Mechanisms of obesity and related pathologies: androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction (Q37597592)

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scientific article published on 15 September 2009

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English	Mechanisms of obesity and related pathologies: androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction	scientific article published on 15 September 2009

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scholarly article

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Europe PubMed Central

PubMed publication ID

21 August 2017

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Europe PubMed Central

Mechanisms of obesity and related pathologies: androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction (English)

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Europe PubMed Central

PubMed publication ID

21 August 2017

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hypoandrogenism

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Abdulmaged M Traish

1

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Europe PubMed Central

PubMed publication ID

21 August 2017

Robert J Feeley

2

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Europe PubMed Central

PubMed publication ID

21 August 2017

Andre Guay

3

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Europe PubMed Central

PubMed publication ID

21 August 2017

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publication date

15 September 2009

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Europe PubMed Central

PubMed publication ID

21 August 2017

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Europe PubMed Central

PubMed publication ID

21 August 2017

276

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Europe PubMed Central

PubMed publication ID

21 August 2017

20

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

5755-5767

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Europe PubMed Central

PubMed publication ID

21 August 2017

Testosterone and erectile function: from basic research to a new clinical paradigm for managing men with androgen insufficiency and erectile dysfunction

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Association of hypertension, diabetes, dyslipidemia, and metabolic syndrome with obesity: findings from the National Health and Nutrition Examination Survey, 1999 to 2004.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

The dark side of testosterone deficiency: I. Metabolic syndrome and erectile dysfunction

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Epidemiologic trends in overweight and obesity

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Is dietary intake able to explain differences in body fatness in children and adolescents?

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Estimating the changes in energy flux that characterize the rise in obesity prevalence

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Beta-Adrenergic receptors, diet-induced thermogenesis, and obesity

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Is visceral obesity the cause of the metabolic syndrome?

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Abdominal obesity and the metabolic syndrome: contribution to global cardiometabolic risk

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Serum insulin and inflammatory markers in overweight individuals with and without dyslipidemia

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Identification and characterization of metabolically benign obesity in humans

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Effects of acute hyperinsulinemia on testosterone serum concentrations in adult obese and normal-weight men.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Association of endogenous testosterone with blood pressure and left ventricular mass in men. The Tromsø Study

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Waist circumference and testosterone levels in community dwelling men. The Tromsø study

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Epidemiology: testosterone and the metabolic syndrome

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Medical Consequences of Obesity

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Minireview: Adiposity, Inflammation, and Atherogenesis

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Fat as an endocrine organ: relationship to the metabolic syndrome.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

The link between abdominal obesity and the metabolic syndrome

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Visceral fat accumulation determines postprandial lipemic response, lipid peroxidation, DNA damage, and endothelial dysfunction in nonobese Korean men.

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

The link between abdominal obesity, metabolic syndrome and cardiovascular disease

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Adipokines: inflammation and the pleiotropic role of white adipose tissue

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

The metabolic syndrome

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

C-reactive protein levels and outcomes after statin therapy

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Inflammation, obesity, and the metabolic syndrome

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Endocrine functions of adipose tissue: focus on adiponectin

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Acquired obesity increases CD68 and tumor necrosis factor-alpha and decreases adiponectin gene expression in adipose tissue: a study in monozygotic twins.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Effects of Acquired Obesity on Endothelial Function in Monozygotic Twins*

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Associations of visceral adiposity and exercise participation with C-reactive protein, insulin resistance, and endothelial dysfunction in Korean healthy adults

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Visceral fat accumulation in men is positively associated with insulin, glucose, and C-peptide levels, but negatively with testosterone levels

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Effect of obesity and body fat distribution on sex hormones and insulin in men.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Sex hormones, inflammation and the metabolic syndrome: a population-based study

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

The metabolic syndrome and smoking in relation to hypogonadism in middle-aged men: a prospective cohort study

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Androgen deficiency, diabetes, and the metabolic syndrome in men.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Lifestyle and nutritional determinants of bioavailable androgens and related hormones in British men.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Body mass index in relation to semen quality and reproductive hormones among 1,558 Danish men.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Low serum testosterone and sex-hormone-binding-globulin in massively obese men.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Association of hypogonadism and type II diabetes in men attending an outpatient erectile dysfunction clinic

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Psychobiologic correlates of the metabolic syndrome and associated sexual dysfunction

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Is obesity correlated with sexual function in young men?

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Low levels of androgens in men with erectile dysfunction and obesity

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

The age related decrease in testosterone is significantly exacerbated in obese men with the metabolic syndrome. What are the implications for the relatively high incidence of erectile dysfunction observed in these men?

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Erectile dysfunction is associated with low bioactive testosterone levels and visceral adiposity in men with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Mild Hypogonadotropic hypogonadism in obese men.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Association of bioavailable, free, and total testosterone with insulin resistance: influence of sex hormone-binding globulin and body fat.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Reduced testosterone and adrenal C19 steroid levels in obese men.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Relation of steroid hormones to glucose tolerance and plasma insulin levels in men. Importance of visceral adipose tissue

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Hormonal control of regional fat distribution

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Low levels of sex hormone-binding globulin and testosterone predict the development of non-insulin-dependent diabetes mellitus in men. MRFIT Research Group. Multiple Risk Factor Intervention Trial

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Plasma free and non-sex-hormone-binding-globulin-bound testosterone are decreased in obese men in proportion to their degree of obesity

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Relative androgen deficiency in relation to obesity and metabolic status in older men.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Leptin and androgens in male obesity: evidence for leptin contribution to reduced androgen levels

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Obesity and male reproductive potential

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Obesity and endocrine disease

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

The Dark Side of Testosterone Deficiency: II. Type 2 Diabetes and Insulin Resistance

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

A 5-year follow-up study of disease incidence in men with an abnormal hormone pattern

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Erectile dysfunction and coronary risk factors: prospective results from the Massachusetts male aging study

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Central obesity is an independent predictor of erectile dysfunction in older men.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Sexual function and obesity.

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Obesity, low testosterone levels and erectile dysfunction

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Obesity and sexual dysfunction, male and female

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Phenotypic assessment of endothelial microparticles in diabetic and nondiabetic men with erectile dysfunction.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Obesity, the metabolic syndrome, and sexual dysfunction.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Is obesity an underlying factor in erectile dysfunction?

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Obesity and sexual dysfunction in younger Danish men.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Incidence of metabolic syndrome and insulin resistance in a population with organic erectile dysfunction

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Severity of erectile dysfunction in married impotent patients: interrelationship with anthropometry, hormones, metabolic profiles and lifestyle.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Are age, anthropometry and components of metabolic syndrome-risk factors interrelated with lower urinary tract symptoms in patients with erectile dysfunction? A prospective study.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Metabolic syndrome and incident end-stage peripheral vascular disease: a 14-year follow-up study in elderly Finns

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Effect of lifestyle changes on erectile dysfunction in obese men: a randomized controlled trial

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Is the metabolic syndrome an independent risk factor for erectile dysfunction?

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Prevalence of erectile dysfunction in patients with metabolic syndrome

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Low sex hormone-binding globulin, total testosterone, and symptomatic androgen deficiency are associated with development of the metabolic syndrome in nonobese men.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Androgen deficiency and abnormal penile duplex parameters in obese men with erectile dysfunction

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Sexual function in men older than 50 years of age: results from the health professionals follow-up study

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Altered Penile Vascular Reactivity and Erection in the Zucker Obese-Diabetic Rat

1 reference

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21 January 2018

Obesity, dyslipidemias and erectile dysfunction: a report of a subcommittee of the sexual medicine society of North America

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Correlates of low testosterone and symptomatic androgen deficiency in a population-based sample

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Hypothalamic-pituitary-testicular axis disruptions in older men are differentially linked to age and modifiable risk factors: the European Male Aging Study

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

The obesity epidemic and its cardiovascular consequences

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Improvements in sexual quality of life after moderate weight loss

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21 January 2018

Obesity and sexual quality of life.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Weight loss alone improves conduit and resistance artery endothelial function in young and older overweight/obese adults

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Concurrent improvement of the metabolic syndrome and lower urinary tract symptoms upon normalisation of plasma testosterone levels in hypogonadal elderly men.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Effects of testosterone gel followed by parenteral testosterone undecanoate on sexual dysfunction and on features of the metabolic syndrome

1 reference

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21 January 2018

A dose-response study of testosterone on sexual dysfunction and features of the metabolic syndrome using testosterone gel and parenteral testosterone undecanoate

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21 January 2018

Effects of testosterone replacement and its pharmacogenetics on physical performance and metabolism

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21 January 2018

Testosterone therapy in erectile dysfunction and hypogonadism

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Testosterone improves erectile function in hypogonadal patients with venous leakage.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

AA2500 testosterone gel normalizes androgen levels in aging males with improvements in body composition and sexual function

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21 January 2018

Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone mineral density in hypogonadal men.

1 reference

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21 January 2018

Exogenous testosterone (T) alone or with finasteride increases physical performance, grip strength, and lean body mass in older men with low serum T.

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21 January 2018

Effect of testosterone treatment on bone mineral density in men over 65 years of age.

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21 January 2018

Dihydrotestosterone decreases tumor necrosis factor-alpha and lipopolysaccharide-induced inflammatory response in human endothelial cells.

1 reference

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21 January 2018

The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men.

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21 January 2018

Testosterone replacement therapy improves insulin resistance, glycaemic control, visceral adiposity and hypercholesterolaemia in hypogonadal men with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Testosterone therapy prevents gain in visceral adipose tissue and loss of skeletal muscle in nonobese aging men.

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Testosterone therapy increases sexual desire in ageing men with low-normal testosterone levels and symptoms of androgen deficiency

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https://api.crossref.org/works/10.1111/J.1742-4658.2009.07305.X

21 January 2018

Effects of androgen therapy on adipose tissue and metabolism in older men.

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21 January 2018

Insulin resistance and endothelial dysfunction: the road map to cardiovascular diseases

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21 January 2018

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10.1111/J.1742-4658.2009.07305.X

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

ResearchGate publication ID

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