A critical role for p27kip1 gene dosage in a mouse model of prostate carcinogenesis. (Q37705101)

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5 January 2020

title

A critical role for p27kip1 gene dosage in a mouse model of prostate carcinogenesis (English)

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10

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9

Robert D Cardiff

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author name string

Hui Gao

1

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Xuesong Ouyang

2

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Whitney Banach-Petrosky

3

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Alexander D Borowsky

4

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Yong Lin

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Minjung Kim

6

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Hansol Lee

7

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Weichung-Joseph Shih

8

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Cory Abate-Shen

11

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language of work or name

English

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publication date

29 November 2004

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Proceedings of the National Academy of Sciences of the United States of America

5 January 2020

published in

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volume

101

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issue

49

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page(s)

17204-17209

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Prostate pathology of genetically engineered mice: definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee.

5 January 2020

cites work

1 reference

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Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

23 August 2017

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Mouse strains for prostate tumorigenesis based on genes altered in human prostate cancer

23 August 2017

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Dosage of Fgf8 determines whether cell survival is positively or negatively regulated in the developing forebrain

23 August 2017

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Deregulated degradation of the cdk inhibitor p27 and malignant transformation.

23 August 2017

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Prostatic intraepithelial neoplasia in genetically engineered mice

23 August 2017

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Mouse models of prostate carcinogenesis.

23 August 2017

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ErbB2/Neu-induced, cyclin D1-dependent transformation is accelerated in p27-haploinsufficient mammary epithelial cells but impaired in p27-null cells

23 August 2017

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Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis.

23 August 2017

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Autochthonous mouse models for prostate cancer: past, present and future

23 August 2017

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Cyclin-dependent kinase inhibitor p27(Kip1) is required for mouse mammary gland morphogenesis and function

23 August 2017

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Molecular genetics of prostate cancer.

23 August 2017

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Role of p27 in prostate carcinogenesis

23 August 2017

1 reference

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CDK inhibitors: positive and negative regulators of G1-phase progression

23 August 2017

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D-type cyclins complex with the androgen receptor and inhibit its transcriptional transactivation ability

23 August 2017

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Roles for Nkx3.1 in prostate development and cancer

23 August 2017

1 reference

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Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

23 August 2017

1 reference

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Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1

23 August 2017

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The murine gene p27Kip1 is haplo-insufficient for tumour suppression

23 August 2017

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A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

23 August 2017

1 reference

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Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

23 August 2017

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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

23 August 2017

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p27Kip1 modulates cell migration through the regulation of RhoA activation.

23 August 2017

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The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

28 September 2017

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Nerve Growth Factor Induces Transcription of the p21 WAF1/CIP1 and Cyclin D1 Genes in PC12 Cells by Activating the Sp1 Transcription Factor

28 September 2017

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Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis.

28 September 2017

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Androgen-driven prostate epithelial cell proliferation and differentiation in vivo involve the regulation of p27.

23 June 2018

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Cdk inhibitor p27Kip1 and hormone dependence in breast cancer

23 June 2018

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Nkx3.1; Pten mutant mice develop invasive prostate adenocarcinoma and lymph node metastases

1 September 2018

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Overexpression of cyclin D1 is associated with metastatic prostate cancer to bone

1 September 2018

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PubMed

12 December 2020

Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse

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PubMed

12 December 2020

An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0407693101

1 reference

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5 January 2020

0 references

1 reference

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PubMed publication ID

15569926

1 reference