synovitis and its relationship to structural pathology and symptoms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Clinical and ultrasonographic predictors of joint replacement for knee osteoarthritis: results from a large, 3-year, prospective EULAR study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Arthroscopic evaluation of potential structure-modifying drug in osteoarthritis of the knee. A multicenter, randomized, double-blind comparison of tenidap sodium vs piroxicam.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Elevated high-sensitivity C-reactive protein levels are associated with local inflammatory findings in patients with osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Increased serum C reactive protein may reflect events that precede radiographic progression in osteoarthritis of the knee

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Severity and extent of osteoarthritis and low grade systemic inflammation as assessed by high sensitivity C reactive protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

C-reactive protein, metabolic syndrome and incidence of severe hip and knee osteoarthritis. A population-based cohort study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: The Chingford Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Serum levels of YKL-40 and C reactive protein in patients with hip osteoarthritis and healthy subjects: a cross sectional study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Monitoring cartilage turnover

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Significant increases in serum and plasma concentrations of matrix metalloproteinases 3 and 9 in patients with rapidly destructive osteoarthritis of the hip

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

UK community prevalence of knee chondrocalcinosis: evidence that correlation with osteoarthritis is through a shared association with osteophyte.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Angiogenesis in the synovium and at the osteochondral junction in osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Angiogenesis in osteoarthritis and spondylosis: successful repair with undesirable outcomes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Intra-articular variation of synovial changes in knee arthritis: biopsy study comparing changes in patellofemoral synovium and the medial tibiofemoral synovium

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Presence of pannus-like tissue on osteoarthritic cartilage and its histological character

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

The contribution of the synovium, synovial derived inflammatory cytokines and neuropeptides to the pathogenesis of osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Characterization of cells from pannus-like tissue over articular cartilage of advanced osteoarthritis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

T-cell mediated inflammatory pathway in osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Inflammation and angiogenesis in osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

The role of T cells in the pathogenesis of osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Restricted heterogeneity of T cell receptor transcripts in rheumatoid synovium

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Cellular immune response toward human articular chondrocytes. T cell reactivities against chondrocyte and fibroblast membranes in destructive joint diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Enhanced T cell proliferative response to type II collagen and synthetic peptide CII (255-274) in patients with rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Use of soluble peptide-DR4 tetramers to detect synovial T cells specific for cartilage antigens in patients with rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Autoantibody specificities of immune complexes sequestered in articular cartilage of patients with rheumatoid arthritis and osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Immunohistochemical analysis of synovial membranes from inflammatory and non-inflammatory arthritides: scarcity of CD5 positive B cells and IL2 receptor bearing T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Lymphoid chemokine B cell-attracting chemokine-1 (CXCL13) is expressed in germinal center of ectopic lymphoid follicles within the synovium of chronic arthritis patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

The deposition of immunoglobulins and complement in osteoarthritic cartilage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Expression of toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-gamma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Osteoarthritis, angiogenesis and inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Cytokine expression in synovial membranes of patients with rheumatoid arthritis and osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Interleukin-8, interleukin-10, intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 expression levels are higher in synovial tissue from patients with rheumatoid arthritis than in osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Interleukin-17, a regulator of angiogenic factor release by synovial fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Contribution of interleukin 17 to human cartilage degradation and synovial inflammation in osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Local cytokine profiles in knee osteoarthritis: elevated synovial fluid interleukin-15 differentiates early from end-stage disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Pre-B cell colony-enhancing factor/visfatin, a new marker of inflammation in rheumatoid arthritis with proinflammatory and matrix-degrading activities

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Differential distribution of adipokines between serum and synovial fluid in patients with osteoarthritis. Contribution of joint tissues to their articular production.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Neurovascular invasion at the osteochondral junction and in osteophytes in osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

The sources of pain in knee osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Neuropeptides in experimental and degenerative arthritis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Knee osteoarthritis: a role for bradykinin?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Substance P-, calcitonin gene-related peptide-and C-flanking peptide of neuropeptide Y-immunoreactive fibres are present in normal synovium but depleted in patients with rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Substance P activation of rheumatoid synoviocytes: neural pathway in pathogenesis of arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Beta-endorphin, Met-enkephalin and corresponding opioid receptors within synovium of patients with joint trauma, osteoarthritis and rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Nerve growth factor in rheumatic diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

The regulatory role of nerve growth factor and its receptor system in fibroblast-like synovial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

In vitro release of prostaglandins and leukotrienes from synovial tissue, cartilage, and bone in degenerative joint diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis: involvement of matrix metalloproteinase 3

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Pro-MMP-9 is a specific macrophage product and is activated by osteoarthritic chondrocytes via MMP-3 or a MT1-MMP/MMP-13 cascade

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Synovial fluid macrophages are capable of osteoclast formation and resorption

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Mature and activated osteoclasts exist in the synovium of rapidly destructive coxarthrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Anti-inflammatory activity of chondroitin sulfate

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Targeted therapies in osteoarthritis: a systematic review of the trials on www.clinicaltrials.gov

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Probing the binding mechanism and affinity of tanezumab, a recombinant humanized anti-NGF monoclonal antibody, using a repertoire of biosensors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Pathobiology of osteoarthritis: pathomechanisms and potential therapeutic targets

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Anticytokine therapy for osteoarthritis: evidence to date

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Intraarticular injection of anakinra in osteoarthritis of the knee: a multicenter, randomized, double-blind, placebo-controlled study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Interleukin-6 and high mobility group box protein-1 in synovial membranes and osteochondral fragments in equine osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Mechanical loading highly increases IL-6 production and decreases OPG expression by osteoblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

Can ultrasonography improve on radiographic assessment in osteoarthritis of the hands? A comparison between radiographic and ultrasonographic detected pathology.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.159

The C-reactive protein but not erythrocyte sedimentation rate is associated with clinical severity in patients with osteoarthritis of the knee or hip

31 March 2020

1 reference

12 December 2020

Low-level increases in serum C-reactive protein are present in early osteoarthritis of the knee and predict progressive disease

1 reference

12 December 2020

Osteoarthritis: a tale of three tissues.

1 reference

12 December 2020

High resolution ultrasonography in detection of bone erosions in patients with hand osteoarthritis

1 reference

12 December 2020

Osteoarthritis and rheumatoid arthritis pannus have similar qualitative metabolic characteristics and pro-inflammatory cytokine response.

1 reference

12 December 2020

Arthroscopic evaluation of post-traumatic patellofemoral chondropathy

1 reference

12 December 2020

Characterisation of equine matrix metalloproteinase 2 and 9; and identification of the cellular sources of these enzymes in joints

1 reference

12 December 2020

Human synovial fibroblasts coexpress IL-1 receptor type I and type II mRNA. The increased level of the IL-1 receptor in osteoarthritic cells is related to an increased level of the type I receptor

1 reference

12 December 2020

Magnetic resonance imaging-determined synovial membrane and joint effusion volumes in rheumatoid arthritis and osteoarthritis: comparison with the macroscopic and microscopic appearance of the synovium

1 reference

12 December 2020

T cells and T-cell cytokine transcripts in the synovial membrane in patients with osteoarthritis

1 reference

12 December 2020

Osteoarthritic synovial fibroblasts possess an increased level of tumor necrosis factor-receptor 55 (TNF-R55) that mediates biological activation by TNF-alpha

1 reference

12 December 2020

Synovial membrane inflammation and cytokine production in patients with early osteoarthritis

1 reference

12 December 2020

Osteoarthritis in 2007.

1 reference

12 December 2020

Synovial inflammation in patients with early osteoarthritis of the knee

1 reference

12 December 2020

Focally regulated endothelial proliferation and cell death in human synovium

1 reference

12 December 2020

Efficacy and role of topical treatment of gonarthrosis

1 reference

12 December 2020

Localization of matrix metalloproteinase 3 (stromelysin) in osteoarthritic cartilage and synovium

1 reference

12 December 2020

Decreased expression of the CD3zeta chain in T cells infiltrating the synovial membrane of patients with osteoarthritis.

1 reference

12 December 2020

Ultrasound imaging for the rheumatologist VIII. Ultrasound imaging in osteoarthritis.

1 reference

12 December 2020

Cytokines and their role in the pathophysiology of osteoarthritis

1 reference

12 December 2020

Pathophysiology of joint pain

1 reference

12 December 2020

The role of inflammatory mediators on nociception and pain in arthritis

1 reference

12 December 2020

Distributional changes in substance P nociceptive fiber patterns in naturally osteoarthritic articulations

1 reference

12 December 2020

Soluble interleukin 6 (IL-6) receptor and IL-6 levels in serum and synovial fluid of patients with different arthropathies

1 reference

12 December 2020

Vascular endothelial growth factor levels in the serum and synovial fluid of patients with rheumatoid arthritis

1 reference

12 December 2020

Vascular endothelial growth factor. A cytokine modulating endothelial function in rheumatoid arthritis

1 reference

12 December 2020

Immunolocalization of endothelial and leukocyte adhesion molecules in human rheumatoid and osteoarthritic synovial tissues

1 reference

12 December 2020

Clinical assessment of osteoarthritis in clinical trials

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRRHEUM.2010.159

1 reference

Dimensions Publication ID

23 August 2017

1042329500

0 references

1 reference