Human copper transporter 1 lacking O-linked glycosylation is proteolytically cleaved in a Rab9-positive endosomal compartment. (Q37459937)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19684018 AND SRC:MED&resulttype=core&format=json

5 February 2020

title

Human copper transporter 1 lacking O-linked glycosylation is proteolytically cleaved in a Rab9-positive endosomal compartment (English)

1 reference

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5 February 2020

1 reference

1 reference

0 references

4

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5 February 2020

author name string

Edward B Maryon

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19684018 AND SRC:MED&resulttype=core&format=json

5 February 2020

Jing Zhang

series ordinal

2

1 reference

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5 February 2020

John W Jellison

series ordinal

3

1 reference

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5 February 2020

language of work or name

English

0 references

publication date

14 August 2009

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19684018 AND SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

5 February 2020

published in

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5 February 2020

volume

284

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5 February 2020

issue

41

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5 February 2020

page(s)

28104-28114

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Three-dimensional structure of the human copper transporter hCTR1.

5 February 2020

cites work

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Projection structure of the human copper transporter CTR1 at 6-A resolution reveals a compact trimer with a novel channel-like architecture

23 August 2017

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23 August 2017

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Rab9 GTPase regulates late endosome size and requires effector interaction for its stability

23 August 2017

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23 August 2017

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Copper-stimulated endocytosis and degradation of the human copper transporter, hCtr1

23 August 2017

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Molecular characterization of hCTR1, the human copper uptake protein

23 August 2017

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Biochemical and genetic analyses of yeast and human high affinity copper transporters suggest a conserved mechanism for copper uptake

23 August 2017

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Rab GTPases, intracellular traffic and disease.

23 August 2017

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Biochemical characterization of the human copper transporter Ctr1

23 August 2017

1 reference

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Function, structure, and mechanism of intracellular copper trafficking proteins

23 August 2017

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Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development

23 August 2017

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Furin-mediated processing in the early secretory pathway: sequential cleavage and degradation of misfolded insulin receptors

23 August 2017

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23 August 2017

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Concepts and principles of O-linked glycosylation

23 August 2017

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23 August 2017

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hCTR1: a human gene for copper uptake identified by complementation in yeast

23 August 2017

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23 August 2017

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

23 August 2017

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Elimination of the O-linked glycosylation site at Thr 104 results in the generation of a soluble human-transferrin receptor.

23 August 2017

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23 August 2017

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O-linked glycosylation at threonine 27 protects the copper transporter hCTR1 from proteolytic cleavage in mammalian cells

28 September 2017

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2 September 2018

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Leupeptin, a calpain inhibitor, protects inner ear hair cells from aminoglycoside ototoxicity

2 September 2018

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Activation of MEK/ERK and PI3K/Akt pathways by fibronectin requires integrin alphav-mediated ADAM activity in hepatocellular carcinoma: a novel functional target for gefitinib

2 September 2018

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The mechanism of copper uptake mediated by human CTR1: a mutational analysis.

2 September 2018

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Eukaryotic CTR copper uptake transporters require two faces of the third transmembrane domain for helix packing, oligomerization, and function.

2 September 2018

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Prediction of proteasome cleavage motifs by neural networks

2 September 2018

1 reference

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Maturation of the trans-Golgi network protease furin: compartmentalization of propeptide removal, substrate cleavage, and COOH-terminal truncation

2 September 2018

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Stage-specific inhibition of Xenopus embryogenesis by aprotinin, a serine protease inhibitor

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19684018

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Accelerated amyloid deposition in mice treated with the aspartic protease inhibitor, pepstatin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19684018

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibition versus induction of apoptosis by proteasome inhibitors depends on concentration

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19684018

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.044925

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19684018 AND SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19684018 AND SRC:MED&resulttype=core&format=json

5 February 2020

PubMed publication ID

19684018

1 reference