p27 Is a critical prognostic biomarker in non-alcoholic steatohepatitis-related hepatocellular carcinoma (Q37420848)

20 August 2017

p27 Is a critical prognostic biomarker in non-alcoholic steatohepatitis-related hepatocellular carcinoma (English)

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non-alcoholic steatohepatitis

20 August 2017

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0 references

1 reference

Yasunobu Matsuda

1

1 reference

20 August 2017

Toshifumi Wakai

2

1 reference

20 August 2017

Yuki Hirose

3

1 reference

20 August 2017

Mami Osawa

4

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20 August 2017

Shun Fujimaki

5

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20 August 2017

Masayuki Kubota

6

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20 August 2017

language of work or name

English

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publication date

29 November 2013

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International Journal of Molecular Sciences

20 August 2017

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20 August 2017

14

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20 August 2017

12

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20 August 2017

23499-23515

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Creative Commons Attribution 4.0 International

20 August 2017

start time

29 November 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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23 August 2017

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23 August 2017

Hepatocellular carcinoma

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Hepatocellular carcinoma and liver transplantation: clinical perspective on molecular targeted strategies

23 August 2017

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p27: a barometer of signaling deregulation and potential predictor of response to targeted therapies.

23 August 2017

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Adiponectin antagonizes the oncogenic actions of leptin in hepatocellular carcinogenesis

23 August 2017

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Prevalence, gender, ethnic variations, and prognosis of NASH

23 August 2017

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Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection

23 August 2017

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The incidence and risk factors of hepatocellular carcinoma in patients with nonalcoholic steatohepatitis

23 August 2017

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Nonalcoholic fatty liver disease: a review and update

23 August 2017

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The identification of stem cells in human liver diseases and hepatocellular carcinoma

23 August 2017

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Post-translational regulation of the tumor suppressor p27(KIP1).

23 August 2017

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Molecular mechanism underlying the functional loss of cyclindependent kinase inhibitors p16 and p27 in hepatocellular carcinoma

23 August 2017

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Long-term outcomes of hepatectomy vs percutaneous ablation for treatment of hepatocellular carcinoma < or =4 cm

23 August 2017

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Design and validation of a histological scoring system for nonalcoholic fatty liver disease

23 August 2017

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Expression and altered subcellular localization of the cyclin-dependent kinase inhibitor p27Kip1 in hepatocellular carcinoma

23 August 2017

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Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions

23 August 2017

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Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

23 August 2017

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A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression

23 August 2017

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The prognostic molecular markers in hepatocellular carcinoma

23 August 2017

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p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis

23 August 2017

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High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers

23 August 2017

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Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

23 August 2017

1 reference

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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

23 August 2017

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The cellular basis of site-specific tumor metastasis

23 August 2017

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Activation of LKB1-Akt pathway independent of phosphoinositide 3-kinase plays a critical role in the proliferation of hepatocellular carcinoma from nonalcoholic steatohepatitis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876059

Steatohepatitic hepatocellular carcinoma (SH-HCC): a distinctive histological variant of HCC in hepatitis C virus-related cirrhosis with associated NAFLD/NASH.

14 September 2017

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Expression of Jun activation domain-binding protein 1 and Ser10 phosphorylated p27 protein in human epithelial ovarian carcinoma

14 September 2017

1 reference

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Loss of p16 contributes to p27 sequestration by cyclin D(1)-cyclin-dependent kinase 4 complexes and poor prognosis in hepatocellular carcinoma.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876059

Deregulated expression of p27(Kip1) in human breast cancers.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876059

Increased hepatic oxidative DNA damage in patients with nonalcoholic steatohepatitis who develop hepatocellular carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876059

Outcomes of curative treatment for hepatocellular cancer in nonalcoholic steatohepatitis versus hepatitis C and alcoholic liver disease

2 September 2018

1 reference

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Potential role of Jun activation domain-binding protein 1 and phosphorylated p27 expression in prognosis of glioma

2 September 2018

1 reference

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Decreased immunoexpression of survivin could be a potential marker in human non-alcoholic fatty liver disease progression?

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876059

Phosphorylated p27Kip1 on Thr157 is an important prognosis in human hepatocellular carcinoma in vivo and in vitro.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876059

Visceral fat accumulation is an independent risk factor for hepatocellular carcinoma recurrence after curative treatment in patients with suspected NASH.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876059

p27(Kip1)is overexpressed in very early stages of hepatocarcinogenesis.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876059

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876059

Role of serine 10 phosphorylation in p27 stabilization revealed by analysis of p27 knock-in mice harboring a serine 10 mutation

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876059

Long-term outcomes of cirrhosis in nonalcoholic steatohepatitis compared with hepatitis C.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876059

Acquired expression of p27 is a favorable prognostic indicator in patients with hepatocellular carcinoma

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876059

Expression and prognostic roles of the G1-S modulators in hepatocellular carcinoma: p27 independently predicts the recurrence

2 October 2018

1 reference

12 December 2020

Immunohistochemical expression of components of the Akt-mTORC1 pathway is associated with hepatocellular carcinoma in patients with chronic liver disease

1 reference

12 December 2020

Prospective study of hepatocellular carcinoma in nonalcoholic steatohepatitis in comparison with hepatocellular carcinoma caused by chronic hepatitis C

1 reference

12 December 2020

Surgical outcomes for hepatocellular carcinoma in nonalcoholic fatty liver disease

1 reference

12 December 2020

The diagnosis and management of non-alcoholic fatty liver disease: Practice guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association

1 reference

12 December 2020

Decreased expression of p27 protein is associated with advanced tumor stage in hepatocellular carcinoma

1 reference

12 December 2020

The general rules for the clinical and pathological study of primary liver cancer. Liver Cancer Study Group of Japan

1 reference

12 December 2020

Reduced p27Kip1 expression in hepatocellular carcinomas

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS141223499

1 reference

20 August 2017

1 reference

20 August 2017

PubMed publication ID

24351862

1 reference