Nerve growth factor as a paradigm of neurotrophins related to Alzheimer's disease. (Q37699041)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20186703 AND SRC:MED&resulttype=core&format=json

18 January 2020

review article

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title

Nerve growth factor as a paradigm of neurotrophins related to Alzheimer's disease (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20186703 AND SRC:MED&resulttype=core&format=json

18 January 2020

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2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20186703 AND SRC:MED&resulttype=core&format=json

18 January 2020

Giuseppina Amadoro

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20186703 AND SRC:MED&resulttype=core&format=json

18 January 2020

author name string

P Calissano

series ordinal

1

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18 January 2020

publication date

1 April 2010

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18 January 2020

number of pages

12

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Developmental Neurobiology

inferred from page(s)

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20186703 AND SRC:MED&resulttype=core&format=json

18 January 2020

volume

70

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20186703 AND SRC:MED&resulttype=core&format=json

18 January 2020

issue

5

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18 January 2020

page(s)

372-383

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A TrkA-to-p75NTR molecular switch activates amyloid beta-peptide generation during aging

18 January 2020

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Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation

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Endogenously produced neurotrophins regulate survival and differentiation of cortical progenitors via distinct signaling pathways.

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Monoclonal antibodies to nerve growth factor affect the postnatal development of the visual system

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Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease.

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Trk neurotrophin receptors in cholinergic neurons of patients with Alzheimer's disease

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Neurotrophins and activity-dependent development of the neocortex

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Gating of BDNF-induced synaptic potentiation by cAMP.

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Nerve growth factor favours long-term depression over long-term potentiation in layer II-III neurones of rat visual cortex.

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Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade

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TrkA pathway activation induced by amyloid-beta (Abeta).

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On the molecular basis linking Nerve Growth Factor (NGF) to Alzheimer's disease

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Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice.

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Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice

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Neurotrophins and their receptors: a convergence point for many signalling pathways

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Neurotrophin signalling in health and disease

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Down-regulation of trkA mRNA within nucleus basalis neurons in individuals with mild cognitive impairment and Alzheimer's disease

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Synaptic slaughter in Alzheimer's disease

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NGF is essential for hippocampal plasticity and learning

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7 January 2021

Reduced transport of [125I]nerve growth factor by cholinergic neurons and down-regulated TrkA expression in the medial septum of aged rats

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7 January 2021

Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion

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7 January 2021

Identification of a caspase-derived N-terminal tau fragment in cellular and animal Alzheimer's disease models.

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7 January 2021

Nerve growth factor and ras regulate beta-amyloid precursor protein gene expression in PC12 cells

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7 January 2021

The expression of p75 neurotrophin receptor protects against the neurotoxicity of soluble oligomers of beta-amyloid

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7 January 2021

Characterization of the signaling pathway downstream p75 neurotrophin receptor involved in beta-amyloid peptide-dependent cell death.

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7 January 2021

An aging pathway controls the TrkA to p75NTR receptor switch and amyloid beta-peptide generation

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7 January 2021

Does the p75 neurotrophin receptor mediate Abeta-induced toxicity in Alzheimer's disease?

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7 January 2021

Reduction of cortical TrkA but not p75(NTR) protein in early-stage Alzheimer's disease.

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7 January 2021

Detection of NGF-like activity in human brain tissue: increased levels in Alzheimer's disease

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7 January 2021

The failure in NGF maturation and its increased degradation as the probable cause for the vulnerability of cholinergic neurons in Alzheimer's disease

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7 January 2021

Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75.

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7 January 2021

Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice

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7 January 2021

Differential regulation of dynein and kinesin motor proteins by tau

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7 January 2021

Antibodies to nerve growth factor (NGF) prolong the sensitive period for monocular deprivation in the rat.

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7 January 2021

Nerve growth factor-induced neurite outgrowth in PC12 cells involves the coordinate induction of microtubule assembly and assembly-promoting factors

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7 January 2021

Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease

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7 January 2021

The coupling of a trkB tyrosine residue to LTP

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7 January 2021

The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease

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7 January 2021

Nerve growth factor mRNA and protein levels measured in the same tissue from normal and Alzheimer's disease parietal cortex

1 reference

7 January 2021

Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus

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7 January 2021

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

1 reference

7 January 2021

Regulation of promoter activity of the APP gene by cytokines and growth factors: implications in Alzheimer's disease

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7 January 2021

Down regulation of trk but not p75NTR gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer's disease

1 reference

7 January 2021

Nerve growth factor mRNA in peripheral and central rat tissues and in the human central nervous system: lesion effects in the rat brain and levels in Alzheimer's disease.

1 reference

7 January 2021

PACAP and NGF regulate common and distinct traits of the sympathoadrenal lineage: effects on electrical properties, gene markers and transcription factors in differentiating PC12 cells

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7 January 2021

Synaptic secretion of BDNF after high-frequency stimulation of glutamatergic synapses

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7 January 2021

Brain-derived neurotrophic factor, phosphorylated cyclic AMP response element binding protein and neuropeptide Y decline as early as middle age in the dentate gyrus and CA1 and CA3 subfields of the hippocampus.

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7 January 2021

Nerve growth factor and Alzheimer's disease

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7 January 2021

NGF content in the cerebral cortex of non-demented patients with amyloid-plaques and in symptomatic Alzheimer's disease.

1 reference

7 January 2021

Region-Specific Neurotrophin Imbalances in Alzheimer Disease

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7 January 2021

Decreased trkA neurotrophin receptor expression in the parietal cortex of patients with Alzheimer's disease

1 reference

7 January 2021

Long-distance retrograde neurotrophic signaling.

1 reference

7 January 2021

Increased p75(NTR) expression in hippocampal neurons containing hyperphosphorylated tau in Alzheimer patients

1 reference

7 January 2021

Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease

1 reference

7 January 2021

NGF mRNA is not decreased in frontal cortex from Alzheimer's disease patients.

1 reference

7 January 2021

Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus

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7 January 2021

Biological characterization and optical imaging of brain-derived neurotrophic factor-green fluorescent protein suggest an activity-dependent local release of brain-derived neurotrophic factor in neurites of cultured hippocampal neurons

1 reference

7 January 2021

Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation

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7 January 2021

Promoter activity of the gene encoding the beta-amyloid precursor protein is up-regulated by growth factors, phorbol ester, retinoic acid and interleukin-1.

1 reference

7 January 2021

Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin 1

1 reference

7 January 2021

Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice.

1 reference

7 January 2021

Induction of electrical excitability by NGF requires autocrine action of a CNTF-like factor

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7 January 2021

The nerve growth factor 35 years later

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7 January 2021

Differential effects of NGF and BDNF on voltage-gated calcium currents in embryonic basal forebrain neurons

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7 January 2021

Effects of neurotrophins on cortical plasticity: same or different?

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7 January 2021

Small molecule neurotrophin receptor ligands: novel strategies for targeting Alzheimer's disease mechanisms

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7 January 2021

The yin and yang of neurotrophin action

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7 January 2021

Nerve growth factor (NGF) prevents the shift in ocular dominance distribution of visual cortical neurons in monocularly deprived rats

1 reference

7 January 2021

Interaction of tau protein with the dynactin complex

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7 January 2021

Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses

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7 January 2021

NGF and BDNF signaling control amyloidogenic route and Abeta production in hippocampal neurons.

1 reference

7 January 2021

Activation of the amyloidogenic route by NGF deprivation induces apoptotic death in PC12 cells

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7 January 2021

Tyrosine kinase nerve growth factor receptor switches from prosurvival to proapoptotic activity via Abeta-mediated phosphorylation.

1 reference

7 January 2021

Nerve growth factor increases mRNA levels for the prion protein and the beta-amyloid protein precursor in developing hamster brain

1 reference

7 January 2021

Nerve growth factor in Alzheimerʼs disease: defective retrograde transport to nucleus basalis

1 reference

7 January 2021

Human cholinergic basal forebrain: chemoanatomy and neurologic dysfunction.

1 reference

7 January 2021

Reduction in p140-TrkA Receptor Protein within the Nucleus Basalis and Cortex in Alzheimer's Disease

1 reference

7 January 2021

Decreased trkA gene expression within basal forebrain neurons in Alzheimer's disease.

1 reference

7 January 2021

Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease

1 reference

7 January 2021

Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease

1 reference

7 January 2021

Regional specificity of alterations in NGF, BDNF and NT-3 levels in Alzheimer's disease.

1 reference

7 January 2021

Compartmental protein expression of Tau, GSK-3beta and TrkA in cholinergic neurons of aged rats.

1 reference

7 January 2021

Altered cellular distribution of phospho-tau proteins coincides with impaired retrograde axonal transport in neurons of aged rats.

1 reference

7 January 2021

Aberrant Tau Phosphorylation and Neurite Retraction during NGF Deprivation in PC12 Cells

1 reference

7 January 2021

Sortilin is essential for proNGF-induced neuronal cell death

1 reference

7 January 2021

Oxidative stress modulates tyrosine kinase receptor A and p75 receptor (low-affinity nerve growth factor receptor) expression in SHSY5Y neuroblastoma cells

1 reference

7 January 2021

Time window in cholinomimetic ability to rescue long-term potentiation in neurodegenerating anti-nerve growth factor mice

1 reference

7 January 2021

Acute cholinergic rescue of synaptic plasticity in the neurodegenerating cortex of anti-nerve-growth-factor mice.

1 reference

7 January 2021

Blocking the NGF-TrkA interaction rescues the developmental loss of LTP in the rat visual cortex: role of the cholinergic system.

1 reference

7 January 2021

TrkA activation in the rat visual cortex by antirat trkA IgG prevents the effect of monocular deprivation

1 reference

7 January 2021

Nerve growth factor-induced protein kinase C stimulation contributes to TrkA-dependent inhibition of p75 neurotrophin receptor sphingolipid signaling

1 reference

7 January 2021

Is Alzheimer's disease a synaptic disorder?

1 reference

7 January 2021

Neurotrophins as synaptic modulators

1 reference

7 January 2021

Ceramide stabilizes beta-site amyloid precursor protein-cleaving enzyme 1 and promotes amyloid beta-peptide biogenesis

1 reference

7 January 2021

Phenotypic knockout of nerve growth factor in adult transgenic mice reveals severe deficits in basal forebrain cholinergic neurons, cell death in the spleen, and skeletal muscle dystrophy.

1 reference

7 January 2021

Nerve growth factor increases the number of functional Na channels and induces TTX-resistant Na channels in PC12 pheochromocytoma cells.

1 reference

7 January 2021

Alzheimer's disease and NGF signaling

1 reference

7 January 2021

P75 neurotrophin receptor in the nucleus basalis of meynert in relation to age, sex, and Alzheimer's disease

1 reference

7 January 2021

Co-localization of high-affinity neurotrophin receptors in nucleus basalis of Meynert neurons and their differential reduction in Alzheimer's disease

1 reference

7 January 2021

Signalling organelle for retrograde axonal transport of internalized neurotrophins from the nerve terminal.

1 reference

7 January 2021

Alterations in trk A, trk B and trk C receptor immunoreactivities in parietal cortex and cerebellum in Alzheimer's disease

1 reference

7 January 2021

Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats.

1 reference

7 January 2021

Beta/A4-Amyloid increases nerve growth factor production in rat primary hippocampal astrocyte cultures

1 reference

7 January 2021

Neurotrophin regulation of synaptic transmission

1 reference

7 January 2021

Nerve growth factor in Alzheimer's disease: increased levels throughout the brain coupled with declines in nucleus basalis

1 reference

7 January 2021

Tau and HMW tau phosphorylation and compartmentalization in apoptotic neuronal PC12 cells

1 reference

7 January 2021

Failure of nicotine-dependent enhancement of synaptic efficacy at Schaffer-collateral CA1 synapses of AD11 anti-nerve growth factor transgenic mice.

1 reference

7 January 2021

Beta-amyloid(1-42) induces neuronal death through the p75 neurotrophin receptor.

1 reference

7 January 2021

Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress

1 reference

7 January 2021

Axonal transport and Alzheimer's disease

1 reference

7 January 2021

Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease

1 reference

7 January 2021

Low concentrations of aggregated beta-amyloid induce neurite formation via the neurotrophin receptor p75.

1 reference

7 January 2021

Nerve growth factor inhibits the expression of long-term potentiation in hippocampal slices.

1 reference

7 January 2021

Role of tau phosphorylation by glycogen synthase kinase-3beta in the regulation of organelle transport

1 reference

7 January 2021

Missorting of tau in neurons causes degeneration of synapses that can be rescued by the kinase MARK2/Par-1.

1 reference

7 January 2021

Neurotrophins and neuronal plasticity

1 reference

7 January 2021

A single pulse of nerve growth factor triggers long-term neuronal excitability through sodium channel gene induction

1 reference

7 January 2021

A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease

1 reference

7 January 2021

TrkA receptor activation by nerve growth factor induces shedding of the p75 neurotrophin receptor followed by endosomal gamma-secretase-mediated release of the p75 intracellular domain

1 reference

7 January 2021

Expression of neurotrophin and trk receptor genes in adult rats with fimbria transections: effect of intraventricular nerve growth factor and brain-derived neurotrophic factor administration

1 reference

7 January 2021

Nerve growth factor modulates the expression and secretion of beta-amyloid precursor protein through different mechanisms in PC12 cells

1 reference

7 January 2021

Nerve growth factor in treatment and pathogenesis of Alzheimer's disease.

1 reference

7 January 2021

A functional dynein-microtubule network is required for NGF signaling through the Rap1/MAPK pathway

1 reference

7 January 2021

Amyloid beta binds trimers as well as monomers of the 75-kDa neurotrophin receptor and activates receptor signaling

1 reference

7 January 2021

Small molecule, non-peptide p75 ligands inhibit Abeta-induced neurodegeneration and synaptic impairment

1 reference

7 January 2021

Association of Trk neurotrophin receptors with components of the cytoplasmic dynein motor

1 reference

7 January 2021