Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload. (Q37662139)

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scientific article published on 19 September 2013

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English	Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload.	scientific article published on 19 September 2013

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22 February 2020

Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload (English)

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22 February 2020

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22 February 2020

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Kelsey H Fisher-Wellman

1

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22 February 2020

Laura A A Gilliam

2

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22 February 2020

Chien-Te Lin

3

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22 February 2020

Brook L Cathey

4

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22 February 2020

P Darrell Neufer

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22 February 2020

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19 September 2013

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22 February 2020

Free Radical Biology and Medicine

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22 February 2020

65

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22 February 2020

1201-1208

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22 February 2020

Rapid loss of adiponectin-stimulated fatty acid oxidation in skeletal muscle of rats fed a high fat diet is not due to altered muscle redox state

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High dietary fat selectively increases catalase expression within cardiac mitochondria

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Mitochondrial complex II can generate reactive oxygen species at high rates in both the forward and reverse reactions

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Protein thiyl radical mediates S-glutathionylation of complex I.

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1 reference

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1 reference

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S-glutathionylation uncouples eNOS and regulates its cellular and vascular function.

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Glutathione Synthesis Is Diminished in Patients With Uncontrolled Diabetes and Restored by Dietary Supplementation With Cysteine and Glycine

1 reference

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Hydrogen peroxide efflux from muscle mitochondria underestimates matrix superoxide production--a correction using glutathione depletion

1 reference

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The sites and topology of mitochondrial superoxide production

1 reference

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Subunit and catalytic component stoichiometries of an in vitro reconstituted human pyruvate dehydrogenase complex

1 reference

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23 August 2017

Reversible inhibition of alpha-ketoglutarate dehydrogenase by hydrogen peroxide: glutathionylation and protection of lipoic acid

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Dihydrolipoyl dehydrogenase as a source of reactive oxygen species inhibited by caloric restriction and involved in Saccharomyces cerevisiae aging.

1 reference

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2-Oxo acid dehydrogenase complexes in redox regulation

1 reference

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Topology of superoxide production from different sites in the mitochondrial electron transport chain

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Mapping the cysteine proteome: analysis of redox-sensing thiols

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6 September 2017

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14 September 2017

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25 June 2018

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

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1 reference

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1 reference

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1 reference

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1 reference

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12 December 2020

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10.1016/J.FREERADBIOMED.2013.09.008

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22 February 2020

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22 February 2020

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22 February 2020

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