Elicitation of broadly reactive antibodies against glycan-modulated neutralizing V3 epitopes of HIV-1 by immune complex vaccines. (Q37419234)

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22 February 2020

title

Elicitation of broadly reactive antibodies against glycan-modulated neutralizing V3 epitopes of HIV-1 by immune complex vaccines (English)

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22 February 2020

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6

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22 February 2020

author name string

Rajnish Kumar

1

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22 February 2020

Michael Tuen

2

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22 February 2020

Jianping Liu

3

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22 February 2020

Arthur Nàdas

4

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22 February 2020

Ruimin Pan

5

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22 February 2020

Catarina E Hioe

7

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22 February 2020

language of work or name

English

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publication date

16 September 2013

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22 February 2020

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22 February 2020

volume

31

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22 February 2020

issue

46

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22 February 2020

page(s)

5413-5421

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Evolution of cross-neutralizing antibody specificities to the CD4-BS and the carbohydrate cloak of the HIV Env in an HIV-1-infected subject

22 February 2020

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Replicating adenovirus-simian immunodeficiency virus (SIV) recombinant priming and envelope protein boosting elicits localized, mucosal IgA immunity in rhesus macaques correlated with delayed acquisition following a repeated low-dose rectal SIV(mac2

23 August 2017

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Intraprotomer masking of third variable loop (V3) epitopes by the first and second variable loops (V1V2) within the native HIV-1 envelope glycoprotein trimer

23 August 2017

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A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

23 August 2017

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HIV-1N-Glycan Composition Governs a Balance between Dendritic Cell-Mediated Viral Transmission and Antigen Presentation

23 August 2017

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Improving immunogenicity of HIV-1 envelope gp120 by glycan removal and immune complex formation

23 August 2017

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Cross-clade HIV-1 neutralizing antibodies induced with V3-scaffold protein immunogens following priming with gp120 DNA.

23 August 2017

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Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure

23 August 2017

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Antibody 2G12 Recognizes Di-Mannose Equivalently in Domain- and Nondomain-Exchanged Forms but Only Binds the HIV-1 Glycan Shield if Domain Exchanged

23 August 2017

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Variable loop glycan dependency of the broad and potent HIV-1-neutralizing antibodies PG9 and PG16.

23 August 2017

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Structure-guided design and immunological characterization of immunogens presenting the HIV-1 gp120 V3 loop on a CTB scaffold.

23 August 2017

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Conserved structural elements in the V3 crown of HIV-1 gp120

23 August 2017

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Anti-V3 monoclonal antibodies display broad neutralizing activities against multiple HIV-1 subtypes

23 August 2017

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Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies

23 August 2017

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The use of immune complex vaccines to enhance antibody responses against neutralizing epitopes on HIV-1 envelope gp120.

23 August 2017

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Proximal glycans outside of the epitopes regulate the presentation of HIV-1 envelope gp120 helper epitopes

23 August 2017

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Preclinical studies of human immunodeficiency virus/AIDS vaccines: inverse correlation between avidity of anti-Env antibodies and peak postchallenge viremia.

23 August 2017

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A randomized controlled phase IIb trial of antigen-antibody immunogenic complex therapeutic vaccine in chronic hepatitis B patients

23 August 2017

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Utilization of Fc receptors as a mucosal vaccine strategy against an intracellular bacterium, Francisella tularensis

23 August 2017

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In vivo alteration of humoral responses to HIV-1 envelope glycoprotein gp120 by antibodies to the CD4-binding site of gp120.

23 August 2017

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Removal of a single N-linked glycan in human immunodeficiency virus type 1 gp120 results in an enhanced ability to induce neutralizing antibody responses

23 August 2017

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Factors determining the breadth and potency of neutralization by V3-specific human monoclonal antibodies derived from subjects infected with clade A or clade B strains of human immunodeficiency virus type 1

23 August 2017

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Delayed vaccine virus replication in chickens vaccinated subcutaneously with an immune complex infectious bursal disease vaccine: quantification of vaccine virus by real-time polymerase chain reaction.

23 August 2017

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Passive immunotherapy in simian immunodeficiency virus-infected macaques accelerates the development of neutralizing antibodies

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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Resistance to V3-directed neutralization caused by an N-linked oligosaccharide depends on the quaternary structure of the HIV-1 envelope oligomer

23 August 2017

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Cryptic nature of envelope V3 region epitopes protects primary monocytotropic human immunodeficiency virus type 1 from antibody neutralization

23 August 2017

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23 August 2017

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Loss of N-linked glycans in the V3-loop region of gp120 is correlated to an enhanced infectivity of HIV-1.

6 September 2017

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Role of complex carbohydrates in human immunodeficiency virus type 1 infection and resistance to antibody neutralization

6 September 2017

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Nonneutralizing antibodies to the CD4-binding site on the gp120 subunit of human immunodeficiency virus type 1 do not interfere with the activity of a neutralizing antibody against the same site

14 September 2017

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The N-terminal V3 loop glycan modulates the interaction of clade A and B human immunodeficiency virus type 1 envelopes with CD4 and chemokine receptors

14 September 2017

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Immunotyping of human immunodeficiency virus type 1 (HIV): an approach to immunologic classification of HIV

14 September 2017

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Immune complex-based vaccine for pig protection against parvovirus

14 September 2017

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Quantitative assessment of masking of neutralization epitopes in HIV-1

14 September 2017

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Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection.

26 June 2018

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Solid matrix-antibody-antigen complexes incorporating equine herpesvirus 1 glycoproteins C and D elicit anti-viral immune responses in BALB/c (H-2K(d)) and C3H (H-2K(k)) mice

2 September 2018

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Antigen-antibody immunogenic complex: promising novel vaccines for microbial persistent infections

2 September 2018

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Crossref

https://api.crossref.org/works/10.1016/J.VACCINE.2013.09.010

Characterization of antibodies that inhibit HIV gp120 antigen processing and presentation

7 January 2021

1 reference

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https://api.crossref.org/works/10.1016/J.VACCINE.2013.09.010

Focusing the immune response on the V3 loop, a neutralizing epitope of the HIV-1 gp120 envelope

7 January 2021

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Crossref

https://api.crossref.org/works/10.1016/J.VACCINE.2013.09.010

10.1016/J.VACCINE.2013.09.010

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24051158 AND SRC:MED&resulttype=core&format=json

22 February 2020

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22 February 2020

PubMed publication ID

24051158

1 reference