SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer (Q37595372)

21 August 2017

SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer (English)

1 reference

21 August 2017

1 reference

17

Elisa de Stanchina

0 references

Elizabeth J Adams

Elizabeth J Adams

12

0 references

Ping Mu

Ping Mu

1

0 references

Dong Gao

Dong Gao

9

0 references

Matteo Benelli

Matteo Benelli

3

0 references

Himisha Beltran

20

Himisha Beltran

1 reference

21 August 2017

23

Francesca Demichelis

1 reference

21 August 2017

15

Davide Prandi

1 reference

21 August 2017

4

Wouter R Karthaus

1 reference

21 August 2017

7

John Wongvipat

1 reference

21 August 2017

Zeda Zhang

2

1 reference

21 August 2017

Elizabeth Hoover

5

1 reference

21 August 2017

Chi-Chao Chen

6

1 reference

21 August 2017

Sheng-Yu Ku

8

1 reference

21 August 2017

Zhen Cao

10

1 reference

21 August 2017

Neel Shah

11

1 reference

21 August 2017

Wassim Abida

13

1 reference

21 August 2017

Philip A Watson

14

1 reference

21 August 2017

Chun-Hao Huang

16

1 reference

21 August 2017

Scott W Lowe

18

1 reference

21 August 2017

Leigh Ellis

19

1 reference

21 August 2017

Mark A Rubin

21

1 reference

21 August 2017

David W Goodrich

22

1 reference

21 August 2017

Charles L Sawyers

24

1 reference

21 August 2017

language of work or name

English

0 references

publication date

1 January 2017

1 reference

21 August 2017

5

1 reference

based on heuristic

inferred from page(s)

published in

Science

1 reference

21 August 2017

355

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21 August 2017

6320

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21 August 2017

84-88

1 reference

Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer

21 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

The Molecular Taxonomy of Primary Prostate Cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

SOX2 boosts major tumor progression genes in prostate cancer and is a functional biomarker of lymph node metastasis.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Integrative clinical genomics of advanced prostate cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Inhibition of pluripotency networks by the Rb tumor suppressor restricts reprogramming and tumorigenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

p53-dependent Nestin regulation links tumor suppression to cellular plasticity in liver cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Glucocorticoid receptor confers resistance to antiandrogens by bypassing androgen receptor blockade

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Overcoming mutation-based resistance to antiandrogens with rational drug design

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Sox2 is an androgen receptor-repressed gene that promotes castration-resistant prostate cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

miR-34 miRNAs provide a barrier for somatic cell reprogramming

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Suppression of induced pluripotent stem cell generation by the p53-p21 pathway

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

The Ink4/Arf locus is a barrier for iPS cell reprogramming

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Development of a second-generation antiandrogen for treatment of advanced prostate cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

A decade of transcription factor-mediated reprogramming to pluripotency

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Combined Tumor Suppressor Defects Characterize Clinically Defined Aggressive Variant Prostate Cancers

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Rb loss is characteristic of prostatic small cell neuroendocrine carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Tumor adaptation and resistance to RAF inhibitors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Very frequent p53 mutations in metastatic prostate carcinoma and in matched primary tumors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Rb regulates fate choice and lineage commitment in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5247742

Molecular determinants of resistance to antiandrogen therapy

14 September 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH4307

Androgen-regulated and highly tumorigenic human prostate cancer cell line established from a transplantable primary CWR22 tumor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH4307

Identification of an oncogenic RAB protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH4307

Identification of multipotent luminal progenitor cells in human prostate organoid cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH4307

STAR: ultrafast universal RNA-seq aligner

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH4307

RSEQtools: a modular framework to analyze RNA-Seq data using compact, anonymized data summaries

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH4307

Unraveling the clonal hierarchy of somatic genomic aberrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH4307

EXCAVATOR: detecting copy number variants from whole-exome sequencing data

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH4307

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH4307

Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28059768

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.AAH4307

1 reference

21 August 2017

0 references

1 reference

21 August 2017

PubMed publication ID

28059768

1 reference