Pharmacokinetics, pharmacodynamics and safety of recombinant canine FVIIa in a study dosing one haemophilia A and one haemostatically normal dog (Q37586365)

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scientific article published on 06 June 2011

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English	Pharmacokinetics, pharmacodynamics and safety of recombinant canine FVIIa in a study dosing one haemophilia A and one haemostatically normal dog	scientific article published on 06 June 2011

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scholarly article

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Europe PubMed Central

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21 August 2017

Pharmacokinetics, pharmacodynamics and safety of recombinant canine FVIIa in a study dosing one haemophilia A and one haemostatically normal dog (English)

1 reference

10.1111/J.1365-2516.2011.02536.X

https://api.crossref.org/works/10.1111/J.1365-2516.2011.02536.X

3 December 2024

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0 references

pharmacokinetics

1 reference

based on heuristic

inferred from title

pharmacodynamics

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based on heuristic

inferred from title

1

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T. Knudsen

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21645178

3 December 2024

Asger L. Jensen

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A. L. Jensen

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21645178

3 December 2024

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A. T. Kristensen

2

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Europe PubMed Central

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3 December 2024

T. C. Nichols

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21645178

3 December 2024

H. Agersø

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21645178

3 December 2024

M. Kjalke

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3 December 2024

M. Ezban

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21645178

3 December 2024

M. Tranholm

8

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3 December 2024

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21645178

3 December 2024

publication date

6 June 2011

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Europe PubMed Central

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21 August 2017

full work available at URL

https://europepmc.org/articles/pmc3925423?pdf=render

online access status

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21645178

3 December 2024

https://europepmc.org/articles/PMC3925423

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21645178

3 December 2024

https://europepmc.org/articles/PMC3925423?pdf=render

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21645178

3 December 2024

https://doi.org/10.1111/j.1365-2516.2011.02536.x

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21645178

3 December 2024

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111/j.1365-2516.2011.02536.x

1 reference

10.1111/J.1365-2516.2011.02536.X

https://api.crossref.org/works/10.1111/J.1365-2516.2011.02536.X

3 December 2024

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2516.2011.02536.x/fullpdf

1 reference

10.1111/J.1365-2516.2011.02536.X

https://api.crossref.org/works/10.1111/J.1365-2516.2011.02536.X

3 December 2024

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

17

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

962-970

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Canine specific ELISA for coagulation factor VII.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

23 August 2017

Intravascular inhibition of factor VIIa and the analogue NN1731 by antithrombin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

23 August 2017

Bio-distribution of pharmacologically administered recombinant factor VIIa (rFVIIa)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

23 August 2017

Recombinant canine B-domain-deleted FVIII exhibits high specific activity and is safe in the canine hemophilia A model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

23 August 2017

Protein replacement therapy and gene transfer in canine models of hemophilia A, hemophilia B, von willebrand disease, and factor VII deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

23 August 2017

Successful treatment of canine hemophilia by continuous expression of canine FVIIa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

23 August 2017

Long-term expression of murine activated factor VII is safe, but elevated levels cause premature mortality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

23 August 2017

Canine hemophilia; observations on the course, the clotting anomaly, and the effect of blood transfusions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

23 August 2017

What does it take to make the perfect clot?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

23 August 2017

Efficacy and safety of recombinant factor VIIa for treatment of severe bleeding: a systematic review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

23 August 2017

Recombinant factor VIIa: review of efficacy, dosing regimens and safety in patients with congenital and acquired factor VIII or IX inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

23 August 2017

Safety profile of recombinant factor VIIa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

23 August 2017

Pharmacokinetics of recombinant activated factor VII (rFVIIa).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

23 August 2017

The tissue factor pathway: how it has become a "prima ballerina"

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

23 August 2017

Use of human factor VIIa in the treatment of two hemophilia A patients with high-titer inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

23 August 2017

Effect of recombinant factor VIIa on the hemostatic defect in dogs with hemophilia A, hemophilia B, and von Willebrand disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

23 August 2017

A novel missense mutation responsible for factor VII deficiency in research Beagle colonies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

14 September 2017

Novel therapeutic approach for hemophilia using gene delivery of an engineered secreted activated Factor VII.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

28 September 2017

Plasma profiles of IL-6 and TNF with fever-inducing doses of lipopolysaccharide in dogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

28 September 2017

Mechanism of antithrombin III inhibition of factor VIIa/tissue factor activity on cell surfaces. Comparison with tissue factor pathway inhibitor/factor Xa-induced inhibition of factor VIIa/tissue factor activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

28 September 2017

Comparison of kaolin and tissue factor activated thromboelastography in haemophilia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

25 June 2018

Platelet activity of high-dose factor VIIa is independent of tissue factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

25 June 2018

Characterization of canine coagulation factor VII and its complex formation with tissue factor: canine-human cross-species compatibility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

1 September 2018

Evaluation of thromboelastography for monitoring recombinant activated factor VII ex vivo in haemophilia A and B patients with inhibitors: a multicentre trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

1 September 2018

Randomized, prospective clinical trial of recombinant factor VIIa for secondary prophylaxis in hemophilia patients with inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

1 September 2018

Preferential localization of recombinant factor VIIa to platelets activated with a combination of thrombin and a glycoprotein VI receptor agonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

1 September 2018

Pharmacokinetics of activated recombinant coagulation factor VII (NovoSeven) in children vs. adults with haemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

1 September 2018

Pharmacokinetic evaluation of recombinant, activated factor VII in patients with inherited factor VII deficiency.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

1 September 2018

Complex-dependent inhibition of factor VIIa by antithrombin III and heparin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

1 September 2018

Safety and initial clinical efficacy of three dose levels of recombinant activated factor VII (rFVIIa): results of a phase I study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

1 September 2018

Pharmacokinetics and pharmacodynamics of recombinant factor VIIa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925423

1 September 2018

Factor VII survival and turnover in dogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645178

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombelastography

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645178

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of activated factor VII levels in plasma using a tissue factor mutant selectively deficient in promoting factor VII activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645178

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-reactivity of human molecular markers for detection of prethrombotic states in various animal species

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645178

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A study of the pharmacokinetics and safety of recombinant activated factor VII in healthy Caucasian and Japanese subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645178

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome of clinical islet transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645178

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue factor activated thromboelastography correlates to clinical signs of bleeding in dogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645178

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma elimination kinetics for factor VII are independent of its activation to factor VIIa and complex formation with plasma inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645178

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of reference intervals for kaolin-activated thromboelastography in dogs including an assessment of the effects of sex and anticoagulant use

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645178

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of recombinant activated factor VII on perioperative blood loss in patients undergoing retropubic prostatectomy: a double-blind placebo-controlled randomised trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/21645178

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Tissue Factor Pathway: How It Has Become a “Prima Ballerina”

2

1 reference

10.1111/J.1365-2516.2011.02536.X

https://api.crossref.org/works/10.1111/J.1365-2516.2011.02536.X

3 December 2024

Identifiers

10.1111/J.1365-2516.2011.02536.X

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

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