Psoriasis: what we have learned from mouse models (Q37793830)

23 August 2017

title

Psoriasis: what we have learned from mouse models (English)

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23 August 2017

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23 August 2017

Erwin F Wagner

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author name string

Helia B Schonthaler

series ordinal

2

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23 August 2017

Juan Guinea-Viniegra

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3

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23 August 2017

language of work or name

English

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publication date

28 September 2010

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Nature Reviews Rheumatology

23 August 2017

published in

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23 August 2017

volume

6

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23 August 2017

issue

12

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23 August 2017

page(s)

704-714

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Pathogenesis and clinical features of psoriasis

23 August 2017

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Alpha1beta1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis.

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Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis

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Downregulation of TGFβ isoforms and their receptors contributes to keratinocyte hyperproliferation in psoriasis vulgaris

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Future perspectives in the treatment of psoriasis

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31 March 2020

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31 March 2020

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Counter-regulation of interleukin-1alpha (IL-1alpha) and IL-1 receptor antagonist in murine keratinocytes

31 March 2020

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Interleukin-1: A key inflammatory mediator in psoriasis?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Psoriasis-like cutaneous inflammation in mice lacking interleukin-1 receptor antagonist

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Fos and jun proteins are specifically expressed during differentiation of human keratinocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Epidermal JunB represses G-CSF transcription and affects haematopoiesis and bone formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

TNFalpha shedding and epidermal inflammation are controlled by Jun proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Murine psoriasis-like disorder induced by naive CD4 T cells

31 March 2020

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https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Antibodies to complement receptor 3 treat established inflammation in murine models of colitis and a novel model of psoriasiform dermatitis

31 March 2020

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Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha

31 March 2020

1 reference

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JAK3 inhibition significantly attenuates psoriasiform skin inflammation in CD18 mutant PL/J mice.

31 March 2020

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The PKC inhibitor AEB071 may be a therapeutic option for psoriasis.

31 March 2020

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https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

MicroRNAs: novel regulators involved in the pathogenesis of psoriasis?

31 March 2020

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https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

MicroRNAs and potential target interactions in psoriasis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

A cyclosporine-sensitive psoriasis-like disease produced in Tie2 transgenic mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

IL-6 in autoimmune disease and chronic inflammatory proliferative disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Inflammatory skin disease in transgenic mice that express high levels of interleukin 1 alpha in basal epidermis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Interleukin 20: discovery, receptor identification, and role in epidermal function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Suprabasal expression of human amphiregulin in the epidermis of transgenic mice induces a severe, early-onset, psoriasis-like skin pathology: expression of amphiregulin in the basal epidermis is also associated with synovitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: inhibition or stimulation of proliferation depending on the pattern of transgene expression and formation of psoriatic lesions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Transgenic expression of the human amphiregulin gene induces a psoriasis-like phenotype

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Transgenic Mice Expressing IFN-γ in the Epidermis Have Eczema, Hair Hypopigmentation, and Hair Loss

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Expression of activated MEK1 in differentiating epidermal cells is sufficient to generate hyperproliferative and inflammatory skin lesions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

CD8( ) T cell-mediated skin disease in mice lacking IRF-2, the transcriptional attenuator of interferon-alpha/beta signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Cutaneous inflammatory disorder in integrin alphaE (CD103)-deficient mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Crosstalk between Keratinocytes and Adaptive Immune Cells in an IκBα Protein-Mediated Inflammatory Disease of the Skin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRRHEUM.2010.157

Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice

31 March 2020

1 reference

12 December 2020

The status of biologic therapies in the treatment of moderate to severe psoriasis

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12 December 2020

Altered epidermal cell growth control in vivo by inducible expression of transforming growth factor beta 1 in the skin of transgenic mice.

1 reference

12 December 2020

A spontaneous mutation characterized by chronic proliferative dermatitis in C57BL mice

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12 December 2020

IL-1 activity is reduced in psoriatic skin. Decreased IL-1 alpha and increased nonfunctional IL-1 beta

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRRHEUM.2010.157

1 reference

23 August 2017

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