YAP enhances the pro-proliferative transcriptional activity of mutant p53 proteins (Q37623308)

21 August 2017

YAP enhances the pro-proliferative transcriptional activity of mutant p53 proteins (English)

1 reference

21 August 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26691213 AND SRC:MED&resulttype=core&format=json

9 June 2020

Giovanni Sorrentino

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26691213 AND SRC:MED&resulttype=core&format=json

9 June 2020

Fabio Valenti

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26691213 AND SRC:MED&resulttype=core&format=json

9 June 2020

Silvano Piazza

7

1 reference

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9 June 2020

Giannino Del Sal

9

1 reference

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9 June 2020

author name string

Eleonora Ingallina

3

1 reference

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9 June 2020

Maria Ferraiuolo

5

1 reference

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9 June 2020

Silvio Bicciato

6

1 reference

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9 June 2020

Sabrina Strano

8

1 reference

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9 June 2020

Giovanni Blandino

10

1 reference

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9 June 2020

publication date

21 December 2015

1 reference

21 August 2017

1 reference

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9 June 2020

volume

17

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9 June 2020

issue

2

1 reference

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9 June 2020

page(s)

188-201

1 reference

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describes a project that uses

9 June 2020

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/5290815

inferred from PubMed Central ID database lookup

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Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility

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ATM kinase enables the functional axis of YAP, PML and p53 to ameliorate loss of Werner protein-mediated oncogenic senescence.

23 August 2017

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The rebel angel: mutant p53 as the driving oncogene in breast cancer

23 August 2017

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23 August 2017

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23 August 2017

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The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

23 August 2017

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23 August 2017

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Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway

23 August 2017

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The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells

23 August 2017

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TopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73.

23 August 2017

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A Pin1/mutant p53 axis promotes aggressiveness in breast cancer

23 August 2017

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Role of YAP/TAZ in mechanotransduction

23 August 2017

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The role of mutant p53 in human cancer

23 August 2017

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The Hippo Signaling Pathway in Development and Cancer

23 August 2017

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The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

23 August 2017

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Modulation of the vitamin D3 response by cancer-associated mutant p53

23 August 2017

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Mutant p53-induced up-regulation of mitogen-activated protein kinase kinase 3 contributes to gain of function

23 August 2017

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Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells

23 August 2017

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Structural insights into the YAP and TEAD complex

23 August 2017

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Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content

23 August 2017

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When mutants gain new powers: news from the mutant p53 field.

23 August 2017

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A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer

23 August 2017

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A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

23 August 2017

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TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition

23 August 2017

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YAP: at the crossroad between transformation and tumor suppression

23 August 2017

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TEAD mediates YAP-dependent gene induction and growth control

23 August 2017

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TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4

23 August 2017

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Regulation of urokinase receptor expression by p53: novel role in stabilization of uPAR mRNA.

23 August 2017

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Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation

23 August 2017

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The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer

23 August 2017

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Oncogenic pathway signatures in human cancers as a guide to targeted therapies

23 August 2017

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An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

23 August 2017

1 reference

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The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage.

23 August 2017

1 reference

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The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

23 August 2017

1 reference

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Physical interaction with Yes-associated protein enhances p73 transcriptional activity

23 August 2017

1 reference

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A survey of 178 NF-Y binding CCAAT boxes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

Yes-associated protein (YAP65) is a proline-rich phosphoprotein that binds to the SH3 domain of the Yes proto-oncogene product

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

Mutant p53 reprograms TNF signaling in cancer cells through interaction with the tumor suppressor DAB2IP.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

Regulation of mitochondrial apoptosis by Pin1 in cancer and neurodegeneration

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

The cytoplasmic side of p53's oncosuppressive activities.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

6 September 2017

p53 mutations in cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

The YAP and TAZ transcription co-activators: Key downstream effectors of the mammalian Hippo pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

Mutant p53 oncogenic functions are sustained by Plk2 kinase through an autoregulatory feedback loop.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

Gain-of-function mutant p53 but not p53 deletion promotes head and neck cancer progression in response to oncogenic K-ras.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

Identification of a genetic signature of activated signal transducer and activator of transcription 3 in human tumors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

Mutant p53 cooperates with ETS and selectively up-regulates human MDR1 not MRP1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

TP53 mutation spectrum in breast cancer is subtype specific and has distinct prognostic relevance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

Metabolic control of YAP and TAZ by the mevalonate pathway.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

Disarming mutant p53 oncogenic function.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

The prognostic role of a gene signature from tumorigenic breast-cancer cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

NF-kappaB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

Stable suppression of tumorigenicity by virus-mediated RNA interference

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5290815

Molecular basis of the Li-Fraumeni syndrome: an update from the French LFS families

1 September 2018

1 reference

12 December 2020

Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy

1 reference

12 December 2020

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

12 December 2020

20 years studying p53 functions in genetically engineered mice

1 reference

12 December 2020

Identifiers

DOI

10.15252/EMBR.201540488

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26691213 AND SRC:MED&resulttype=core&format=json

release_ehn6vchmarclvawllvuwoga22u

9 June 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ehn6vchmarclvawllvuwoga22u

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26691213 AND SRC:MED&resulttype=core&format=json

9 June 2020

PubMed publication ID

26691213

1 reference