Oxysterols in biological systems: the gastrointestinal tract, liver, vascular wall and central nervous system (Q37638753)

21 August 2017

1 reference

title

Oxysterols in biological systems: the gastrointestinal tract, liver, vascular wall and central nervous system (English)

1 reference

21 August 2017

Christophe Garenc

1

1 reference

21 August 2017

Pierre Julien

series ordinal

2

1 reference

21 August 2017

Emile Levy

series ordinal

3

1 reference

21 August 2017

publication date

1 January 2010

1 reference

21 August 2017

published in

Free Radical Research

1 reference

21 August 2017

volume

44

1 reference

21 August 2017

issue

1

1 reference

21 August 2017

page(s)

47-73

1 reference

Removal of cholesterol from extrahepatic sources by oxidative mechanisms

21 August 2017

cites work

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Rediscovery of cerebrosterol.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Transport of side-chain oxidized oxysterols in the human circulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Central nervous system: cholesterol turnover, brain development and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Rapid hepatic metabolism of 7-ketocholesterol by 11beta-hydroxysteroid dehydrogenase type 1: species-specific differences between the rat, human, and hamster enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Oxysterols in biological systems: sources, metabolism and pathophysiological relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Multifunctional roles of macrophages in the development and progression of atherosclerosis in humans and experimental animals

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Oxysterols: friends, foes, or just fellow passengers?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Effectors of rapid homeostatic responses of endoplasmic reticulum cholesterol and 3-hydroxy-3-methylglutaryl-CoA reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Are side-chain oxidized oxysterols regulators also in vivo?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Metabolism of 4 beta -hydroxycholesterol in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Comparison of the cytotoxic, pro-oxidant and pro-inflammatory characteristics of different oxysterols

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cytotoxic effects of oxysterols associated with human diseases: Induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Death-signaling pathways in human myeloid cells by oxLDL and its cytotoxic components 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Membrane and protein interactions of oxysterols

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Oxysterol signaling links cholesterol metabolism and inflammation via the liver X receptor in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Phospholipidosis and down-regulation of the PI3-K/PDK-1/Akt signalling pathway are vitamin E inhibitable events associated with 7-ketocholesterol-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Oxysterol mixtures, in atheroma-relevant proportions, display synergistic and proapoptotic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Oxidized LDL-induced injury and apoptosis in atherosclerosis. Potential roles for oxysterols

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Apoptosis in atherosclerosis: beneficial or detrimental?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Drug-induced phospholipidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Liver X receptors as integrators of metabolic and inflammatory signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Induction of 11beta-hydroxysteroid dehydrogenase type 1 but not -2 in human aortic smooth muscle cells by inflammatory stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

11 Beta-hydroxysteroid dehydrogenase type 1 is induced in human monocytes upon differentiation to macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Two 7 alpha-hydroxylase enzymes in bile acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

cDNA cloning of mouse and human cholesterol 25-hydroxylases, polytopic membrane proteins that synthesize a potent oxysterol regulator of lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Regulation of synthesis and degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase by low density lipoprotein and 25-hydroxycholesterol in UT-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Localization of sterol 27-hydroxylase immuno-reactivity in human atherosclerotic plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

A potential role for sterol 27-hydroxylase in atherogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Oxysterol biosynthetic enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Serum concentration of 27-hydroxycholesterol predicts the effects of high-cholesterol diet on plasma LDL cholesterol level.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Enhanced synthesis of the oxysterol 24(S),25-epoxycholesterol in macrophages by inhibitors of 2,3-oxidosqualene:lanosterol cyclase: a novel mechanism for the attenuation of foam cell formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Lipid Digestion and Absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Isolation and properties of the mixed lipid micelles present in intestinal content during fat digestion in man

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

21 January 2018

Watching Fat Digestion

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 2. Phase analysis and aggregation states of luminal lipids during duodenal fat digestion in healthy adult human beings

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Intestinal cholesterol transport proteins: an update and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

The role of orphan nuclear receptors in the regulation of cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Liver X receptor agonists as potential therapeutic agents for dyslipidemia and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Gene-selective modulation by a synthetic oxysterol ligand of the liver X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

A potent synthetic LXR agonist is more effective than cholesterol loading at inducing ABCA1 mRNA and stimulating cholesterol efflux

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

LXR-induced redistribution of ABCG1 to plasma membrane in macrophages enhances cholesterol mass efflux to HDL

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Intestinal ABCA1 directly contributes to HDL biogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Niemann-Pick C1 like 1 gene expression is down-regulated by LXR activators in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Modulation of intestinal cholesterol absorption by high glucose levels: impact on cholesterol transporters, regulatory enzymes, and transcription factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Oxidative stress influences cholesterol efflux in THP-1 macrophages: role of ATP-binding cassette A1 and nuclear factors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

The continuing importance of bile acids in liver and intestinal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Endocrine functions of bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

"Don't know much bile-ology"

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

The enzymes, regulation, and genetics of bile acid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Nuclear receptors in cholesterol catabolism: molecular biology of the enterohepatic circulation of bile salts and its role in cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Bile acids and lipoprotein metabolism: a renaissance for bile acids in the post-statin era?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Pharmacologic and surgical treatment of dyslipidemic children and adolescents

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Regulation of bile acid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Identification of oxysterols in human bile and pigment gallstones

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Oxysterols from human bile induce apoptosis of canine gallbladder epithelial cells in monolayer culture

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Intestinal bile acid transport: biology, physiology, and pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Molecular characterization and tissue distribution of a new organic anion transporter subtype (oatp3) that transports thyroid hormones and taurocholate and comparison with oatp2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

LXR alpha transactivates mouse organic solute transporter alpha and beta via IR-1 elements shared with FXR.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Effect of dietary cholesterol oxidation products on the plasma clearance of chylomicrons in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Discovering oxysterols in plasma: a window on the metabolome.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Human oxysterol-binding protein. I. Identification and characterization in liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol feeding increases plasma and aortic tissue cholesterol oxide levels in parallel: further evidence for the role of cholesterol oxidation in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Probucol reduces plasma and aortic wall oxysterol levels in cholesterol fed rabbits independently of its plasma cholesterol lowering effect

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Bile salt transporters: molecular characterization, function, and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

The functional expression of sodium-dependent bile acid transport in Madin-Darby canine kidney cells transfected with the cDNA for microsomal epoxide hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Enterohepatic bile salt transporters in normal physiology and liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Bile salt excretory pump: biology and pathobiology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Oxysterol 22(R)-hydroxycholesterol induces the expression of the bile salt export pump through nuclear receptor farsenoid X receptor but not liver X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Multiplexed flow cytometric analyses of pro- and anti-inflammatory cytokines in the culture media of oxysterol-treated human monocytic cells and in the sera of atherosclerotic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Increased plasma 7 beta-hydroxycholesterol concentrations in a population with a high risk for cardiovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Oxysterols: novel biologic roles for the 21st century

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cytotoxic cholesterol is generated by the hydrolysis of cytoplasmic cholesteryl ester and transported to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Selective distribution of oxysterols in atherosclerotic lesions and human plasma lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Morphological and biochemical aspects of apoptosis, oncosis and necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Acid sphingomyelinase in macrophage apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Generation of an oxidative stress precedes caspase activation during 7beta-hydroxycholesterol-induced apoptosis in U937 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Characterization and comparison of the mode of cell death, apoptosis versus necrosis, induced by 7beta-hydroxycholesterol and 7-ketocholesterol in the cells of the vascular wall

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Mechanisms of oxysterol-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Activation of caspase-3-dependent and -independent pathways during 7-ketocholesterol- and 7beta-hydroxycholesterol-induced cell death: a morphological and biochemical study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Impairment with various antioxidants of the loss of mitochondrial transmembrane potential and of the cytosolic release of cytochrome c occuring during 7-ketocholesterol-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Analysis of oxidative processes and of myelin figures formation before and after the loss of mitochondrial transmembrane potential during 7beta-hydroxycholesterol and 7-ketocholesterol-induced apoptosis: comparison with various pro-apoptotic chemica

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Ceramide generation occurring during 7beta-hydroxycholesterol- and 7-ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Effects of caspase inhibitors (z-VAD-fmk, z-VDVAD-fmk) on Nile Red fluorescence pattern in 7-ketocholesterol-treated cells: investigation by flow cytometry and spectral imaging microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

7-Ketocholesterol favors lipid accumulation and colocalizes with Nile Red positive cytoplasmic structures formed during 7-ketocholesterol-induced apoptosis: analysis by flow cytometry, FRET biphoton spectral imaging microscopy, and subcellular fract

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

7-Ketocholesterol predisposes human aorta smooth muscle cells to Fas-mediated death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

7-Ketocholesterol induces reversible cytochrome c release in smooth muscle cells in absence of mitochondrial swelling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

NAD(P)H oxidase Nox-4 mediates 7-ketocholesterol-induced endoplasmic reticulum stress and apoptosis in human aortic smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Comparative study of the cytotoxicity and apoptosis-inducing potential of commonly occurring oxysterols

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Qualitative and quantitative comparison of the cytotoxic and apoptotic potential of phytosterol oxidation products with their corresponding cholesterol oxidation products

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Apoptotic death of inflammatory cells in human atheroma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Foam cell death induced by 7beta-hydroxycholesterol is mediated by labile iron-driven oxidative injury: mechanisms underlying induction of ferritin in human atheroma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Increased ferritin gene expression in atherosclerotic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Ferritin in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Differential effects of mixtures of cholesterol oxidation products on bovine aortic endothelial cells and human monocytic U937 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Comparison of the apoptotic processes induced by the oxysterols 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol and 24S-hydroxycholesterol trafficking in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Oxysterols as markers of neurological disease--a review

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Oxysterols and neurodegenerative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

25-hydroxycholesterol provokes oligodendrocyte cell line apoptosis and stimulates the secreted phospholipase A2 type IIA via LXR beta and PXR.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Decreased levels of the brain specific 24S-hydroxycholesterol and cholesterol precursors in serum of multiple sclerosis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Changes in human plasma levels of the brain specific oxysterol 24S-hydroxycholesterol during progression of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Plasma 24S-hydroxycholesterol and other oxysterols in acute closed head injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cortical injury increases cholesterol 24S hydroxylase (Cyp46) levels in the rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol homeostasis: a role for oxysterols.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Sterols and isoprenoids: signaling molecules derived from the cholesterol biosynthetic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Control of apolipoprotein E secretion by 25-hydroxycholesterol and proinflammatory cytokines in the human astrocytoma cell line CCF-STTG1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Oxysterols and Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Outsourcing in the brain: do neurons depend on cholesterol delivery by astrocytes?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Primary human astrocytes produce 24(S),25-epoxycholesterol with implications for brain cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Endogenous 24(S),25-epoxycholesterol fine-tunes acute control of cellular cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Autoregulation of the human liver X receptor alpha promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

The effect of 24S-hydroxycholesterol on cholesterol homeostasis in neurons: quantitative changes to the cortical neuron proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol metabolism in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Importance of a novel oxidative mechanism for elimination of brain cholesterol. Turnover of cholesterol and 24(S)-hydroxycholesterol in rat brain as measured with 18O2 techniques in vivo and in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

From brain to bile. Evidence that conjugation and omega-hydroxylation are important for elimination of 24S-hydroxycholesterol (cerebrosterol) in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol metabolism in the brain: importance of 24S-hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

On the rate of translocation in vitro and kinetics in vivo of the major oxysterols in human circulation: critical importance of the position of the oxygen function.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol: from heart attacks to Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol in Alzheimer's disease and tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol and neuropathologic markers of AD: a population-based autopsy study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol and neuropathologic markers of AD: a population-based autopsy study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Systematic genetic study of Alzheimer disease in Latin America: mutation frequencies of the amyloid beta precursor protein and presenilin genes in Colombia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Apolipoprotein E4: an allele associated with many diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Dietary lipids in the aetiology of Alzheimer's disease: implications for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

ApoE-4 and age at onset of Alzheimer's disease: the NIMH genetics initiative

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Use of in vivo models to study the role of cholesterol in the etiology of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol, A beta and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Biochemical markers and risk factors of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol and cognition: rationale for the AD cholesterol-lowering treatment trial and sex-related Differences in beta-amyloid accumulation in the brains of spontaneously hypercholesterolemic Watanabe rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Alzheimer's disease--a dysfunction in cholesterol and lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Mild hypercholesterolemia is an early risk factor for the development of Alzheimer amyloid pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Is there a connection between the concentration of cholesterol circulating in plasma and the rate of neuritic plaque formation in Alzheimer disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol, lipid rafts, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol-dependent gamma-secretase activity in buoyant cholesterol-rich membrane microdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Plasma levels of 24S-hydroxycholesterol in patients with neurological diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Differential expression of cholesterol hydroxylases in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Regulation of alpha- and beta-secretase activity by oxysterols: cerebrosterol stimulates processing of APP via the alpha-secretase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Impact of 27-hydroxycholesterol on amyloid-beta peptide production and ATP-binding cassette transporter expression in primary human neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Hypercholesterolemia-induced Abeta accumulation in rabbit brain is associated with alteration in IGF-1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Activity-regulated cytoskeleton-associated protein in rodent brain is down-regulated by high fat diet in vivo and by 27-hydroxycholesterol in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Memory-influencing intra-basolateral amygdala drug infusions modulate expression of Arc protein in the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Recent advances in brain cholesterol dynamics: transport, domains, and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Plasma 24S-hydroxycholesterol: a peripheral indicator of neuronal degeneration and potential state marker for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Are the CSF levels of 24S-hydroxycholesterol a sensitive biomarker for mild cognitive impairment?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Proteolytic cascade in the amyloidogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol potentiates beta-amyloid-induced toxicity in human neuroblastoma cells: involvement of oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

The neurotoxic effect of 24-hydroxycholesterol on SH-SY5Y human neuroblastoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Abeta-mediated ROS production by Cu ions: structural insights, mechanisms and relevance to Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Comparative analysis of amyloid-beta chemical structure and amyloid plaque morphology of transgenic mouse and Alzheimer's disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Amyloid beta-protein interactions with membranes and cholesterol: causes or casualties of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol-dependent modulation of dendrite outgrowth and microtubule stability in cultured neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

The role of cholesterol in pathogenesis of Alzheimer's disease: dual metabolic interaction between amyloid beta-protein and cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Apolipoprotein E (ApoE) isoform-dependent lipid release from astrocytes prepared from human ApoE3 and ApoE4 knock-in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Apolipoprotein E and cholesterol metabolism in the pathogenesis and treatment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol homeostasis and function in neurons of the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Endothelial function and coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Statins and cardiovascular diseases: the multiple effects of lipid-lowering therapy by statins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Comparative tolerability of the HMG-CoA reductase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol and Alzheimer's disease: is there a link?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Statins and the risk of dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Use of statins in CNS disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Effects of statins on human cerebral cholesterol metabolism and secretion of Alzheimer amyloid peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Statin therapy for Alzheimer's disease: will it work?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Treatment with simvastatin in patients with Alzheimer's disease lowers both alpha- and beta-cleaved amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Central nervous system effects of HMG CoA reductase inhibitors: lovastatin and pravastatin on sleep and cognitive performance in patients with hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Reduction of plasma 24S-hydroxycholesterol (cerebrosterol) levels using high-dosage simvastatin in patients with hypercholesterolemia: evidence that simvastatin affects cholesterol metabolism in the human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Statins in the prevention and treatment of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Biochemical, physiological and medical aspects of ubiquinone function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Plasma 24S hydroxycholesterol response to statins in Alzheimer's disease patients: effects of gender, CYP46, and ApoE polymorphisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Re-assessing the relationship between cholesterol, statins and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Liver X receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the NPC1 mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Atorvastatin for the treatment of mild to moderate Alzheimer disease: preliminary results.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Effect of pravastatin on plasma sterols and oxysterols in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Hypertension and hypercholesterolaemia as risk factors for Alzheimer's disease: potential for pharmacological intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol modulation as an emerging strategy for the treatment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Biological activity of some oxygenated sterols

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

A role for the apoptosis inhibitory factor AIM/Spalpha/Api6 in atherosclerosis development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

LXR-dependent gene expression is important for macrophage survival and the innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Liver X receptor agonists suppress vascular smooth muscle cell proliferation and inhibit neointima formation in balloon-injured rat carotid arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: the importance of lesion stage and phagocytic efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Protein sensors for membrane sterols

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Orphan nuclear receptors as eLiXiRs and FiXeRs of sterol metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Nuclear receptors and lipid physiology: opening the X-files

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

FXR, a bile acid receptor and biological sensor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Sitosterolemia in ABC-transporter G5-deficient mice is aggravated on activation of the liver-X receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Abnormal metabolism of shellfish sterols in a patient with sitosterolemia and xanthomatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Genetic basis of sitosterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Dietary cholesterol absorption; more than just bile

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

ABCG5 and ABCG8 are expressed in gallbladder epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

ABCA1 mediates high-affinity uptake of 25-hydroxycholesterol by membrane vesicles and rapid efflux of oxysterol by intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDL

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

ATP-binding cassette transporter A1 (ABCA1) affects total body sterol metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

ABCA1 is essential for efficient basolateral cholesterol efflux during the absorption of dietary cholesterol in chickens

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

LXR/RXR ligand activation enhances basolateral efflux of beta-sitosterol in CaCo-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

ABCG5 and ABCG8 Are Obligate Heterodimers for Protein Trafficking and Biliary Cholesterol Excretion

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Treatment with controlled-release lovastatin decreases serum concentrations of human beta-amyloid (A beta) peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Asymmetrical regulation of scavenger receptor class B type I by apical and basolateral stimuli using Caco-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

Localization and role of NPC1L1 in cholesterol absorption in human intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/10715760903321804

10.3109/10715760903321804

21 January 2018

Identifiers

DOI

1 reference

21 August 2017

1 reference