Genetic variants in MTNR1B affecting insulin secretion (Q37769561)

22 August 2017

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title

Genetic variants in MTNR1B affecting insulin secretion (English)

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22 August 2017

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4

Hans-Ulrich Häring

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22 August 2017

2

Harald Staiger

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22 August 2017

5

Andreas Fritsche

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22 August 2017

3

Fausto Machicao

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22 August 2017

1

Karsten Müssig

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22 August 2017

language of work or name

English

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publication date

1 September 2010

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22 August 2017

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22 August 2017

volume

42

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22 August 2017

issue

6

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22 August 2017

page(s)

387-393

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Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

22 August 2017

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DIETARY, EVOLUTIONARY, AND MODERNIZING INFLUENCES ON THE PREVALENCE OF TYPE 2 DIABETES

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A genome-wide association study identifies novel risk loci for type 2 diabetes

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Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

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Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

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A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

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A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

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A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

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Common variants in WFS1 confer risk of type 2 diabetes

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Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

21 January 2018

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Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.

21 January 2018

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Variants in MTNR1B influence fasting glucose levels

21 January 2018

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Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

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New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

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Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes

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Adverse metabolic and cardiovascular consequences of circadian misalignment

21 January 2018

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Polymorphisms within the novel type 2 diabetes risk locus MTNR1B determine beta-cell function

21 January 2018

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Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

21 January 2018

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A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

21 January 2018

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A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals

21 January 2018

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G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans

21 January 2018

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Common genetic variation in the melatonin receptor 1B gene (MTNR1B) is associated with decreased early-phase insulin response

21 January 2018

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Combined effects of single-nucleotide polymorphisms in GCK, GCKR, G6PC2 and MTNR1B on fasting plasma glucose and type 2 diabetes risk

21 January 2018

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Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians

21 January 2018

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Common genetic determinants of glucose homeostasis in healthy children: the European Youth Heart Study

21 January 2018

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Common variants at the GCK, GCKR, G6PC2-ABCB11 and MTNR1B loci are associated with fasting glucose in two Asian populations

21 January 2018

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MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans

21 January 2018

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Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B affect different aspects of pancreatic beta-cell function

21 January 2018

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Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men.

21 January 2018

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Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

21 January 2018

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Combined risk allele score of eight type 2 diabetes genes is associated with reduced first-phase glucose-stimulated insulin secretion during hyperglycemic clamps

21 January 2018

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Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor

21 January 2018

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Melatonin receptors are for the birds: Molecular analysis of two receptor subtypes differentially expressed in chick brain

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21 January 2018

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Receptor (MT(1)) mediated influence of melatonin on cAMP concentration and insulin secretion of rat insulinoma cells INS-1.

21 January 2018

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Identification and functional characterization of melatonin Mel 1a receptors in pancreatic beta cells: potential role in incretin-mediated cell function by sensitization of cAMP signaling

21 January 2018

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Function and expression of melatonin receptors on human pancreatic islets

21 January 2018

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Influence of melatonin and serotonin on glucose‐stimulated insulin release from perifused rat pancreatic islets in vitro

21 January 2018

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Melatonin inhibits insulin secretion and decreases PKA levels without interfering with glucose metabolism in rat pancreatic islets.

21 January 2018

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Insulin release from isolated mouse islets in vitro: No effect of physiological levels of melatonin or arginine vasotocin

21 January 2018

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Metabolic effects of melatonin on oxidative stress and diabetes mellitus

21 January 2018

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Effects of Pinealectomy and Pineal Incubation Medium and Sonicates on Insulin Release by Isolated Pancreatic Islets In Vitro

21 January 2018

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Loss of melatonin signalling and its impact on circadian rhythms in mouse organs regulating blood glucose

21 January 2018

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Melatonin and type 2 diabetes - a possible link?

21 January 2018

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Parallel signaling pathways of melatonin in the pancreatic beta-cell

21 January 2018

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Desensitization of G protein-coupled receptors and neuronal functions

21 January 2018

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Melatonin stimulates inositol-1,4,5-trisphosphate and Ca2 release from INS1 insulinoma cells

21 January 2018

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The expression of MT1 and MT2 melatonin receptor mRNA in several rat tissues

21 January 2018

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Decreased MT1 and MT2 melatonin receptor expression in extrapineal tissues of the rat during physiological aging

21 January 2018

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Functional expression of MT2 (Mel1b) melatonin receptors in human PAZ6 adipocytes

21 January 2018

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Melatonin stimulates glucose transport via insulin receptor substrate-1/phosphatidylinositol 3-kinase pathway in C2C12 murine skeletal muscle cells

21 January 2018

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In vivo activation of insulin receptor tyrosine kinase by melatonin in the rat hypothalamus.

21 January 2018

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Melatonin ameliorates high fat diet-induced diabetes and stimulates glycogen synthesis via a PKCzeta-Akt-GSK3beta pathway in hepatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/07853890.2010.502125

Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/07853890.2010.502125

Diabetic Goto Kakizaki rats as well as type 2 diabetic patients show a decreased diurnal serum melatonin level and an increased pancreatic melatonin-receptor status

21 January 2018

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https://api.crossref.org/works/10.3109/07853890.2010.502125

Agomelatine, a melatonin agonist with antidepressant properties

21 January 2018

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https://api.crossref.org/works/10.3109/07853890.2010.502125

Two variants on chromosome 17 confer prostate cancer risk and the one in TCF2 protects against type 2 diabetes

21 January 2018

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https://api.crossref.org/works/10.3109/07853890.2010.502125

SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/07853890.2010.502125

10.3109/07853890.2010.502125

21 January 2018

Identifiers

DOI

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22 August 2017

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