The battlefield of perforin/granzyme cell death pathways. (Q37633282)

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12 February 2020

review article

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title

The battlefield of perforin/granzyme cell death pathways (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19915166 AND SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

1

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12 February 2020

Joseph A. Trapani

series ordinal

2

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12 February 2020

author name string

Ilia Voskoboinik

series ordinal

3

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12 February 2020

publication date

13 November 2009

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Journal of Leukocyte Biology

12 February 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19915166 AND SRC:MED&resulttype=core&format=json

12 February 2020

volume

87

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12 February 2020

issue

2

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12 February 2020

page(s)

237-243

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The orphan granzymes of humans and mice

12 February 2020

cites work

1 reference

Long-range disruption of gene expression by a selectable marker cassette

21 January 2018

1 reference

The granzyme B gene is highly polymorphic in wild mice but essentially invariant in common inbred laboratory strains.

21 January 2018

1 reference

Human and murine granzyme B exhibit divergent substrate preferences

21 January 2018

1 reference

The major human and mouse granzymes are structurally and functionally divergent

21 January 2018

1 reference

Perforin gene defects in familial hemophagocytic lymphohistiocytosis.

21 January 2018

1 reference

Temperature sensitivity of human perforin mutants unmasks subtotal loss of cytotoxicity, delayed FHL, and a predisposition to cancer

21 January 2018

1 reference

Residual active granzyme B in cathepsin C-null lymphocytes is sufficient for perforin-dependent target cell apoptosis

21 January 2018

1 reference

Papillon-Lefèvre syndrome: correlating the molecular, cellular, and clinical consequences of cathepsin C/dipeptidyl peptidase I deficiency in humans

21 January 2018

1 reference

21 January 2018

1 reference

Acquisition of murine NK cell cytotoxicity requires the translation of a pre-existing pool of granzyme B and perforin mRNAs.

21 January 2018

1 reference

Perforin, a pore-forming protein detectable by monoclonal antibodies, is a functional marker for killer cells

21 January 2018

1 reference

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

21 January 2018

1 reference

IL-15 mimics T cell receptor crosslinking in the induction of cellular proliferation, gene expression, and cytotoxicity in CD8 memory T cells

21 January 2018

1 reference

IL-21 induces the functional maturation of murine NK cells

21 January 2018

1 reference

Chromosome transfer activates and delineates a locus control region for perforin.

21 January 2018

1 reference

Constitutive expression of pore-forming protein in peripheral blood gamma/delta T cells: implication for their cytotoxic role in vivo

21 January 2018

1 reference

Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3).

21 January 2018

1 reference

21 January 2018

1 reference

Intrinsic and cooperative antigen-presenting functions of dendritic-cell subsets in vivo.

21 January 2018

1 reference

IL-2 regulates perforin and granzyme gene expression in CD8 T cells independently of its effects on survival and proliferation

21 January 2018

1 reference

Induction of cytotoxic granules in human memory CD8 T cell subsets requires cell cycle progression.

21 January 2018

1 reference

Induction of granzyme B and T cell cytotoxic capacity by IL-2 or IL-15 without antigens: multiclonal responses that are extremely lytic if triggered and short-lived after cytokine withdrawal

21 January 2018

1 reference

Interleukin 2 receptor signaling regulates the perforin gene through signal transducer and activator of transcription (Stat)5 activation of two enhancers

21 January 2018

1 reference

UVA induces granzyme B in human keratinocytes through MIF: implication in extracellular matrix remodeling.

21 January 2018

1 reference

Human keratinocytes acquire cellular cytotoxicity under UV-B irradiation. Implication of granzyme B and perforin

21 January 2018

1 reference

Granzyme K expressing cytotoxic T lymphocytes protects against influenza virus in granzyme AB-/- mice

21 January 2018

1 reference

Granzyme B-induced cell death exerted by ex vivo CTL: discriminating requirements for cell death and some of its signs

21 January 2018

1 reference

Cutting edge: rapid and efficient in vivo cytotoxicity by cytotoxic T cells is independent of granzymes A and B.

21 January 2018

1 reference

Measuring cell death mediated by cytotoxic lymphocytes or their granule effector molecules.

21 January 2018

1 reference

Perforin activity and immune homeostasis: the common A91V polymorphism in perforin results in both presynaptic and postsynaptic defects in function

21 January 2018

1 reference

Cytotoxic T lymphocyte-induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis

21 January 2018

1 reference

Single-cell perforin and granzyme expression reveals the anatomical localization of effector CD8 T cells in influenza virus-infected mice.

21 January 2018

1 reference

The genes for perforin, granzymes A-C and IFN-gamma are differentially expressed in single CD8( ) T cells during primary activation

21 January 2018

1 reference

Ultrastructural alteration of cytolytic T lymphocytes following their interaction with target cells. II. Morphogenesis of secretory granules and intracellular vacuoles

21 January 2018

1 reference

Ultrastructural alteration of cytolytic T lymphocytes following their interaction with target cells. I. Hypertrophy and change of orientation of the Golgi apparatus

21 January 2018

1 reference

Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes

21 January 2018

1 reference

Organelle proteomics: identification of the exocytic machinery associated with the natural killer cell secretory lysosome

21 January 2018

1 reference

A Proteomic Analysis of Lysosomal Integral Membrane Proteins Reveals the Diverse Composition of the Organelle

21 January 2018

1 reference

Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation

21 January 2018

1 reference

Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage

21 January 2018

1 reference

Delayed contraction of the CD8 T cell response toward lymphocytic choriomeningitis virus infection in mice lacking serglycin

21 January 2018

1 reference

Granzymes A and B are targeted to the lytic granules of lymphocytes by the mannose-6-phosphate receptor

21 January 2018

1 reference

The MACPF/CDC family of pore-forming toxins

21 January 2018

1 reference

Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense

21 January 2018

1 reference

A common fold mediates vertebrate defense and bacterial attack

21 January 2018

1 reference

Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit

21 January 2018

1 reference

The molecular basis for perforin oligomerization and transmembrane pore assembly

21 January 2018

1 reference

Calcium-dependent plasma membrane binding and cell lysis by perforin are mediated through its C2 domain: A critical role for aspartate residues 429, 435, 483, and 485 but not 491.

21 January 2018

1 reference

Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity

21 January 2018

1 reference

Granzyme B delivery via perforin is restricted by size, but not by heparan sulfate-dependent endocytosis

21 January 2018

1 reference

Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin

21 January 2018

1 reference

Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis

21 January 2018

1 reference

A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death

21 January 2018

1 reference

Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization.

21 January 2018

1 reference

Nuclear war: the granzyme A-bomb

21 January 2018

1 reference

Human and mouse granzyme A induce a proinflammatory cytokine response.

21 January 2018

1 reference

Extracellular activities of human granzymes. I. Granzyme A induces IL6 and IL8 production in fibroblast and epithelial cell lines

21 January 2018

1 reference

The inflammasomes: guardians of the body

21 January 2018

1 reference

Granzyme A is an interleukin 1 beta-converting enzyme

21 January 2018

1 reference

Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance

21 January 2018

1 reference

Defective regulatory and effector T cell functions in patients with FOXP3 mutations.

21 January 2018

1 reference

Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome

21 January 2018

1 reference

The lifestyle of naturally occurring CD4 CD25 Foxp3 regulatory T cells

21 January 2018

1 reference

Cutting edge: contact-mediated suppression by CD4 CD25 regulatory cells involves a granzyme B-dependent, perforin-independent mechanism

21 January 2018

1 reference

Activated CD4 CD25 T cells selectively kill B lymphocytes

21 January 2018

1 reference

Granzyme M mediates a novel form of perforin-dependent cell death

21 January 2018

1 reference

NK cell protease granzyme M targets alpha-tubulin and disorganizes the microtubule network

21 January 2018

1 reference

Functional analysis of granzyme M and its role in immunity to infection

21 January 2018

1 reference

Granzyme H destroys the function of critical adenoviral proteins required for viral DNA replication and granzyme B inhibition

21 January 2018

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Granzyme M is a regulatory protease that inactivates proteinase inhibitor 9, an endogenous inhibitor of granzyme B

21 January 2018

1 reference

Cleavage of La protein by granzyme H induces cytoplasmic translocation and interferes with La-mediated HCV-IRES translational activity

21 January 2018

1 reference

The role of granzyme B cluster proteases in cell-mediated cytotoxicity

21 January 2018

1 reference

Granzyme C supports efficient CTL-mediated killing late in primary alloimmune responses

21 January 2018

1 reference

Cell death induced by granzyme C.

21 January 2018

1 reference

Structure of granzyme C reveals an unusual mechanism of protease autoinhibition

21 January 2018

1 reference

Cell surface-bound heat shock protein 70 (Hsp70) mediates perforin-independent apoptosis by specific binding and uptake of granzyme B.

21 January 2018

1 reference

Extracellular matrix remodeling by human granzyme B via cleavage of vitronectin, fibronectin, and laminin.

21 January 2018

1 reference

Granzyme B induces smooth muscle cell apoptosis in the absence of perforin: involvement of extracellular matrix degradation

21 January 2018

1 reference

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

21 January 2018

1 reference

Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin.

21 January 2018

1 reference

Granzyme K: a novel mediator in acute airway inflammation

21 January 2018

1 reference

Altered levels and molecular forms of granzyme k in plasma from septic patients.

21 January 2018

1 reference