Pharmacometabolomics in Early-Phase Clinical Development. (Q37701143)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27127917 AND SRC:MED&resulttype=core&format=json

3 April 2020

1 reference

31 October 2020

Pharmacometabolomics in Early-Phase Clinical Development (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27127917 AND SRC:MED&resulttype=core&format=json

biomedical investigative technique

3 April 2020

main subject

1 reference

19 September 2019

1 reference

31 October 2020

1

1 reference

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3 April 2020

author name string

S Nandal

series ordinal

2

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3 April 2020

language of work or name

English

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publication date

29 April 2016

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Clinical and Translational Science

3 April 2020

1 June 2016

1 reference

31 October 2020

4 references

20 June 2019

19 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27127917 AND SRC:MED&resulttype=core&format=json

3 April 2020

31 October 2020

9

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3 April 2020

issue

3

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3 April 2020

page(s)

128-138

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Creative Commons Attribution-NonCommercial-NoDerivatives

3 April 2020

copyright license

3 references

20 June 2019

19 September 2019

31 October 2020

Pharmacometabolomics reveals that serotonin is implicated in aspirin response variability

1 reference

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Criteria for the use of omics-based predictors in clinical trials: explanation and elaboration

23 August 2017

1 reference

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Pharmacometabolomics: implications for clinical pharmacology and systems pharmacology.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Pharmacometabolomics of response to sertraline and to placebo in major depressive disorder - possible role for methoxyindole pathway

23 August 2017

1 reference

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Purine pathway implicated in mechanism of resistance to aspirin therapy: pharmacometabolomics-informed pharmacogenomics

23 August 2017

1 reference

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Pharmacogenomics in early-phase clinical development

23 August 2017

1 reference

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Pharmacometabolomics reveals racial differences in response to atenolol treatment

23 August 2017

1 reference

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Pharmacometabolomic mapping of early biochemical changes induced by sertraline and placebo

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Personal omics profiling reveals dynamic molecular and medical phenotypes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Pretreatment metabotype as a predictor of response to sertraline or placebo in depressed outpatients: a proof of concept.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Mining for therapeutic gold

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Glycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: pharmacometabolomics-informed pharmacogenomics

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Lipidomic analysis of variation in response to simvastatin in the Cholesterol and Pharmacogenetics Study.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Ongoing challenges in drug interaction safety: from exposure to pharmacogenomics

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

How to improve R&D productivity: the pharmaceutical industry's grand challenge

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Trends in risks associated with new drug development: success rates for investigational drugs

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Metabolomics applied to diabetes research: moving from information to knowledge

23 August 2017

1 reference

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Drugs, bugs, and personalized medicine: pharmacometabonomics enters the ring

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Metabolomics: a global biochemical approach to drug response and disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Metabolomics-based systems biology and personalized medicine: moving towards n = 1 clinical trials?

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Metabonomics techniques and applications to pharmaceutical research & development

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Pharmaco-metabonomic phenotyping and personalized drug treatment

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Metabolic footprinting and systems biology: the medium is the message

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Metabolomics – the link between genotypes and phenotypes

23 August 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

23 August 2017

https://api.crossref.org/works/10.1111/CTS.12396

'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Systematic functional analysis of the yeast genome

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Urinary organic acids quantitated by age groups in a healthy pediatric population

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Quantitative metabolic profiling based on gas chromatography

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Pharmacometabonomics and personalized medicine

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Parallel analysis of transcript and metabolic profiles: a new approach in systems biology

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Gas chromatographic mass spectrometric evaluation of free organic acids in human saliva

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Quantitative metabolic profiling of urinary organic acids by gas chromatography-mass spectrometry. Comparison of isolation methods

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Metabolomics in drug discovery and development.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Metabolomics: integration of a new "omics" with clinical pharmacology.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

A metabolic phenotyping approach to understanding relationships between metabolic syndrome and breast tumour responses to chemotherapy

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Pharmacometabonomic profiling as a predictor of toxicity in patients with inoperable colorectal cancer treated with capecitabine

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Predicting idiopathic toxicity of cisplatin by a pharmacometabonomic approach.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Use of pharmaco-metabonomics for early prediction of acetaminophen-induced hepatotoxicity in humans

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

An integrative approach for identifying a metabolic phenotype predictive of individualized pharmacokinetics of tacrolimus.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5351331

Susceptibility of Human Metabolic Phenotypes to Dietary Modulation

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111/CTS.12396

Metabonomics, dietary influences and cultural differences: a 1H NMR-based study of urine samples obtained from healthy British and Swedish subjects

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111/CTS.12396

Can the flow of medicines be improved? Fundamental pharmacokinetic and pharmacological principles toward improving Phase II survival

21 January 2018

1 reference

12 December 2020

Gas-liquid chromatographic study and estimation of several urinary aromatic acids

1 reference

12 December 2020

Mass spectrometry in lipid research

1 reference

12 December 2020

Metabolomic biomarkers: their role in the critical path

1 reference

12 December 2020

Identifiers

DOI

10.1111/CTS.12396

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27127917 AND SRC:MED&resulttype=core&format=json

3 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27127917 AND SRC:MED&resulttype=core&format=json

3 April 2020

PubMed publication ID

27127917

1 reference