Antitumor activity of a novel anti-vascular endothelial growth factor receptor-1 monoclonal antibody that does not interfere with ligand binding (Q37687310)

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scientific article published on 19 September 2016

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English	Antitumor activity of a novel anti-vascular endothelial growth factor receptor-1 monoclonal antibody that does not interfere with ligand binding	scientific article published on 19 September 2016

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scholarly article

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Europe PubMed Central

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22 August 2017

Antitumor activity of a novel anti-vascular endothelial growth factor receptor-1 monoclonal antibody that does not interfere with ligand binding (English)

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Europe PubMed Central

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22 August 2017

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monoclonal antibody

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Grazia Graziani

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1 June 2020

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Pedro Miguel Lacal

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Cristina M Failla

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Cristina M Failla

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Maria Grazia Atzori

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Maria Grazia Atzori

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Manuel Scimeca

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Federica Ruffini

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Federica Ruffini

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1 June 2020

Annalisa S Dorio

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Annalisa S Dorio

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1 June 2020

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Elena Bonanno

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1 June 2020

Stefania D'Atri

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Stefania D'Atri

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1 June 2020

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Veronica Morea

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1 June 2020

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publication date

19 September 2016

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22 August 2017

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1 June 2020

7

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1 June 2020

45

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1 June 2020

72868-72885

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1 June 2020

Antagonist antibodies to vascular endothelial growth factor receptor 2 (VEGFR-2) as anti-angiogenic agents

1 reference

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23 August 2017

A VEGFR1 antagonistic peptide inhibits tumor growth and metastasis through VEGFR1-PI3K-AKT signaling pathway inhibition

1 reference

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23 August 2017

The peptidomimetic Vasotide targets two retinal VEGF receptors and reduces pathological angiogenesis in murine and nonhuman primate models of retinal disease

1 reference

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23 August 2017

VEGF pathway genetic variants as biomarkers of treatment outcome with bevacizumab: an analysis of data from the AViTA and AVOREN randomised trials

1 reference

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23 August 2017

Role of placenta growth factor in cancer and inflammation

1 reference

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Knockdown of VEGF receptor-1 (VEGFR-1) impairs macrophage infiltration, angiogenesis and growth of clear cell renal cell carcinoma (CRCC)

1 reference

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1 reference

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Chronic exposure of colorectal cancer cells to bevacizumab promotes compensatory pathways that mediate tumour cell migration

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23 August 2017

VEGFR-1 expressed by malignant melanoma-initiating cells is required for tumor growth

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Vascular endothelial growth factor receptor-1 in human cancer: concise review and rationale for development of IMC-18F1 (Human antibody targeting vascular endothelial growth factor receptor-1).

1 reference

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Structure-function analysis of VEGF receptor activation and the role of coreceptors in angiogenic signaling.

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Biological mechanisms of bevacizumab-associated adverse events

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VEGFs and receptors involved in angiogenesis versus lymphangiogenesis

1 reference

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FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?

1 reference

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23 August 2017

VEGF receptor protein-tyrosine kinases: structure and regulation

1 reference

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23 August 2017

Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels

1 reference

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23 August 2017

The crystal structure of placental growth factor in complex with domain 2 of vascular endothelial growth factor receptor-1

1 reference

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23 August 2017

Placental growth factor and its receptor, vascular endothelial growth factor receptor-1: novel targets for stimulation of ischemic tissue revascularization and inhibition of angiogenic and inflammatory disorders

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5341950

23 August 2017

Crystal Structure at 1.7 Å Resolution of VEGF in Complex with Domain 2 of the Flt-1 Receptor

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5341950

23 August 2017

Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor

1 reference

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Evolving molecularly targeted therapies for advanced-stage thyroid cancers

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6 September 2017

Placenta growth factor and neuropilin-1 collaborate in promoting melanoma aggressiveness.

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Placental growth factor in cancer

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Markers of response for the antiangiogenic agent bevacizumab

1 reference

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PlGF: a multitasking cytokine with disease-restricted activity

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VEGFR1 and PKCα signaling control melanoma vasculogenic mimicry in a VEGFR2 kinase-independent manner

1 reference

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14 September 2017

Expression of the soluble vascular endothelial growth factor receptor-1 in cutaneous melanoma: role in tumour progression.

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14 September 2017

Anti-vascular endothelial growth factor receptor-1 antagonist antibody as a therapeutic agent for cancer

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The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma

1 reference

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14 September 2017

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1 reference

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VEGFR-1 (FLT-1) activation modulates acute lymphoblastic leukemia localization and survival within the bone marrow, determining the onset of extramedullary disease.

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Vascular endothelial growth factor receptor-1 is deposited in the extracellular matrix by endothelial cells and is a ligand for the alpha 5 beta 1 integrin.

1 reference

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"Vasocrine" formation of tumor cell-lined vascular spaces: implications for rational design of antiangiogenic therapies

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1 September 2018

Levels of soluble vascular endothelial growth factor (VEGF) receptor 1 in astrocytic tumors and its relation to malignancy, vascularity, and VEGF-A.

1 reference

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Placental growth factor is a survival factor for tumor endothelial cells and macrophages

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Human melanoma cells secrete and respond to placenta growth factor and vascular endothelial growth factor.

1 reference

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The origin and function of tumor-associated macrophages

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR

1 reference

https://pubmed.ncbi.nlm.nih.gov/27655684

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Placenta growth factor induces melanoma resistance to temozolomide through a mechanism that involves the activation of the transcription factor NF-κB

1 reference

https://pubmed.ncbi.nlm.nih.gov/27655684

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.18632/ONCOTARGET.12108

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27655684 AND SRC:MED&resulttype=core&format=json

1 June 2020

PMC publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27655684 AND SRC:MED&resulttype=core&format=json

1 June 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27655684 AND SRC:MED&resulttype=core&format=json

1 June 2020

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