A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta. (Q37425442)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19854138 AND SRC:MED&resulttype=core&format=json

10 February 2020

title

A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta (English)

1 reference

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10 February 2020

3

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10 February 2020

Zhijian Chen

series ordinal

4

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10 February 2020

author name string

Ming Xu

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19854138 AND SRC:MED&resulttype=core&format=json

10 February 2020

Brian Skaug

series ordinal

2

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10 February 2020

publication date

1 October 2009

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10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19854138 AND SRC:MED&resulttype=core&format=json

10 February 2020

volume

36

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10 February 2020

issue

2

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10 February 2020

page(s)

302-314

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NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain

10 February 2020

cites work

1 reference

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Direct activation of protein kinases by unanchored polyubiquitin chains

23 August 2017

1 reference

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Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779160

Nonproteolytic functions of ubiquitin in cell signaling

23 August 2017

1 reference

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Structural Basis for Recognition of Diubiquitins by NEMO

23 August 2017

1 reference

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Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

23 August 2017

1 reference

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Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.

23 August 2017

1 reference

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Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies

23 August 2017

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Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation

23 August 2017

1 reference

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c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation

23 August 2017

1 reference

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cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

23 August 2017

1 reference

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TNF-alpha induces two distinct caspase-8 activation pathways

23 August 2017

1 reference

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IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

23 August 2017

1 reference

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Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779160

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

23 August 2017

1 reference

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Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

23 August 2017

1 reference

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An RNA interference screen identifies Inhibitor of Apoptosis Protein 2 as a regulator of innate immune signalling in Drosophila.

23 August 2017

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Inhibitor of apoptosis 2 and TAK1-binding protein are components of the Drosophila Imd pathway

23 August 2017

1 reference

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Ubiquitin signalling in the NF-kappaB pathway

23 August 2017

1 reference

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Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

23 August 2017

1 reference

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A pervasive role of ubiquitin conjugation in activation and termination of IkappaB kinase pathways

23 August 2017

1 reference

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The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779160

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779160

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779160

The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes

23 August 2017

1 reference

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Back to the future with ubiquitin

23 August 2017

1 reference

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The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

23 August 2017

1 reference

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Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

23 August 2017

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CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

23 August 2017

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TAK1 is a ubiquitin-dependent kinase of MKK and IKK

23 August 2017

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Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer

23 August 2017

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Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

23 August 2017

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Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

23 August 2017

1 reference

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The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

23 August 2017

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23 August 2017

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Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

23 August 2017

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The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses

23 August 2017

1 reference

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A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

23 August 2017

1 reference

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Ubiquitin: Roles in protein modification and breakdown

23 August 2017

1 reference

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RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis

14 September 2017

1 reference

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Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling

28 September 2017

1 reference

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The role of ubiquitination in Drosophila innate immunity.

2 September 2018

1 reference

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Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

2 September 2018

1 reference

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Ubiquitination of RIP Is Required for Tumor Necrosis Factor α-induced NF-κB Activation

3 December 2018

1 reference

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NF-kappaB activation: Nondegradative ubiquitination implicates NEMO

3 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19854138

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cutting Edge: Pivotal function of Ubc13 in thymocyte TCR signaling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19854138

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLCEL.2009.10.002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19854138 AND SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19854138 AND SRC:MED&resulttype=core&format=json

10 February 2020

PubMed publication ID

19854138

1 reference