Gene transfer: how can the biological barriers be overcome? (Q37771877)

22 August 2017

title

Gene transfer: how can the biological barriers be overcome? (English)

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22 August 2017

Marie-Pierre Rols

3

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Jean-Michel Escoffre

object named as

Jean-Michel Escoffre

series ordinal

1

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Justin Teissie

object named as

Justin Teissié

series ordinal

2

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publication date

10 July 2010

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22 August 2017

number of pages

14

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Journal of Membrane Biology

inferred from page(s)

published in

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22 August 2017

volume

236

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22 August 2017

issue

1

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22 August 2017

page(s)

61-74

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Electroporation as a "prime/boost" strategy for naked DNA vaccination against a tumor antigen

22 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007/S00232-010-9275-0

Electroporation enables plasmid vaccines to elicit CD8 T cell responses in the absence of CD4 T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00232-010-9275-0

Distribution of DNA vaccines determines their immunogenicity after intramuscular injection in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00232-010-9275-0

A combination of poloxamers increases gene expression of plasmid DNA in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00232-010-9275-0

Membrane electroporation: a molecular dynamics simulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00232-010-9275-0

Mechanisms of cell membrane electropermeabilization: a minireview of our present (lack of ?) knowledge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00232-010-9275-0

In vivo electroporation and stable transformation of skin cells of newborn mice by plasmid DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00232-010-9275-0

Increased DNA vaccine delivery and immunogenicity by electroporation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00232-010-9275-0

Restoration of dystrophin expression in mdx mice by intravascular injection of naked DNA containing full-length dystrophin cDNA.

21 January 2018

1 reference

12 December 2020

Electroporation and electrophoretic DNA transfer into cells. The effect of DNA interaction with electropores

1 reference

12 December 2020

Extracellular matrix remodelling: the role of matrix metalloproteinases

1 reference

12 December 2020

Magnetically driven plasmid DNA delivery with biodegradable polymeric nanoparticles

1 reference

12 December 2020

In vivo plasmid electroporation induces tumor antigen-specific CD8 T-cell responses and delays tumor growth in a syngeneic mouse melanoma model.

1 reference

12 December 2020

In vivo electrically mediated protein and gene transfer in murine melanoma

1 reference

12 December 2020

Non-viral gene transfer of murine spleen cells achieved by in vivo electroporation.

1 reference

12 December 2020

Uptake, biodistribution, and time course of naked plasmid DNA trafficking after intratumoral in vivo jet injection

1 reference

12 December 2020

Hyaluronidase increases electrogene transfer efficiency in skeletal muscle

1 reference

12 December 2020

High-efficiency gene transfer into skeletal muscle mediated by electric pulses

1 reference

12 December 2020

Direct Cutaneous Gene Delivery in a Human Genetic Skin Disease

1 reference

12 December 2020

Gene therapy progress and prospects: hydrodynamic gene delivery

1 reference

12 December 2020

Two-photon fluorescence correlation microscopy reveals the two-phase nature of transport in tumors

1 reference

12 December 2020

Optimisation of electrotransfer of plasmid into skeletal muscle by pretreatment with hyaluronidase -- increased expression with reduced muscle damage

1 reference

12 December 2020

Hydroporation as the mechanism of hydrodynamic delivery

1 reference

12 December 2020

Nuclear localization signal and cell synchrony enhance gene targeting efficiency in primary fetal fibroblasts

1 reference

12 December 2020

Diverse effects of nanosecond pulsed electric fields on cells and tissues

1 reference

12 December 2020

Model of creation and evolution of stable electropores for DNA delivery

1 reference

12 December 2020

Hyaluronidase enhances recombinant adeno-associated virus (rAAV)-mediated gene transfer in the rat skeletal muscle.

1 reference

12 December 2020

Sonoporation of the minicircle-VEGF(165) for wound healing of diabetic mice

1 reference

12 December 2020

Plasma membrane poration induced by ultrasound exposure: implication for drug delivery.

1 reference

12 December 2020

Novel jet-injection technology for nonviral intratumoral gene transfer in patients with melanoma and breast cancer

1 reference

12 December 2020

Plasmid electrotransfer of eye ciliary muscle: principles and therapeutic efficacy using hTNF-alpha soluble receptor in uveitis

1 reference

12 December 2020

The effect of the histological properties of tumors on transfection efficiency of electrically assisted gene delivery to solid tumors in mice

1 reference

12 December 2020

Suppression of murine mammary carcinoma growth and metastasis by HSVtk/GCV gene therapy using in vivo electroporation

1 reference

12 December 2020

Natural killer cell-mediated ablation of metastatic liver tumors by hydrodynamic injection of IFNalpha gene to mice

1 reference

12 December 2020

Protease pretreatment increases the efficacy of adenovirus-mediated gene therapy for the treatment of an experimental glioblastoma model.

1 reference

12 December 2020

Mammary epithelial cell: influence of extracellular matrix composition and organization during development and tumorigenesis

1 reference

12 December 2020

High-speed photography during ultrasound illustrates potential therapeutic applications of microbubbles.

1 reference

12 December 2020

The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion

1 reference

12 December 2020

The laser method for efficient introduction of foreign DNA into cultured cells

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12 December 2020

Gene transfer into muscle by electroporation in vivo.

1 reference

12 December 2020

Role of extracellular matrix assembly in interstitial transport in solid tumors

1 reference

12 December 2020

Hypothesis: naked plasmid DNA is taken up by cells in vivo by a receptor-mediated process

1 reference

12 December 2020

Electroporation improves the efficacy of DNA vaccines in large animals

1 reference

12 December 2020

The many ways to cross the plasma membrane.

1 reference

12 December 2020

Ultrasound enhances gene delivery of human factor IX plasmid

1 reference

12 December 2020

Direct gene transfer into mouse muscle in vivo

1 reference

12 December 2020

Neoadjuvant gene delivery of feline granulocyte-macrophage colony-stimulating factor using magnetofection for the treatment of feline fibrosarcomas: a phase I trial.

1 reference

12 December 2020

Gene therapy progress and prospects: ultrasound for gene transfer

1 reference

12 December 2020

Tissue-specific and transcription factor-mediated nuclear entry of DNA.

1 reference

12 December 2020

Evaluation of toxicity following electrically mediated interleukin-12 gene delivery in a B16 mouse melanoma model

1 reference

12 December 2020

Role of tumor-host interactions in interstitial diffusion of macromolecules: cranial vs. subcutaneous tumors.

1 reference

12 December 2020

Electroporation-mediated HGF gene transfection protected the kidney against graft injury

1 reference

12 December 2020

Efficient expression of naked dna delivered intraarterially to limb muscles of nonhuman primates

1 reference

12 December 2020

Intramuscular plasmid DNA electrotransfer: biodistribution and degradation

1 reference

12 December 2020

Using magnetic forces to enhance non-viral gene transfer to airway epithelium in vivo

1 reference

12 December 2020

Comparative evaluation of CD8 CTL responses following gene gun immunization targeting the skin with intracutaneous injection of antigen-transduced dendritic cells

1 reference

12 December 2020

Efficient gene transfer into the embryonic mouse brain using in vivo electroporation

1 reference

12 December 2020

Nuclear localisation and pDNA condensation in non-viral gene delivery

1 reference

12 December 2020

Intramuscular SP1017-formulated DNA electrotransfer enhances transgene expression and distributes hHGF to different rat tissues

1 reference

12 December 2020

Variability of naked DNA expression after direct local injection: the influence of the injection speed

1 reference

12 December 2020

Intra-articular electrotransfer of plasmid encoding soluble TNF receptor variants in normal and arthritic mice

1 reference

12 December 2020

Optimisation of intradermal DNA electrotransfer for immunisation

1 reference

12 December 2020

Marked enhancement of direct respiratory tissue transfection by aurintricarboxylic acid

1 reference

12 December 2020

Micromanipulation of endothelial cells: ultrasound-microbubble-cell interaction.

1 reference

12 December 2020

Nonviral jet-injection gene transfer for efficient in vivo cytosine deaminase suicide gene therapy of colon carcinoma

1 reference

12 December 2020

Gene transfer to subdermal tissues via a new gene gun design

1 reference

12 December 2020

Direct gene transfer into donor hearts at the time of harvest

1 reference

12 December 2020

Femtosecond infrared laser-an efficient and safe in vivo gene delivery system for prolonged expression

1 reference

12 December 2020

Nuclear accumulation of plasmid DNA can be enhanced by non-selective gating of the nuclear pore

1 reference

12 December 2020

Metabolic instability of plasmid DNA in the cytosol: a potential barrier to gene transfer

1 reference

12 December 2020

In vivo gene transfer by low-volume jet injection

1 reference

12 December 2020

Particle-mediated cytokine gene therapy leads to antitumor and antimetastatic effects in mouse carcinoma models

1 reference

12 December 2020

Tumor specific ultrasound enhanced gene transfer in vivo with novel liposomal bubbles

1 reference

12 December 2020

Intratumoral low-volume jet-injection for efficient nonviral gene transfer

1 reference

12 December 2020

1 reference

12 December 2020

Gene transfer into somatic tissues by jet injection

1 reference

12 December 2020

Membrane perturbation by an external electric field: a mechanism to permit molecular uptake

1 reference

12 December 2020

Effect of electric field vectoriality on electrically mediated gene delivery in mammalian cells

1 reference

12 December 2020

Microdosimetry for conventional and supra-electroporation in cells with organelles

1 reference

12 December 2020

Cell synchronization effect on mammalian cell permeabilization and gene delivery by electric field

1 reference

12 December 2020

Gene gun bombardment with DNA-coated gold particles is a potential alternative to hydrodynamics-based transfection for delivering genes into superficial hepatocytes

1 reference

12 December 2020

Direct gene transfer into human cultured cells facilitated by laser micropuncture of the cell membrane

1 reference

12 December 2020

Long-lasting in vivo gene silencing by electrotransfer of shRNA expressing plasmid

1 reference

12 December 2020

Treatment of acute myocardial infarction by hepatocyte growth factor gene transfer: the first demonstration of myocardial transfer of a "functional" gene using ultrasonic microbubble destruction

1 reference

12 December 2020

DNA immunization using constant-current electroporation affords long-term protection from autochthonous mammary carcinomas in cancer-prone transgenic mice

1 reference

12 December 2020

Magnetofection: enhancing and targeting gene delivery by magnetic force in vitro and in vivo

1 reference

12 December 2020

Ultrasound-mediated gene delivery: kinetics of plasmid internalization and gene expression

1 reference

12 December 2020

The molecular basis of electroporation

1 reference

12 December 2020

Human apolipoprotein E expression from mouse skeletal muscle by electrotransfer of nonviral DNA (plasmid) and pseudotyped recombinant adeno-associated virus (AAV2/7).

1 reference

12 December 2020

Efficient nonviral cutaneous transfection

1 reference

12 December 2020

Intracellular barriers to non-viral gene transfer.

1 reference

12 December 2020

Use of the nuclease inhibitor aurintricarboxylic acid (ATA) for improved non-viral intratumoral in vivo gene transfer by jet-injection

1 reference

12 December 2020

Hydrodynamics-based gene delivery of naked DNA encoding fetal liver kinase-1 gene effectively suppresses the growth of pre-existing tumors

1 reference

12 December 2020

Inhibition of gene expression in mice muscle by in vivo electrically mediated siRNA delivery.

1 reference

12 December 2020

Nonviral in vivo gene delivery into tumors using a novel low volume jet-injection technology

1 reference

12 December 2020

Efficient and stable gene transfer following microinjection into nuclei of synchronized animal cells progressing from G1/S boundary to early S phase

1 reference

12 December 2020

In vivo gene transfer into muscle via electro-sonoporation

1 reference

12 December 2020

Evaluation of gas-filled microparticles and sonoporation as gene delivery system: feasibility study in rodent tumor models

1 reference

12 December 2020

Virus treatment questioned after gene therapy death

1 reference

12 December 2020

New strategies for nucleic acid delivery to conquer cellular and nuclear membranes

1 reference

12 December 2020

Engineering targeted viral vectors for gene therapy

1 reference

12 December 2020

Femtosecond laser treatment enhances DNA transfection efficiency in vivo

1 reference

12 December 2020

Enhancement of the efficiency of non-viral gene delivery by application of pulsed magnetic field

1 reference

12 December 2020

Gene transfer with echo-enhanced contrast agents: comparison between Albunex, Optison, and Levovist in mice--initial results

1 reference

12 December 2020

Intradermal DNA immunization by using jet-injectors in mice and monkeys

1 reference

12 December 2020

Femtosecond laser: a new intradermal DNA delivery method for efficient, long-term gene expression and genetic immunization

1 reference

12 December 2020

In vivo gene introduction into keratinocytes using jet injection

1 reference

12 December 2020

Effect of ultrasound-activated microbubbles on the cell electrophysiological properties.

1 reference

12 December 2020

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

1 reference

12 December 2020

In vitro and in vivo electric field-mediated permeabilization, gene transfer, and expression

1 reference

12 December 2020

Translational Diffusion of Macromolecule-sized Solutes in Cytoplasm and Nucleus

1 reference

12 December 2020

In vivo promoter activity and transgene expression in mammalian somatic tissues evaluated by using particle bombardment

1 reference

12 December 2020

Smooth muscle-specific gene delivery in the vasculature based on restriction of DNA nuclear import

1 reference

12 December 2020

Cell-specific nuclear import of plasmid DNA in smooth muscle requires tissue-specific transcription factors and DNA sequences

1 reference

12 December 2020

Nucleocytoplasmic transport of plasmid DNA: a perilous journey from the cytoplasm to the nucleus

1 reference

12 December 2020

Therapeutic ultrasound-mediated DNA to cell and nucleus: bioeffects revealed by confocal and atomic force microscopy

1 reference

12 December 2020

Gene therapy progress and prospects: electroporation and other physical methods.

1 reference

12 December 2020

Gene transfer by naked DNA into adult mouse brain.

1 reference

12 December 2020

Disposition and gene expression characteristics in solid tumors and skeletal muscle after direct injection of naked plasmid DNA in mice

1 reference

12 December 2020

Direct transfection of viral and plasmid DNA into the liver or spleen of mice

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12 December 2020

Ca2 -sensitive cytosolic nucleases prevent efficient delivery to the nucleus of injected plasmids.

1 reference

12 December 2020

Poly-L-glutamate, an anionic polymer, enhances transgene expression for plasmids delivered by intramuscular injection with in vivo electroporation

1 reference

12 December 2020

Electrogene therapy with p53 of murine sarcomas alone or combined with electrochemotherapy using cisplatin

1 reference

12 December 2020

Optimizing plasmid-based gene transfer for investigating skeletal muscle structure and function

1 reference

12 December 2020

Retroviral Vector Biosafety: Lessons from Sheep

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12 December 2020

Permeability changes induced by electric impulses in vesicular membranes

1 reference

12 December 2020

Intracellular trafficking of plasmids for gene therapy: mechanisms of cytoplasmic movement and nuclear import

1 reference

12 December 2020

Predominant cell-mediated immunity in the oral mucosa: gene gun-based vaccination against infectious diseases

1 reference

12 December 2020

Modeling electroporation in a single cell

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12 December 2020

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

1 reference

12 December 2020

Improvement of mouse beta-thalassemia by electrotransfer of erythropoietin cDNA.

1 reference

12 December 2020

Gene transfer of interleukin 10 to the murine cornea using electroporation

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12 December 2020

Size-dependent DNA mobility in cytoplasm and nucleus

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12 December 2020

Cell and animal imaging of electrically mediated gene transfer.

1 reference

12 December 2020

In vivo electrotransfer of the cardiotrophin-1 gene into skeletal muscle slows down progression of motor neuron degeneration in pmn mice

1 reference

12 December 2020

Gene Transfer into Mammalian Cells by Jet Injection

1 reference

12 December 2020

Highly efficient electro-gene therapy of solid tumor by using an expression plasmid for the herpes simplex virus thymidine kinase gene

1 reference

12 December 2020

Plasmid DNA entry into postmitotic nuclei of primary rat myotubes

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12 December 2020

Vectors and delivery systems in gene therapy.

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12 December 2020

Gene therapy death prompts review of adenovirus vector

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12 December 2020

Non-invasive opening of BBB by focused ultrasound.

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12 December 2020

Artificial cavitation nuclei significantly enhance acoustically induced cell transfection

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12 December 2020

Sonoporation by ultrasound-activated microbubble contrast agents: effect of acoustic exposure parameters on cell membrane permeability and cell viability.

1 reference

12 December 2020

Nonviral gene transfer to skeletal, smooth, and cardiac muscle in living animals

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12 December 2020

In vivo gene electroinjection and expression in rat liver

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12 December 2020

What is (still not) known of the mechanism by which electroporation mediates gene transfer and expression in cells and tissues

1 reference

12 December 2020

Intramuscular immunization with a monogenic plasmid DNA tuberculosis vaccine: Enhanced immunogenicity by electroporation and co-expression of GM-CSF transgene

1 reference

12 December 2020

DNA transfection of macaque and murine respiratory tissue is greatly enhanced by use of a nuclease inhibitor

1 reference

12 December 2020

Electric gene transfer to the liver following systemic administration of plasmid DNA.

1 reference

12 December 2020

Selective field effects on intracellular vacuoles and vesicle membranes with nanosecond electric pulses.

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12 December 2020

Gene transfer into mouse lyoma cells by electroporation in high electric fields

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12 December 2020

Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques

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12 December 2020

Pig liver gene therapy by noninvasive interventionist catheterism.

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12 December 2020

Electroporation-mediated transfer of plasmids to the lung results in reduced TLR9 signaling and inflammation

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12 December 2020

In vivo gene transfer into rabbit thyroid follicular cells by direct DNA injection

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12 December 2020

Complete in vivo reversal of the multidrug resistance phenotype by jet-injection of anti-MDR1 short hairpin RNA-encoding plasmid DNA.

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12 December 2020

Development of catheter-based procedures for transducing the isolated rabbit liver with plasmid DNA.

1 reference

12 December 2020

Generation and characterization of the humoral immune response to DNA immunization with a chimeric beta-amyloid-interleukin-4 minigene

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12 December 2020

In vivo electroporation enhances plasmid-based gene transfer of basic fibroblast growth factor for the treatment of ischemic limb

1 reference

12 December 2020

Non-viral VEGF(165) gene therapy--magnetofection of acoustically active magnetic lipospheres ('magnetobubbles') increases tissue survival in an oversized skin flap model

1 reference

12 December 2020

In situ gene transfer into animal tendons by injection of naked DNA and electrotransfer

1 reference

12 December 2020

Factors influencing the efficacy, longevity, and safety of electroporation-assisted plasmid-based gene transfer into mouse muscles

1 reference

12 December 2020

10.1007/S00232-010-9275-0

Identifiers

DOI

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22 August 2017

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