ROCK mediates phorbol ester-induced apoptosis in prostate cancer cells via p21Cip1 up-regulation and JNK. (Q37447640)

20 August 2017

ROCK mediates phorbol ester-induced apoptosis in prostate cancer cells via p21Cip1 up-regulation and JNK. (English)

1 reference

20 August 2017

0 references

1 reference

Masumi Eto

2

0 references

author name string

Liqing Xiao

series ordinal

1

1 reference

20 August 2017

Marcelo G Kazanietz

series ordinal

3

1 reference

20 August 2017

language of work or name

English

0 references

publication date

10 August 2009

1 reference

Journal of Biological Chemistry

20 August 2017

1 reference

20 August 2017

284

1 reference

20 August 2017

43

1 reference

20 August 2017

29365-29375

1 reference

Identification of the Rock-dependent transcriptome in rodent fibroblasts

20 August 2017

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23 August 2017

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Protein kinase C and other diacylglycerol effectors in cancer

23 August 2017

1 reference

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Rho kinase in the regulation of cell death and survival

23 August 2017

1 reference

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Catching a GEF by its tail

23 August 2017

1 reference

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Actin in transcription and transcription regulation.

23 August 2017

1 reference

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RhoA signaling in phorbol ester-induced apoptosis

23 August 2017

1 reference

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Vav3, a Rho GTPase guanine nucleotide exchange factor, increases during progression to androgen independence in prostate cancer cells and potentiates androgen receptor transcriptional activity

23 August 2017

1 reference

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Rho GTPases: biochemistry and biology

23 August 2017

1 reference

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Down-regulation of ATM protein sensitizes human prostate cancer cells to radiation-induced apoptosis

23 August 2017

1 reference

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Sp1: regulation of gene expression by phosphorylation

23 August 2017

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Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK

23 August 2017

1 reference

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Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells

23 August 2017

1 reference

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Rocks: multifunctional kinases in cell behaviour

23 August 2017

1 reference

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Rho GTPases in cell biology

23 August 2017

1 reference

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Cytosolic retention of phosphorylated extracellular signal-regulated kinase and a Rho-associated kinase-mediated signal impair expression of p21(Cip1/Waf1) in phorbol 12-myristate-13- acetate-induced apoptotic cells

23 August 2017

1 reference

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Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions

23 August 2017

1 reference

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Cyclin A-CDK phosphorylates Sp1 and enhances Sp1-mediated transcription

23 August 2017

1 reference

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Protein kinase C isozymes, novel phorbol ester receptors and cancer chemotherapy

23 August 2017

1 reference

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Myosin ii light chain phosphorylation regulates membrane localization and apoptotic signaling of tumor necrosis factor receptor-1

23 August 2017

1 reference

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Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing

23 August 2017

1 reference

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Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.

23 August 2017

1 reference

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Regulation of gene expression by the small GTPase Rho through the ERK6 (p38 gamma) MAP kinase pathway.

23 August 2017

1 reference

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p53-independent elevation of p21 expression by PMA results from PKC-mediated mRNA stabilization

23 August 2017

1 reference

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Protein kinase C-mediated regulation of the cell cycle

23 August 2017

1 reference

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Apoptotic Membrane Blebbing Is Regulated by Myosin Light Chain Phosphorylation

23 August 2017

1 reference

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WAF1, a potential mediator of p53 tumor suppression

23 August 2017

1 reference

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PKC-mediated secretion of death factors in LNCaP prostate cancer cells is regulated by androgens

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

Rho/ROCK/actin signaling regulates membrane androgen receptor induced apoptosis in prostate cancer cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

Phorbol 12-myristate 13-acetate inhibits FRO anaplastic human thyroid cancer cell proliferation by inducing cell cycle arrest in G1/S phase: evidence for an effect mediated by PKCdelta

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

Histone deacetylase inhibitors enhance lexatumumab-induced apoptosis via a p21Cip1-dependent decrease in survivin levels

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

The Rho GTPase effector ROCK regulates cyclin A, cyclin D1, and p27Kip1 levels by distinct mechanisms

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

Contribution of guanine exchange factor H1 in phorbol ester-induced apoptosis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

Phorbol ester-induced apoptosis in prostate cancer cells via autocrine activation of the extrinsic apoptotic cascade: a key role for protein kinase C delta

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

Bortezomib abolishes tumor necrosis factor-related apoptosis-inducing ligand resistance via a p21-dependent mechanism in human bladder and prostate cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

Phorbol ester-induced apoptosis of C4-2 cells requires both a unique and a redundant protein kinase C signaling pathway.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

The small GTP-binding protein RhoA regulates c-jun by a ROCK-JNK signaling axis.

14 September 2017

1 reference

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Transcriptional activation of p21(waf1/cip1) by alkylphospholipids: role of the mitogen-activated protein kinase pathway in the transactivation of the human p21(waf1/cip1) promoter by Sp1.

14 September 2017

1 reference

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Permissive role of protein kinase C alpha but not protein kinase C delta in sphingosine 1-phosphate-induced Rho A activation in C2C12 myoblasts.

14 September 2017

1 reference

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DAP-kinase participates in TNF-alpha- and Fas-induced apoptosis and its function requires the death domain

28 September 2017

1 reference

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Retinoblastoma Protein-dependent Growth Signal Conflict and Caspase Activity Are Required for Protein Kinase C-signaled Apoptosis of Prostate Epithelial Cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

PKCdelta regulates endothelial basal barrier function through modulation of RhoA GTPase activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

Nuclear efflux of heterogeneous nuclear ribonucleoprotein C1/C2 in apoptotic cells: a novel nuclear export dependent on Rho-associated kinase activation.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

Rho/ROCK pathway contributes to the activation of extracellular signal-regulated kinase/GATA-4 during myocardial cell hypertrophy

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

Activation of protein kinase G Increases the expression of p21CIP1, p27KIP1, and histidine triad protein 1 through Sp1.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

A method for measuring Rho kinase activity in tissues and cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

Tamoxifen-induced activation of p21Waf1/Cip1 gene transcription is mediated by Early Growth Response-1 protein through the JNK and p38 MAP kinase/Elk-1 cascades in MDA-MB-361 breast carcinoma cells.

2 September 2018

1 reference

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RhoA/Rho kinase up-regulate Bax to activate a mitochondrial death pathway and induce cardiomyocyte apoptosis

2 September 2018

1 reference

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Targeted disruption of protein kinase C epsilon reduces cell invasion and motility through inactivation of RhoA and RhoC GTPases in head and neck squamous cell carcinoma

2 September 2018

1 reference

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Stability of p21Waf1/Cip1 CDK inhibitor protein is responsive to RhoA-mediated regulation of the actin cytoskeleton.

2 September 2018

1 reference

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Phorbol ester-induced G1 phase arrest selectively mediated by protein kinase Cdelta-dependent induction of p21.

2 September 2018

1 reference

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Signal-crosstalk between Rho/ROCK and c-Jun NH2-terminal kinase mediates migration of vascular smooth muscle cells stimulated by angiotensin II.

2 September 2018

1 reference

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PKC mediates cyclic stretch-induced cardiac hypertrophy through Rho family GTPases and mitogen-activated protein kinases in cardiomyocytes

2 September 2018

1 reference

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Effects of Ethanol on Protein Kinase C α Activity Induced by Association with Rho GTPases

2 September 2018

1 reference

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Role of protein kinase C and the Sp1-p53 complex in activation of p21(WAF-1) expression by 12-O-tetradecanoylphorbol-13-acetate in human T cells

2 September 2018

1 reference

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Caspase activation during phorbol ester-induced apoptosis requires ROCK-dependent myosin-mediated contraction

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the Akt survival pathway

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

Protein kinase C-alpha signals rho-guanine nucleotide dissociation inhibitor phosphorylation and rho activation and regulates the endothelial cell barrier function

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

Interaction of protein kinase C isozymes with Rho GTPases

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

Involvement of protein kinase C delta (PKCdelta) in phorbol ester-induced apoptosis in LNCaP prostate cancer cells. Lack of proteolytic cleavage of PKCdelta

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785568

Determination of GTP loading on Rho

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074/JBC.M109.007971

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074/JBC.M109.007971

Rho kinase regulates phagocytosis, surface expression of GlcNAc, and Golgi fragmentation of apoptotic PC12 cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19667069

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Involvement of a Rho-ROCK-JNK pathway in arsenic trioxide-induced apoptosis in chronic myelogenous leukemia cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19667069

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.007971

1 reference

20 August 2017

1 reference

20 August 2017

PubMed publication ID

19667069

1 reference