Autoimmunity and the pathogenesis of type 1 diabetes (Q37764866)

22 August 2017

1 reference

title

Autoimmunity and the pathogenesis of type 1 diabetes (English)

1 reference

22 August 2017

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Thomas R Csorba

1

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22 August 2017

Andrew W Lyon

series ordinal

2

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22 August 2017

Morley D Hollenberg

series ordinal

3

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22 August 2017

publication date

1 March 2010

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Critical Reviews in Clinical Laboratory Sciences

22 August 2017

published in

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22 August 2017

volume

47

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22 August 2017

issue

2

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22 August 2017

page(s)

51-71

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Immunology in diabetes: an update

22 August 2017

cites work

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Importance of persistent cellular and humoral immune changes before diabetes develops: prospective study of identical twins

21 January 2018

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Critical self-epitopes are key to the understanding of self-tolerance and autoimmunity

21 January 2018

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Characteristics of autoimmunity in type 1 diabetes and type 1.5 overlap with type 2 diabetes

21 January 2018

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Innate immunity and intestinal microbiota in the development of Type 1 diabetes

21 January 2018

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A role for innate immunity in type 1 diabetes?

21 January 2018

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Autoimmune destruction of pancreatic beta cells.

21 January 2018

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How can the innate immune system influence autoimmunity in type 1 diabetes and other autoimmune disorders?

21 January 2018

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Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients

21 January 2018

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The role of macrophages in T cell-mediated autoimmune diabetes in nonobese diabetic mice

21 January 2018

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Dendritic cells and the control of immunity

21 January 2018

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The interactions of dendritic cells with antigen-specific, regulatory T cells that suppress autoimmunity

21 January 2018

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Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue

21 January 2018

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Invasion of the killer B's in type 1 diabetes

21 January 2018

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Selecting and maintaining a diverse T-cell repertoire

21 January 2018

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Control of immune homeostasis by naturally arising regulatory CD4 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Regulatory T-cells in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

How do CD4 CD25 regulatory T cells control autoimmunity?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Functional waning of naturally occurring CD4 regulatory T-cells contributes to the onset of autoimmune diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

B-cell stimulatory factor 1 and not interleukin 2 is the autocrine growth factor for some helper T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Differential regulation of murine T lymphocyte subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Functional diversity of helper T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Type I diabetes mellitus in monozygotic twins: chronic progressive beta cell dysfunction.

21 January 2018

1 reference

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Structure and function of natural killer cell surface receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Variable receptors controlling activation and inhibition of NK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Natural killer cells and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

NK cells and type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Natural killer cells distinguish innocuous and destructive forms of pancreatic islet autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Altered natural killer cells in type 1 diabetic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Regulation of type 1 diabetes by NKT cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Identical twins discordant for type 1 diabetes show a different pattern of in vitro CD56 cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Multiple immuno-regulatory defects in type-1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Testing the NKT cell hypothesis of human IDDM pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Natural killer T cells: natural or unnatural regulators of autoimmunity?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Constitutive Cytokine mRNAs Mark Natural Killer (NK) and NK T Cells Poised for Rapid Effector Function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Role of cytokines in the pathogenesis of autoimmune diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Changes in autoreactive T cell avidity during type 1 diabetes development.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Genetic risk determines the emergence of diabetes-associated autoantibodies in young children

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Recognition of a subregion of human proinsulin by class I-restricted T cells in type 1 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Proinsulin-a pathogenic autoantigen in type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Insulin as a primary autoantigen for type 1A diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Insulin--a primary autoantigen in type 1 diabetes?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Binding of antibodies in sera from Type 1 (insulin-dependent) diabetic patients to glutamate decarboxylase from rat tissues. Evidence for antigenic and non-antigenic forms of the enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Demonstration of GAD-65 as the main immunogenic isoform of glutamate decarboxylase in type 1 diabetes and determination of autoantibodies using a radioligand produced by eukaryotic expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Autoreactive epitopes defined by diabetes-associated human monoclonal antibodies are localized in the middle and C-terminal domains of the smaller form of glutamate decarboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Antibodies to GAD and Tryptic Fragments of Islet 64K Antigen as Distinct Markers for Development of IDDM: Studies With Identical Twins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Antibodies to islet 37k antigen, but not to glutamate decarboxylase, discriminate rapid progression to IDDM in endocrine autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Relationship of the 37,000- and 40,000-M(r) tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

IA-2-autoantibodies complement GAD65-autoantibodies in new-onset IDDM patients and help predict impending diabetes in their siblings. The Belgian Diabetes Registry

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Regulatory T cells in the control of autoimmune diabetes: the case of the NOD mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

New reagents on the horizon for immune tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4 8 thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

A differential-avidity model for T-cell selection

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

During the early prediabetic period in NOD mice, the pathogenic CD8( ) T-cell population comprises multiple antigenic specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Central and peripheral autoantigen presentation in immune tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Genetic insights into disease mechanisms of autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

North-American twins with IDDM. Genetic, etiological, and clinical significance of disease concordance according to age, zygosity, and the interval after diagnosis in first twin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Type 1 diabetes: new perspectives on disease pathogenesis and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Immunopathogenesis and immunotherapeutic approaches to type 1A diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Molecular basis for HLA-DQ associations with IDDM.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

IDDM2-VNTR-encoded susceptibility to type 1 diabetes: dominant protection and parental transmission of alleles of the insulin gene-linked minisatellite locus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Variation in HLA-associated risks of childhood insulin-dependent diabetes in the Finnish population: I. Allele effects at A, B, and DR loci. DiMe Study Group. Childhood Diabetes in Finland

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Molecular aspects of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

HLA complex genes in type 1 diabetes and other autoimmune diseases. Which genes are involved?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

A correlation between the relative predisposition of MHC class II alleles to type 1 diabetes and the structure of their proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Genetic control of autoimmunity in Type I diabetes and associated disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Analysis of islet inflammation in human type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Differential beta-cell response to glucose, glucagon, and arginine during progression to type I (insulin-dependent) diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

First-phase insulin response in young healthy children at genetic and immunological risk for Type I diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Reduced CD4 T-cell-specific gene expression in human type 1 diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Concordance rates of insulin dependent diabetes mellitus: a population based study of young Danish twins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Small area variation in the incidence of childhood insulin-dependent diabetes mellitus in Yorkshire, UK: links with overcrowding and population density

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Age-dependent influences on the origins of autoimmune diabetes: evidence and implications

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

A review of the recent epidemiological data on the worldwide incidence of type 1 (insulin-dependent) diabetes mellitus. World Health Organization DIAMOND Project Group

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Epidemiology of IDDM in Switzerland. Increasing incidence rate and rural-urban differences in Swiss men born 1948-1972.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

The rise of childhood type 1 diabetes in the 20th century.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Identification of antigenic differences between the diabetogenic and non-diabetogenic variants of encephalomyocarditis virus using monoclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Amino acid differences in capsid protein, VP1, between diabetogenic and nondiabetogenic variants of encephalomyocarditis virus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Geographic differences in the risk of insulin-dependent diabetes mellitus: the importance of registries

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Migrant populations and the incidence of type 1 diabetes mellitus: an overview of the literature with a focus on the Spanish-heritage countries in Latin America

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Evidence for an environmental effect in the aetiology of insulin dependent diabetes in a transmigratory population

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Risk of childhood type 1 diabetes for Russians in Estonia and Siberia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Type 1 diabetes in Jewish Ethiopian immigrants in Israel: HLA class II immunogenetics and contribution of new environment

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Cow's milk and type 1 diabetes: the real debate is about mucosal immune function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Lack of association between early exposure to cow's milk protein and beta-cell autoimmunity. Diabetes Autoimmunity Study in the Young (DAISY)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Early Infant Feeding and Risk of Developing Type 1 Diabetes–Associated Autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Dietary toxins, endoplasmic reticulum (ER) stress and diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

21 January 2018

Toxic type 1 diabetes.

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

A missing link in the hygiene hypothesis?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Autoimmunity in congenital rubella syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Humoral beta-cell autoimmunity is rare in patients with the congenital rubella syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Interferon alpha--a potential link in the pathogenesis of viral-induced type 1 diabetes and autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Diabetes acceleration or prevention by a coxsackievirus B4 infection: critical requirements for both interleukin-4 and gamma interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Proinsulin: a unique autoantigen triggering autoimmune diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

T cells recognize multiple GAD65 and proinsulin epitopes in human type 1 diabetes, suggesting determinant spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

T-cell epitopes in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Post-translational protein modifications in antigen recognition and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

The insulin A-chain epitope recognized by human T cells is posttranslationally modified

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Higher molecular weight insulin precursors as autoantigens in type I diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Abnormal proinsulin congeners as autoantigens that initiate the pathogenesis of Type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

B cells are crucial for determinant spreading of T cell autoimmunity among beta cell antigens in diabetes-prone nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Proinsulin disulfide maturation and misfolding in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Proinsulin maturation, misfolding, and proteotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Risk assessment, prediction and prevention of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Insulin resistance is a risk factor for progression to type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Animal models of spontaneous autoimmune diabetes: notes on their relevance to the human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

A new marker in the HLA class I region is associated with the age at onset of IDDM

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Analysis of T-Cell Assays to Measure Autoimmune Responses in Subjects With Type 1 Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Genetics of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Progression of spontaneous autoimmune diabetes is associated with a switch in the killing mechanism used by autoreactive CTL

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

Progression of autoimmune diabetes driven by avidity maturation of a T-cell population

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10408361003787171

10.3109/10408361003787171

21 January 2018

Identifiers

DOI

1 reference

22 August 2017

1 reference