AMPK activation of muscle autophagy prevents fasting-induced hypoglycemia and myopathy during aging (Q37583673)

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16 February 2020

title

AMPK activation of muscle autophagy prevents fasting-induced hypoglycemia and myopathy during aging (English)

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16 February 2020

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2

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16 February 2020

Alex E Green

7

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16 February 2020

Bruce Ernest Kemp

8

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16 February 2020

author name string

Adam L Bujak

1

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16 February 2020

James S Lally

3

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16 February 2020

Rebecca J Ford

4

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16 February 2020

Sally J Kang

5

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16 February 2020

Irena A Rebalka

6

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16 February 2020

Thomas J Hawke

9

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16 February 2020

Jonathan D Schertzer

10

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16 February 2020

Gregory R Steinberg

11

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16 February 2020

publication date

1 June 2015

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full work available at URL

16 February 2020

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233441

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published in

Cell Metabolism

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16 February 2020

volume

21

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16 February 2020

issue

6

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16 February 2020

page(s)

883-890

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Autophagy impairment in muscle induces neuromuscular junction degeneration and precocious aging.

16 February 2020

cites work

1 reference

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Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin.

23 August 2017

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Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease

23 August 2017

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Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathy

23 August 2017

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Skeletal muscle aging and the mitochondrion

23 August 2017

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Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy

23 August 2017

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Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice

23 August 2017

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AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise.

23 August 2017

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Mitochondrial DNA mutations in disease and aging

23 August 2017

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Liver autophagy contributes to the maintenance of blood glucose and amino acid levels

23 August 2017

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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

23 August 2017

1 reference

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Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

23 August 2017

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Autophagy in skeletal muscle

23 August 2017

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Mitochondrial turnover and aging of long-lived postmitotic cells: the mitochondrial-lysosomal axis theory of aging

23 August 2017

1 reference

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AMPK phosphorylation of raptor mediates a metabolic checkpoint

23 August 2017

1 reference

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FoxO3 controls autophagy in skeletal muscle in vivo

23 August 2017

1 reference

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The AMP-activated protein kinase: role in regulation of skeletal muscle metabolism and insulin sensitivity

23 August 2017

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Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis

23 August 2017

1 reference

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In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker

23 August 2017

1 reference

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TSC2 mediates cellular energy response to control cell growth and survival

23 August 2017

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The syndrome of cardiac cachexia

23 August 2017

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

23 August 2017

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Autophagy in skeletal muscle homeostasis and in muscular dystrophies

23 August 2017

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Skeletal muscle, autophagy, and physical activity: the ménage à trois of metabolic regulation in health and disease.

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AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network

6 September 2017

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AMPK promotes skeletal muscle autophagy through activation of forkhead FoxO3a and interaction with Ulk1.

6 September 2017

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6 September 2017

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Mitochondrial fission and remodelling contributes to muscle atrophy.

14 September 2017

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AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice.

14 September 2017

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1 September 2018

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1 September 2018

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12 December 2020

PGC1-α over-expression prevents metabolic alterations and soleus muscle atrophy in hindlimb unloaded mice

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12 December 2020

Autophagic response to exercise training in skeletal muscle with age

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12 December 2020

Alanine: Key Role in Gluconeogenesis

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12 December 2020

AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity

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12 December 2020

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26039451 AND SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26039451 AND SRC:MED&resulttype=core&format=json

16 February 2020

PubMed publication ID

26039451

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26039451 AND SRC:MED&resulttype=core&format=json