Blockade of 4-1BB and 4-1BBL interaction reduces obesity-induced skeletal muscle inflammation. (Q37433264)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24453430 AND SRC:MED&resulttype=core&format=json

6 March 2020

title

Blockade of 4-1BB and 4-1BBL interaction reduces obesity-induced skeletal muscle inflammation (English)

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6 March 2020

0 references

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4

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6 March 2020

Tsuyoshi Goto

7

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6 March 2020

6

Teruo Kawada

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6 March 2020

author name string

Ngoc Hoan Le

1

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6 March 2020

Chu-Sook Kim

2

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6 March 2020

Thai Hien Tu

3

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6 March 2020

Byung-Sam Kim

5

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6 March 2020

Taesun Park

8

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6 March 2020

Jung Han Yoon Park

9

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6 March 2020

Rina Yu

10

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6 March 2020

publication date

18 December 2013

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Mediators of Inflammation

6 March 2020

published in

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volume

2013

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6 March 2020

page(s)

865159

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Creative Commons Attribution 3.0 Unported

6 March 2020

copyright license

start time

1 January 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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April 2022 Public Data File from Crossref

describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3880756/fullTextXML

inferred from PubMed Central ID database lookup

cites work

4-1BB/4-1BBL interaction promotes obesity-induced adipose inflammation by triggering bidirectional inflammatory signaling in adipocytes/macrophages.

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Deficiency for Costimulatory Receptor 4-1BB Protects Against Obesity-Induced Inflammation and Metabolic Disorders

23 August 2017

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Acute skeletal muscle injury: CCL2 expression by both monocytes and injured muscle is required for repair

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Toll-like receptor 4 modulates skeletal muscle substrate metabolism

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Blockade of CD137 signaling counteracts polymicrobial sepsis induced by cecal ligation and puncture

23 August 2017

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Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals

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TNF-alpha downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents

23 August 2017

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MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

23 August 2017

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TNF-alpha acts via p38 MAPK to stimulate expression of the ubiquitin ligase atrogin1/MAFbx in skeletal muscle

23 August 2017

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Biological activities of reverse signal transduction through CD137 ligand

23 August 2017

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4-1BB costimulatory signals preferentially induce CD8 T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses

23 August 2017

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Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy

23 August 2017

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TNF-alpha-mediated reduction in PGC-1alpha may impair skeletal muscle function after cigarette smoke exposure

23 August 2017

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Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance

14 September 2017

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Neutralizing anti-4-1BBL treatment improves cardiac function in viral myocarditis

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Palmitate induces tumor necrosis factor-alpha expression in C2C12 skeletal muscle cells by a mechanism involving protein kinase C and nuclear factor-kappaB activation

14 September 2017

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CD137 (4-1BB) deficiency reduces atherosclerosis in hyperlipidemic mice.

26 June 2018

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Attenuation of experimental autoimmune myocarditis by blocking T cell activation through 4-1BB pathway

2 September 2018

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2 September 2018

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2 September 2018

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2 September 2018

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2 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24453430

12 December 2020

inferred from PubMed ID database lookup

4-1BB engagement costimulates NKT cell activation and exacerbates NKT cell ligand-induced airway hyperresponsiveness and inflammation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24453430

12 December 2020

inferred from PubMed ID database lookup

CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24453430

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1155/2013/865159

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24453430 AND SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24453430 AND SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

24453430

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24453430 AND SRC:MED&resulttype=core&format=json