Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells (Q37736265)

22 August 2017

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title

Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells (English)

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22 August 2017

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Christopher K Glass

1

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22 August 2017

Kaoru Saijo

series ordinal

2

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22 August 2017

publication date

1 May 2010

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Nature Reviews Immunology

22 August 2017

published in

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22 August 2017

volume

10

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22 August 2017

issue

5

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22 August 2017

page(s)

365-376

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Nuclear receptors and lipid physiology: opening the X-files

22 August 2017

cites work

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Altered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-kappaB inhibition

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Control of inducible gene expression by signal-dependent transcriptional elongation

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A nuclear isoform of the focal adhesion LIM-domain protein Trip6 integrates activating and repressing signals at AP-1- and NF-kappaB-regulated promoters

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A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation

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A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma

31 March 2020

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A transcriptional co-repressor that interacts with nuclear hormone receptors

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Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

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Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways

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A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors

31 March 2020

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Estrogen down-regulation of the corepressor N-CoR: mechanism and implications for estrogen derepression of N-CoR-regulated genes

31 March 2020

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Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma

31 March 2020

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A nuclear receptor corepressor-dependent pathway mediates suppression of cytokine-induced C-reactive protein gene expression by liver X receptor

31 March 2020

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GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response

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The SMRT corepressor is regulated by a MEK-1 kinase pathway: inhibition of corepressor function is associated with SMRT phosphorylation and nuclear export

31 March 2020

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SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways

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MEKK1 plays a critical role in activating the transcription factor C/EBP-beta-dependent gene expression in response to IFN-gamma

31 March 2020

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SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron

31 March 2020

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Differential SUMOylation of LXRalpha and LXRbeta mediates transrepression of STAT1 inflammatory signaling in IFN-gamma-stimulated brain astrocytes

31 March 2020

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A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death

31 March 2020

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Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity

31 March 2020

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Glucocorticoids in T cell development and function*.

31 March 2020

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T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

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Pathophysiology of multiple sclerosis

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Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid

31 March 2020

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The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity

31 March 2020

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Orphan nuclear receptor NR4A2 expressed in T cells from multiple sclerosis mediates production of inflammatory cytokines

31 March 2020

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The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunity

31 March 2020

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Traditional concepts and future avenues of glucocorticoid action in experimental autoimmune encephalomyelitis and multiple sclerosis therapy

31 March 2020

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Peripheral T cells are the therapeutic targets of glucocorticoids in experimental autoimmune encephalomyelitis

31 March 2020

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Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR.

31 March 2020

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PPAR-delta senses and orchestrates clearance of apoptotic cells to promote tolerance

31 March 2020

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PPARgamma-dependent regulation of human macrophages in phagocytosis of apoptotic cells.

31 March 2020

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Biological roles and mechanistic actions of co-repressor complexes

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20414208

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The effect of a hormone of the adrenal cortex (17-hydroxy-11-dehydrocorticosterone; compound E) and of pituitary adrenocorticotropic hormone on rheumatoid arthritis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20414208

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414208

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRI2748

1 reference

22 August 2017

1 reference