Centrosomes, Polyploidy and Cancer (Q37778011)

23 August 2017

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title

Centrosomes, polyploidy and cancer (English)

1 reference

23 August 2017

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chromosome segregation

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:20687471

17 June 2024

2

Stefan Duensing

1 reference

23 August 2017

1

Anette Duensing

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23 August 2017

language of work or name

English

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publication date

1 January 2010

1 reference

full work available at URL

23 August 2017

2010

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http://link.springer.com/content/pdf/10.1007/978-1-4419-6199-0_6.pdf

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Advances in Experimental Medicine and Biology

17 June 2024

published in

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23 August 2017

volume

676

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23 August 2017

page(s)

93-103

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Preventing re-replication of chromosomal DNA.

23 August 2017

cites work

1 reference

2 April 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/NRM1663

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1126/SCIENCE.282.5393.1497

From polyploidy to aneuploidy, genome instability and cancer

1

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Origins and consequences of centrosome aberrations in human cancers

17 June 2024

2

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Structure and duplication of the centrosome

17 June 2024

4

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Centrosome aberrations: cause or consequence of cancer progression?

17 June 2024

6

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Biochimica et Biophysica Acta

17 June 2024

7

2

M81

S. Duensing

2001

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

17 June 2024

8

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Genetic instability in colorectal cancers

17 June 2024

9

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Triggering p53 after cytokinesis failure

17 June 2024

10

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Cell cycle progression after cleavage failure: mammalian somatic cells do not possess a "tetraploidy checkpoint".

17 June 2024

11

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

17 June 2024

12

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Excessive centrosome abnormalities without ongoing numerical chromosome instability in a Burkitt's lymphoma

17 June 2024

13

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Segmental chromosomal aberrations and centrosome amplifications: pathogenetic mechanisms in Hodgkin and Reed–Sternberg cells of classical Hodgkin's lymphoma?

17 June 2024

14

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle

17 June 2024

15

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

The centrosome in human genetic disease

17 June 2024

18

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Mechanism limiting centrosome duplication to once per cell cycle

17 June 2024

20

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Plk4-induced centriole biogenesis in human cells

17 June 2024

21

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Regulated HsSAS-6 levels ensure formation of a single procentriole per centriole during the centrosome duplication cycle

17 June 2024

22

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Cyclin-dependent kinase 2 is dispensable for normal centrosome duplication but required for oncogene-induced centrosome overduplication

17 June 2024

23

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Centrosome-independent mitotic spindle formation in vertebrates

17 June 2024

24

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Centrosomes enhance the fidelity of cytokinesis in vertebrates and are required for cell cycle progression

17 June 2024

25

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Centrosome duplication and nematodes: recent insights from an old relationship

17 June 2024

26

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Centrosome biogenesis and function: centrosomics brings new understanding

17 June 2024

27

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Centrosome duplication: of rules and licenses

17 June 2024

28

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Centriole assembly in Caenorhabditis elegans

17 June 2024

29

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

17 June 2024

Centrosomes and cancer

30

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

γ-Tubulin is a highly conserved component of the centrosome

17 June 2024

31

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Altered centrosome structure is associated with abnormal mitoses in human breast tumors

17 June 2024

32

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Human papillomavirus infection, centrosome aberration, and genetic stability in cervical lesions

17 June 2024

33

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Amplified centrosomes in breast cancer: a potential indicator of tumor aggressiveness

17 June 2024

34

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Centrosome hyperamplification in head and neck squamous cell carcinoma: a potential phenotypic marker of tumor aggressiveness

17 June 2024

35

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

17 June 2024

Viruses in human cancers

36

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Pathogenesis of human papillomaviruses in differentiating epithelia

17 June 2024

37

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Human papillomavirus immortalization and transformation functions

17 June 2024

38

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Biological activities and molecular targets of the human papillomavirus E7 oncoprotein

17 June 2024

39

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Centriole overduplication through the concurrent formation of multiple daughter centrioles at single maternal templates

17 June 2024

41

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

The formation of basal bodies (centrioles) in the Rhesus monkey oviduct

17 June 2024

42

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

A tentative classification of centrosome abnormalities in cancer

17 June 2024

43

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles

17 June 2024

45

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

p21(Waf1/Cip1) deficiency stimulates centriole overduplication

17 June 2024

46

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Centrosome amplification drives chromosomal instability in breast tumor development

17 June 2024

47

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

17 June 2024

48

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

A role of the mitotic spindle checkpoint in the cellular response to DNA replication stress

17 June 2024

49

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Direct evidence for the role of centrosomally localized p53 in the regulation of centrosome duplication

17 June 2024

50

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Telomere erosion and chromosomal instability in cells expressing the HPV oncogene 16E6.

17 June 2024

52

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Exercising restraints: role of Chk1 in regulating the onset and progression of unperturbed mitosis in vertebrate cells

17 June 2024

53

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Managing the centrosome numbers game: from chaos to stability in cancer cell division

17 June 2024

54

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

17 June 2024

55

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

17 June 2024

56

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Endomitotic megakaryocytes that form a bipolar spindle exhibit cleavage furrow ingression followed by furrow regression

17 June 2024

58

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death.

17 June 2024

60

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Characterization of the p53-Dependent Postmitotic Checkpoint following Spindle Disruption

17 June 2024

61

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cells

17 June 2024

62

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Guilt by association? p53 and the development of aneuploidy in cancer

17 June 2024

63

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Genome-wide genetic analysis of polyploidy in yeast

17 June 2024

64

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Cell fusion: a hidden enemy?

17 June 2024

65

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM.

17 June 2024

67

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Synergistic induction of centrosome hyperamplification by loss of p53 and cyclin E overexpression

17 June 2024

68

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure

17 June 2024

70

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

Excessive centrosome abnormalities without ongoing numerical chromosome instability in a Burkitt's lymphoma

17 June 2024

71

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-6199-0_6

17 June 2024

Identifiers

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1 reference