DNA Methylation Profiling in Acute Myeloid Leukemia: From Recent Technological Advances to Biological and Clinical Insights (Q37797467)

23 August 2017

title

DNA methylation profiling in acute myeloid leukemia: from recent technological advances to biological and clinical insights (English)

1 reference

23 August 2017

DNA Methylation Profiling in Acute Myeloid Leukemia: From Recent Technological Advances to Biological and Clinical Insights (English)

1 reference

27 July 2024

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acute myeloid leukemia

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4

Lars Bullinger

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:20919827

27 July 2024

author name string

Rainer Claus

1

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23 August 2017

Christoph Plass

2

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23 August 2017

Scott A. Armstrong

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:20919827

27 July 2024

language of work or name

English

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publication date

1 September 2010

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full work available at URL

23 August 2017

http://www.futuremedicine.com/doi/abs/10.2217/fon.10.110

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:20919827

https://www.tandfonline.com/doi/pdf/10.2217/fon.10.110

27 July 2024

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27 July 2024

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23 August 2017

volume

6

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23 August 2017

issue

9

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23 August 2017

page(s)

1415-1431

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Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

23 August 2017

cites work

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21 January 2018

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Impact of new prognostic markers in treatment decisions in acute myeloid leukemia

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Identification of acquired copy number alterations and uniparental disomies in cytogenetically normal acute myeloid leukemia using high-resolution single-nucleotide polymorphism analysis

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A decade of genome-wide gene expression profiling in acute myeloid leukemia: flashback and prospects

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Epigenetic germline inheritance

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The epigenomics of cancer

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

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Large-scale structure of genomic methylation patterns

21 January 2018

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Comprehensive analysis of CpG islands in human chromosomes 21 and 22

21 January 2018

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Association of tissue-specific differentially methylated regions (TDMs) with differential gene expression

21 January 2018

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Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells

21 January 2018

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

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Epigenetic reprogramming in mammals

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Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

21 January 2018

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5-Methylcytosine DNA glycosylase participates in the genome-wide loss of DNA methylation occurring during mouse myoblast differentiation

21 January 2018

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Establishing, maintaining and modifying DNA methylation patterns in plants and animals

21 January 2018

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The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

21 January 2018

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

21 January 2018

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Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation

21 January 2018

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Sin meets NuRD and other tails of repression.

21 January 2018

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Genomic DNA methylation: the mark and its mediators

21 January 2018

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Genome-wide evolutionary analysis of eukaryotic DNA methylation.

21 January 2018

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Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription.

21 January 2018

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Rasgrf1 imprinting is regulated by a CTCF-dependent methylation-sensitive enhancer blocker

21 January 2018

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Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

21 January 2018

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CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

21 January 2018

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High sensitivity mapping of methylated cytosines

21 January 2018

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Ultradeep bisulfite sequencing analysis of DNA methylation patterns in multiple gene promoters by 454 sequencing.

21 January 2018

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Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

21 January 2018

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MethyLight: a high-throughput assay to measure DNA methylation

21 January 2018

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COBRA: a sensitive and quantitative DNA methylation assay

21 January 2018

1 reference

Quantification of DNA methylation in electrofluidics chips (Bio-COBRA).

21 January 2018

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Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry

21 January 2018

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The study of aberrant methylation in cancer via restriction landmark genomic scanning.

21 January 2018

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Restriction landmark genomic scanning method and its various applications

21 January 2018

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Cancer epigenomics: DNA methylomes and histone-modification maps

21 January 2018

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Principles and challenges of genomewide DNA methylation analysis

21 January 2018

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Comparative isoschizomer profiling of cytosine methylation: the HELP assay

21 January 2018

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Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis

21 January 2018

1 reference

Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells

21 January 2018

1 reference

Genome-wide profiling of CpG methylation identifies novel targets of aberrant hypermethylation in myeloid leukemia

21 January 2018

1 reference

MIRA-assisted microarray analysis, a new technology for the determination of DNA methylation patterns, identifies frequent methylation of homeodomain-containing genes in lung cancer cells

21 January 2018

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Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells

21 January 2018

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Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming

21 January 2018

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A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis

21 January 2018

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MEDME: an experimental and analytical methodology for the estimation of DNA methylation levels based on microarray derived MeDIP-enrichment.

21 January 2018

1 reference

Human DNA methylomes at base resolution show widespread epigenomic differences

21 January 2018

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Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

21 January 2018

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Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells

21 January 2018

1 reference

Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia

21 January 2018

1 reference

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

21 January 2018

1 reference

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

21 January 2018

1 reference

The 5-methylcytosine content of DNA from human tumors

21 January 2018

1 reference

The 5-methylcytosine content of highly repeated sequences in human DNA.

21 January 2018

1 reference

Hypomethylation-linked activation of PAX2 mediates tamoxifen-stimulated endometrial carcinogenesis

21 January 2018

1 reference

The death-associated protein kinases: structure, function, and beyond

21 January 2018

1 reference

CpG island methylation and expression of the secreted frizzled-related protein gene family in chronic lymphocytic leukemia

21 January 2018

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Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemia

21 January 2018

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Mutation and cancer: statistical study of retinoblastoma

21 January 2018

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Chromosome 5q deletion and epigenetic suppression of the gene encoding alpha-catenin (CTNNA1) in myeloid cell transformation

21 January 2018

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Clinical implications of aberrant DNA methylation patterns in acute myelogenous leukemia

21 January 2018

1 reference

Epigenetic modification of CCAAT/enhancer binding protein alpha expression in acute myeloid leukemia

21 January 2018

1 reference

The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemia

21 January 2018

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Methylation of the hMLH1 promoter and its association with microsatellite instability in acute myeloid leukemia.

21 January 2018

1 reference

Aberrant methylation of DAP-kinase in therapy-related acute myeloid leukemia and myelodysplastic syndromes

21 January 2018

1 reference

Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia.

21 January 2018

1 reference

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

21 January 2018

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Aberrant DNA methylation is a dominant mechanism in MDS progression to AML.

21 January 2018

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MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation

21 January 2018

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DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia.

21 January 2018

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Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia

21 January 2018

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Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia

21 January 2018

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Quantitative DNA methylation predicts survival in adult acute myeloid leukemia

21 January 2018

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DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes

21 January 2018

1 reference

Gene-specific and global methylation patterns predict outcome in patients with acute myeloid leukemia.

21 January 2018

1 reference

Epigenetic treatment of hematopoietic malignancies: in vivo targets of demethylating agents

21 January 2018

1 reference

The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells

21 January 2018

1 reference

CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells

21 January 2018

1 reference

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

21 January 2018

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Interplay of RUNX1/MTG8 and DNA methyltransferase 1 in acute myeloid leukemia.

21 January 2018

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Chromatin maps, histone modifications and leukemia.

21 January 2018

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Stem cell chromatin patterns: an instructive mechanism for DNA hypermethylation?

21 January 2018

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A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

21 January 2018

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Epigenetic stem cell signature in cancer

21 January 2018

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Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

21 January 2018

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Chromatin modifications induced by PML-RARalpha repress critical targets in leukemogenesis as analyzed by ChIP-Chip

21 January 2018

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H3K79 methylation profiles define murine and human MLL-AF4 leukemias

21 January 2018

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The leukemic stem cell niche: current concepts and therapeutic opportunities

21 January 2018

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A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands

21 January 2018

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Whole-genome genotyping with the single-base extension assay

21 January 2018

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Novel regions of acquired uniparental disomy discovered in acute myeloid leukemia

21 January 2018

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Gene expression profiling in acute myeloid leukemia

21 January 2018

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Sensitive and quantitative universal Pyrosequencing methylation analysis of CpG sites

27 July 2024

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Analysis and quantification of multiple methylation variable positions in CpG islands by Pyrosequencing

27 July 2024

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MS-FLAG, a novel real-time signal generation method for methylation-specific PCR

27 July 2024

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Methylation profiling of CpG islands in human breast cancer cells

27 July 2024

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Genome-wide profiling of promoter methylation in human

27 July 2024

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Genome-scale DNA methylation maps of pluripotent and differentiated cells

27 July 2024

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High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing

27 July 2024

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Frequent hypomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma.

27 July 2024

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Methylation of p15(INK4b) and E-cadherin genes is independently correlated with poor prognosis in acute myeloid leukemia

27 July 2024

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The estrogen receptor CpG island is methylated in most hematopoietic neoplasms.

27 July 2024

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1 reference

Restriction landmark genome scanning for aberrant methylation in primary refractory and relapsed acute myeloid leukemia; involvement of the WIT-1 gene

27 July 2024

91

1 reference

Methylation of p15 and p16 genes in adult acute leukemia: lack of prognostic significance

27 July 2024

95

1 reference

p15INK4BCpG Island Methylation in Primary Acute Leukemia Is Heterogeneous and Suggests Density as a Critical Factor for Transcriptional Silencing

27 July 2024

96

1 reference

Novel methylation targets in de novo acute myeloid leukemia with prevalence of chromosome 11 loci

27 July 2024

101

1 reference

DOT1L and Histone H3 Lysine79 Methylation as a Therapeutic Target in Mixed Lineage Leukemia.

27 July 2024

123

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GoldenGate assay for DNA methylation profiling

27 July 2024

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27 July 2024

Identifiers

DOI

10.2217/FON.10.110

1 reference

23 August 2017

1 reference