Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cells (Q37408752)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24078693 AND SRC:MED&resulttype=core&format=json

23 February 2020

title

Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cells (English)

1 reference

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23 February 2020

1 reference

1 reference

5

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23 February 2020

author name string

Christina Antonopoulos

1

1 reference

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23 February 2020

Caroline El Sanadi

2

1 reference

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23 February 2020

William J Kaiser

3

1 reference

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23 February 2020

Edward S Mocarski

4

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23 February 2020

language of work or name

English

0 references

publication date

27 September 2013

1 reference

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23 February 2020

published in

Journal of Immunology

1 reference

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23 February 2020

volume

191

1 reference

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23 February 2020

issue

9

1 reference

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23 February 2020

page(s)

4789-4803

1 reference

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K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter

23 February 2020

cites work

1 reference

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AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC.

6 September 2017

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Deubiquitinases regulate the activity of caspase-1 and interleukin-1β secretion via assembly of the inflammasome

6 September 2017

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Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

6 September 2017

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Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models

6 September 2017

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Immunogenic cell death in cancer therapy

6 September 2017

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Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation

6 September 2017

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TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria

6 September 2017

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Novel role of PKR in inflammasome activation and HMGB1 release

6 September 2017

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Survival function of the FADD-CASPASE-8-cFLIP(L) complex

6 September 2017

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Doxil® — The first FDA-approved nano-drug: Lessons learned

6 September 2017

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Inflammasomes in carcinogenesis and anticancer immune responses

6 September 2017

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Regulation of inflammasome signaling

6 September 2017

1 reference

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Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis

6 September 2017

1 reference

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Targeting IAP proteins for therapeutic intervention in cancer

6 September 2017

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Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome

6 September 2017

1 reference

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Microbial translocation across the GI tract

6 September 2017

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Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways

6 September 2017

1 reference

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Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway

6 September 2017

1 reference

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Non-canonical inflammasome activation targets caspase-11

6 September 2017

1 reference

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cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

6 September 2017

1 reference

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Doxorubicin and daunorubicin induce processing and release of interleukin-1β through activation of the NLRP3 inflammasome

6 September 2017

1 reference

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Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

6 September 2017

1 reference

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RIP3 mediates the embryonic lethality of caspase-8-deficient mice

6 September 2017

1 reference

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Advances in nano drugs for cancer chemotherapy.

6 September 2017

1 reference

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PUMA induction by FoxO3a mediates the anticancer activities of the broad-range kinase inhibitor UCN-01.

6 September 2017

1 reference

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Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia

6 September 2017

1 reference

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HMGB1 release and redox regulates autophagy and apoptosis in cancer cells

6 September 2017

1 reference

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The role of intestinal microbiota in the development and severity of chemotherapy-induced mucositis

6 September 2017

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6 September 2017

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Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors

6 September 2017

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Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

6 September 2017

1 reference

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Cell cycle kinases as therapeutic targets for cancer

6 September 2017

1 reference

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Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling

6 September 2017

1 reference

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P2X7 receptor-stimulated secretion of MHC class II-containing exosomes requires the ASC/NLRP3 inflammasome but is independent of caspase-1.

6 September 2017

1 reference

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P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage

6 September 2017

1 reference

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The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy

6 September 2017

1 reference

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Phase I and pharmacokinetic study of UCN-01 in combination with irinotecan in patients with solid tumors

6 September 2017

1 reference

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Cryopyrin activates the inflammasome in response to toxins and ATP

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3870469

Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death

6 September 2017

1 reference

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Inhibitory effects of chloride on the activation of caspase-1, IL-1beta secretion, and cytolysis by the P2X7 receptor

6 September 2017

1 reference

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Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif

6 September 2017

1 reference

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Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity

6 September 2017

1 reference

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Staurosporine analogues - pharmacological toys or useful antitumour agents?

6 September 2017

1 reference

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Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3870469

The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs

6 September 2017

1 reference

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Triggering of a novel intrinsic apoptosis pathway by the kinase inhibitor staurosporine: activation of caspase-9 in the absence of Apaf-1.

6 September 2017

1 reference

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Immunogenic death of colon cancer cells treated with oxaliplatin

6 September 2017

1 reference

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Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8.

14 September 2017

1 reference

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Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner

14 September 2017

1 reference

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AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella-infected caspase-1-deficient macrophages.

26 June 2018

1 reference

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Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity

26 June 2018

1 reference

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Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome.

26 June 2018

1 reference

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Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity.

2 September 2018

1 reference

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Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

2 September 2018

1 reference

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Phase I trial of 7-hydroxystaurosporine and fludararbine phosphate: in vivo evidence of 7-hydroxystaurosporine induced apoptosis in chronic lymphocytic leukemia.

2 September 2018

1 reference

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Inhibition of the NF-kappaB survival pathway via caspase-dependent cleavage of the IKK complex scaffold protein and NF-kappaB essential modulator NEMO.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3870469

Apoptosis by pan-caspase inhibitors in lipopolysaccharide-activated macrophages

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3870469

Cellular Inhibitors of Apoptosis Proteins cIAP1 and cIAP2 Are Required for Efficient Caspase-1 Activation by the Inflammasome

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24078693

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fas-mediated inflammatory response in Listeria monocytogenes infection

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24078693

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dynamic imaging of T cell-dendritic cell interactions in lymph nodes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24078693

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4049/JIMMUNOL.1300645

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24078693 AND SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24078693 AND SRC:MED&resulttype=core&format=json

23 February 2020

PubMed publication ID

24078693

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24078693 AND SRC:MED&resulttype=core&format=json