NOTCH inhibition and glucocorticoid therapy in T-cell acute lymphoblastic leukemia. (Q37439353)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19357700 AND SRC:MED&resulttype=core&format=json

25 January 2020

review article

1 reference

title

NOTCH inhibition and glucocorticoid therapy in T-cell acute lymphoblastic leukemia (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19357700 AND SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19357700 AND SRC:MED&resulttype=core&format=json

25 January 2020

author name string

A A Ferrando

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19357700 AND SRC:MED&resulttype=core&format=json

25 January 2020

publication date

9 April 2009

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19357700 AND SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19357700 AND SRC:MED&resulttype=core&format=json

25 January 2020

volume

23

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19357700 AND SRC:MED&resulttype=core&format=json

25 January 2020

issue

8

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19357700 AND SRC:MED&resulttype=core&format=json

25 January 2020

page(s)

1374-1377

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19357700 AND SRC:MED&resulttype=core&format=json

Angiogenesis: a team effort coordinated by notch.

25 January 2020

cites work

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Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

23 August 2017

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Adipsin, a biomarker of gastrointestinal toxicity mediated by a functional gamma-secretase inhibitor

23 August 2017

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Molecular determinants of glucocorticoid sensitivity and resistance in acute lymphoblastic leukemia

23 August 2017

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The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon.

23 August 2017

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Improved outcome for children with acute lymphoblastic leukemia: results of Dana-Farber Consortium Protocol 91-01.

23 August 2017

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Clinical implications of recurring chromosomal and associated molecular abnormalities in acute lymphoblastic leukemia

23 August 2017

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A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

23 August 2017

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Improved outcome in childhood acute lymphoblastic leukemia despite reduced use of anthracyclines and cranial radiotherapy: results of trial ALL-BFM 90. German-Austrian-Swiss ALL-BFM Study Group

23 August 2017

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Correlating notch signaling with thymocyte maturation

23 August 2017

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Activation of Notch signaling in tumorigenesis of experimental pancreatic cancer induced by dimethylbenzanthracene in mice

23 August 2017

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Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis

14 September 2017

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Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis

14 September 2017

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14 September 2017

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14 September 2017

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Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation

14 September 2017

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Three mechanisms are involved in glucocorticoid receptor autoregulation in a human T-lymphoblast cell line

14 September 2017

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Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation

14 September 2017

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Chronic treatment with the gamma-secretase inhibitor LY-411,575 inhibits beta-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation

14 September 2017

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Quantification and glucocorticoid regulation of glucocorticoid receptor transcripts in two human leukemic cell lines

14 September 2017

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Glucocorticoid resistance in childhood leukemia

14 September 2017

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Glucocorticoid-induced glucocorticoid-receptor expression and promoter usage is not linked to glucocorticoid resistance in childhood ALL.

14 September 2017

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Glucocorticoid-induced cell death requires autoinduction of glucocorticoid receptor expression in human leukemic T cells

26 June 2018

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Glucocorticoid receptors in chronic lymphocytic leukemia.

26 June 2018

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Positive regulation of the glucocorticoid receptor in human T-cells sensitive to the cytolytic effects of glucocorticoids.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814171

Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo.

26 June 2018

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Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.

2 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814171

Outcome of 609 adults after relapse of acute lymphoblastic leukemia (ALL); an MRC UKALL12/ECOG 2993 study

2 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814171

Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814171

Down-regulation of Notch-1 contributes to cell growth inhibition and apoptosis in pancreatic cancer cells.

2 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814171

Mutations of the Notch1 gene in T-cell acute lymphoblastic leukemia: analysis in adults and children.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814171

Philadelphia chromosome-positive (Ph ) childhood acute lymphoblastic leukemia: good initial steroid response allows early prediction of a favorable treatment outcome.

2 September 2018

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In vitro cellular drug resistance in children with relapsed/refractory acute lymphoblastic leukemia

2 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814171

In vitro drug sensitivity testing can predict induction failure and early relapse of childhood acute lymphoblastic leukemia

2 September 2018

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12 December 2020

Prednisone response is the strongest predictor of treatment outcome in infant acute lymphoblastic leukemia

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12 December 2020

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

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12 December 2020

Acute lymphoblastic leukemia

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12 December 2020

Glucocorticoid receptors in lymphoid tumors

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12 December 2020

Improved outcome in childhood acute lymphoblastic leukaemia with reinforced early treatment and rotational combination chemotherapy

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Intensification of treatment and survival in all children with lymphoblastic leukaemia: results of UK Medical Research Council trial UKALL X. Medical Research Council Working Party on Childhood Leukaemia

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Myeloablative allogeneic versus autologous stem cell transplantation in adult patients with acute lymphoblastic leukemia in first remission: a prospective sibling donor versus no-donor comparison

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Acute lymphoblastic leukemia

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Identifiers

DOI

10.1038/LEU.2009.75

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19357700 AND SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19357700 AND SRC:MED&resulttype=core&format=json

25 January 2020

PubMed publication ID

19357700

1 reference