Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals. (Q37415532)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15044701 AND SRC:MED&resulttype=core&format=json

26 December 2019

title

Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals (English)

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26 December 2019

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1

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26 December 2019

author name string

Dongling Li

series ordinal

2

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26 December 2019

Astar Winoto

series ordinal

3

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26 December 2019

Ellen A Robey

series ordinal

4

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26 December 2019

language of work or name

English

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publication date

25 March 2004

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Proceedings of the National Academy of Sciences of the United States of America

26 December 2019

published in

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26 December 2019

volume

101

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issue

14

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page(s)

4936-4941

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Transcriptional activation of known and novel apoptotic pathways by Nur77 orphan steroid receptor

26 December 2019

cites work

1 reference

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In vitro evidence that cytokine receptor signals are required for differentiation of double positive thymocytes into functionally mature CD8 T cells

6 September 2017

1 reference

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Positive and negative selection of T cells

6 September 2017

1 reference

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T-cell development and the CD4-CD8 lineage decision

6 September 2017

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Induction of CCR7 expression in thymocytes requires both ERK signal and Ca(2 ) signal

6 September 2017

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Presenilin-dependent gamma-secretase activity modulates thymocyte development

6 September 2017

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6 September 2017

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Notch1 regulates maturation of CD4 and CD8 thymocytes by modulating TCR signal strength

6 September 2017

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6 September 2017

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Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes

6 September 2017

1 reference

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The cyclin-dependent kinase Cdk2 regulates thymocyte apoptosis

6 September 2017

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RORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells

6 September 2017

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Correlating notch signaling with thymocyte maturation

6 September 2017

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Schlafen, a new family of growth regulatory genes that affect thymocyte development

6 September 2017

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Cluster analysis and display of genome-wide expression patterns

6 September 2017

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Induction of the early growth response (Egr) family of transcription factors during thymic selection

6 September 2017

1 reference

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Molecular basis for developmental changes in interleukin-2 gene inducibility

6 September 2017

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Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77.

6 September 2017

1 reference

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Signalling downstream of activated mammalian Notch

6 September 2017

1 reference

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The level of CD8 expression can determine the outcome of thymic selection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

Regulation of N-region diversity in antigen receptors through thymocyte differentiation and thymus ontogeny

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

Thymic depletion and peripheral activation of class I major histocompatibility complex-restricted T cells by soluble peptide in T-cell receptor transgenic mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

Expression profiling of a transformed thymocyte cell line undergoing maturation in vitro identifies multiple genes involved in positive selection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

The interferon regulatory transcription factor IRF-1 controls positive and negative selection of CD8 thymocytes.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4 CD8 thymocyte differentiation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

Thymocyte Expression of RAG-1 and RAG-2: Termination by T Cell Receptor Cross-Linking

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

Highly efficient selection of CD4 and CD8 lineage thymocytes supports an instructive model of lineage commitment

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

Specific regulation of fos family transcription factors in thymocytes at two developmental checkpoints

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

An activated form of Notch influences the choice between CD4 and CD8 T cell lineages

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

Gene expression analysis of thymocyte selection in vivo

26 June 2018

1 reference

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GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation

2 September 2018

1 reference

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Characterization of transcriptional regulation during negative selection in vivo

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

Suppressor of cytokine signaling-1 is a critical regulator of interleukin-7-dependent CD8 T cell differentiation.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

Cutting edge: identification of the targets of clonal deletion in an unmanipulated thymus.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

Overexpression of TIAP/m-survivin in thymocytes enhances cell proliferation

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

FADD-deficient T cells exhibit a disaccord in regulation of the cell cycle machinery

2 September 2018

1 reference

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Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

MHC recognition in thymic development: distinct, parallel pathways for survival and lineage commitment.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

The duration of antigen receptor signalling determines CD4 versus CD8 T-cell lineage fate

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

Precocious expression of T cell functional response genes in vivo in primitive thymocytes before T lineage commitment

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

Regulated expression of gp130 and IL-6 receptor alpha chain in T cell maturation and activation.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C. elegans cell fate decision

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

Role of TCR specificity in CD4 versus CD8 lineage commitment.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

Differentiation to T helper cells in the thymus. Gradual acquisition of T helper cell function by CD3 CD4 cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387352

Frequent provirus insertional mutagenesis of Notch1 in thymomas of MMTVD/myc transgenic mice suggests a collaboration of c-myc and Notch1 for oncogenesis

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0401133101

Positive and negative thymic selection in T cell receptor‐transgenic mice correlate with Nur77 mRNA expression

21 January 2018

1 reference

12 December 2020

Activation of Cdk2 is a requirement for antigen-mediated thymic negative selection

1 reference

12 December 2020

CD53, a thymocyte selection marker whose induction requires a lower affinity TCR-MHC interaction than CD69, but is up-regulated with slower kinetics

1 reference

12 December 2020

A reassessment of the effect of activated Notch1 on CD4 and CD8 T cell development

1 reference

12 December 2020

Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice

1 reference

12 December 2020

Spontaneous apoptosis of thymocytes is uncoupled with progression through the cell cycle

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0401133101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15044701 AND SRC:MED&resulttype=core&format=json

26 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15044701 AND SRC:MED&resulttype=core&format=json

26 December 2019

PubMed publication ID

15044701

1 reference