Associations between the C677T and A1298C polymorphisms of MTHFR and the efficacy and toxicity of methotrexate in rheumatoid arthritis: a meta-analysis (Q37672592)

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scientific article published on January 2010

Language	Label	Description	Also known as
English	Associations between the C677T and A1298C polymorphisms of MTHFR and the efficacy and toxicity of methotrexate in rheumatoid arthritis: a meta-analysis	scientific article published on January 2010

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

1 reference

Europe PubMed Central

Associations between the C677T and A1298C polymorphisms of MTHFR and the efficacy and toxicity of methotrexate in rheumatoid arthritis: a meta-analysis (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

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rheumatoid arthritis

1 reference

based on heuristic

inferred from title

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1 reference

based on heuristic

inferred from title

author name string

Young Ho Lee

1

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

Gwan Gyu Song

2

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 January 2010

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Europe PubMed Central

PubMed publication ID

21 August 2017

Clinical Drug Investigation

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Europe PubMed Central

PubMed publication ID

21 August 2017

30

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

101-108

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Europe PubMed Central

PubMed publication ID

21 August 2017

Meta-analysis: Principles and procedures

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https://api.crossref.org/works/10.2165/11531070-000000000-00000

21 January 2018

Bias in meta-analysis detected by a simple, graphical test

1 reference

https://api.crossref.org/works/10.2165/11531070-000000000-00000

21 January 2018

Quantifying heterogeneity in a meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate: mechanism of action, pharmacokinetics, clinical indications, and toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The rheumatoid arthritis patient in the clinic: comparing more than 1,300 consecutive DMARD courses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Are Thymidylate synthase and Methylene tetrahydrofolate reductase genes linked with methotrexate response (efficacy, toxicity) in Indian (Asian) rheumatoid arthritis patients?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Validation of the associations between single nucleotide polymorphisms or haplotypes and responses to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: a proposal for prospective pharmacogenomic study in clinical practice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The comparative efficacy and toxicity of second-line drugs in rheumatoid arthritis results of two metaanalyses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR)

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological and clinical implications of the MTHFR C677T polymorphism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between methotrexate efficacy & toxicity with C677T polymorphism of the methylenetetrahydrofolate gene in rheumatoid arthritis patients on folate supplementation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate related adverse effects in patients with rheumatoid arthritis are associated with the A1298C polymorphism of the MTHFR gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cost-effectiveness analysis of MTHFR polymorphism screening by polymerase chain reaction in Korean patients with rheumatoid arthritis receiving methotrexate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

677C>T and 1298A>C MTHFR polymorphisms affect methotrexate treatment outcome in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphisms in the thymidylate synthase and methylenetetrahydrofolate reductase genes and sensitivity to the low-dose methotrexate therapy in patients with rheumatoid arthritis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toward a better understanding of methotrexate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The C677T mutation in the methylenetetrahydrofolate reductase gene: a genetic risk factor for methotrexate-related elevation of liver enzymes in rheumatoid arthritis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development and validation of the European League Against Rheumatism response criteria for rheumatoid arthritis. Comparison with the preliminary American College of Rheumatology and the World Health Organization/International League Against Rheumati

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The frequent 5,10-methylenetetrahydrofolate reductase C677T polymorphism is associated with a common haplotype in whites, Japanese, and Africans

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: a forty-eight week, multicenter, randomized, double-blind, placebo-controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metaanalysis of methylenetetrahydrofolate reductase (MTHFR) polymorphisms affecting methotrexate toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Risk genotypes in folate-dependent enzymes and their association with methotrexate-related side effects in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20067328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/11531070-000000000-00000

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

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