Ligand-independent and tissue-selective androgen receptor inhibition by pyrvinium (Q37656304)

21 August 2017

Ligand-independent and tissue-selective androgen receptor inhibition by pyrvinium (English)

1 reference

21 August 2017

7

1 reference

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11 June 2020

Jeremy O Jones

8

1 reference

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11 June 2020

author name string

Minyoung Lim

1

1 reference

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11 June 2020

Maya Otto-Duessel

2

1 reference

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11 June 2020

Miaoling He

3

1 reference

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11 June 2020

Leila Su

4

1 reference

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11 June 2020

Dan Nguyen

5

1 reference

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11 June 2020

Emily Chin

6

1 reference

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11 June 2020

language of work or name

1 reference

3 January 2014

1 reference

21 August 2017

1 reference

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11 June 2020

volume

9

1 reference

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11 June 2020

issue

3

1 reference

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11 June 2020

page(s)

692-702

1 reference

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11 June 2020

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Androgen receptor splice variants mediate enzalutamide resistance in castration-resistant prostate cancer cell lines

6 September 2017

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Increased survival with enzalutamide in prostate cancer after chemotherapy

6 September 2017

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Androgen Receptor Splice Variants Activate Androgen Receptor Target Genes and Support Aberrant Prostate Cancer Cell Growth Independent of Canonical Androgen Receptor Nuclear Localization Signal

6 September 2017

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Novel irreversible small molecule inhibitors of replication protein A display single-agent activity and synergize with cisplatin

6 September 2017

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Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: induction of steroidogenesis and androgen receptor splice variants

6 September 2017

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Synthesis and biological evaluations of putative metabolically stable analogs of VN/124-1 (TOK-001): head to head anti-tumor efficacy evaluation of VN/124-1 (TOK-001) and abiraterone in LAPC-4 human prostate cancer xenograft model

6 September 2017

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Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α

6 September 2017

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Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant

6 September 2017

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Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor

6 September 2017

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Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy.

6 September 2017

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Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer

6 September 2017

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Castration-resistant prostate cancer: targeting androgen metabolic pathways in recurrent disease

6 September 2017

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Non-competitive androgen receptor inhibition in vitro and in vivo.

6 September 2017

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A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth

6 September 2017

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Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer

6 September 2017

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Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance

6 September 2017

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Proteomic methods for drug target discovery

6 September 2017

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Pathologic effects of testosterone deprivation

6 September 2017

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Target deconvolution strategies in drug discovery

6 September 2017

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A surface on the androgen receptor that allosterically regulates coactivator binding

6 September 2017

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Cell- and gene-specific regulation of primary target genes by the androgen receptor

6 September 2017

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Androgen receptor cross-talk with cell signalling pathways

6 September 2017

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Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

6 September 2017

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Structural basis of androgen receptor binding to selective androgen response elements.

6 September 2017

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Androgen receptor: a key molecule in the progression of prostate cancer to hormone independence

6 September 2017

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Molecular determinants of resistance to antiandrogen therapy

6 September 2017

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Beta-catenin binds to the activation function 2 region of the androgen receptor and modulates the effects of the N-terminal domain and TIF2 on ligand-dependent transcription

6 September 2017

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Glucocorticoid receptor homodimers and glucocorticoid-mineralocorticoid receptor heterodimers form in the cytoplasm through alternative dimerization interfaces

6 September 2017

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Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor

6 September 2017

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Distinct glucocorticoid receptor transcriptional regulatory surfaces mediate the cytotoxic and cytostatic effects of glucocorticoids

6 September 2017

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From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells

6 September 2017

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Androgen and glucocorticoid receptor heterodimer formation. A possible mechanism for mutual inhibition of transcriptional activity

6 September 2017

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Steroid receptor heterodimerization demonstrated in vitro and in vivo

6 September 2017

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Signal transduction and transcriptional regulation by glucocorticoid receptor-LexA fusion proteins

6 September 2017

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Intragenic Rearrangement and Altered RNA Splicing of the Androgen Receptor in a Cell-Based Model of Prostate Cancer Progression

6 September 2017

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Runx2 regulates survivin expression in prostate cancer cells

14 September 2017

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Interleukin-8 is a molecular determinant of androgen independence and progression in prostate cancer

14 September 2017

1 reference

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Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen.

14 September 2017

1 reference

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The androgen receptor: an overview.

28 September 2017

1 reference

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Target identification using drug affinity responsive target stability (DARTS)

28 September 2017

1 reference

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Effects of selective androgen receptor modulator (SARM) treatment in osteopenic female rats.

1 September 2018

1 reference

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Mechanisms of androgen receptor activation in advanced prostate cancer: differential co-activator recruitment and gene expression.

1 September 2018

1 reference

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HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability

1 September 2018

1 reference

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Changes in bone mineral density, lean body mass and fat content as measured by dual energy x-ray absorptiometry in patients with prostate cancer without apparent bone metastases given androgen deprivation therapy

1 September 2018

1 reference

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p300 mediates androgen-independent transactivation of the androgen receptor by interleukin 6

1 September 2018

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12 December 2020

The Androgen Receptor Gene Mutations Database

1 reference

12 December 2020

A cellular conformation-based screen for androgen receptor inhibitors

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12 December 2020

Discovery of orteronel (TAK-700), a naphthylmethylimidazole derivative, as a highly selective 17,20-lyase inhibitor with potential utility in the treatment of prostate cancer

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12 December 2020

Identifiers

DOI

10.1021/CB400759D

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24354286 AND SRC:MED&resulttype=core&format=json

11 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24354286 AND SRC:MED&resulttype=core&format=json

11 June 2020

PubMed publication ID

24354286

1 reference