Lupeol, a novel anti-inflammatory and anti-cancer dietary triterpene. (Q37394206)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19464787 AND SRC:MED&resulttype=core&format=json

28 January 2020

review article

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title

Lupeol, a novel anti-inflammatory and anti-cancer dietary triterpene (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19464787 AND SRC:MED&resulttype=core&format=json

28 January 2020

0 references

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19464787 AND SRC:MED&resulttype=core&format=json

28 January 2020

author name string

Mohammad Saleem

series ordinal

1

1 reference

20 August 2017

language of work or name

English

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publication date

22 May 2009

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19464787 AND SRC:MED&resulttype=core&format=json

28 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19464787 AND SRC:MED&resulttype=core&format=json

28 January 2020

volume

285

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28 January 2020

issue

2

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28 January 2020

page(s)

109-115

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Combination of antiangiogenesis with chemotherapy for more effective cancer treatment

28 January 2020

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Modulatory effect of Byrsonima basiloba extracts on the mutagenicity of certain direct and indirect-acting mutagens in Salmonella typhimurium assays

6 September 2017

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Protective effects of lupeol and mango extract against androgen induced oxidative stress in Swiss albino mice

6 September 2017

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6 September 2017

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Determination of three major triterpenoids in epicuticular wax of cabbage (Brassica oleracea L.) by high-performance liquid chromatography with UV and mass spectrometric detection

6 September 2017

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Preventive effects of lupeol on DMBA induced DNA alkylation damage in mouse skin

6 September 2017

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6 September 2017

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Phytosterols as anticancer compounds

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Inhibition of multidrug resistance of cancer cells by natural diterpenes, triterpenes and carotenoids.

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Aminopeptidase-N/CD13 (EC 3.4.11.2) inhibitors: chemistry, biological evaluations, and therapeutic prospects.

6 September 2017

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IKK/NF-kappaB signaling: balancing life and death--a new approach to cancer therapy

6 September 2017

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Pentacyclic triterpenoic acids: new chemoprotective compounds. Minireview

6 September 2017

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Lupeol modulates NF-kappaB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice.

6 September 2017

1 reference

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Antitumor activity of bruceantin: an old drug with new promise

6 September 2017

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Plant-derived triterpenoids as potential antineoplastic agents

6 September 2017

1 reference

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Phytosterols, phytostanols, and their conjugates in foods: structural diversity, quantitative analysis, and health-promoting uses.

6 September 2017

1 reference

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Ursolic acid: an anti-tumorigenic and chemopreventive activity. Minireview

6 September 2017

1 reference

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Anti-inflammatory effect of Pimenta racemosa var. ozua and isolation of the triterpene lupeol

6 September 2017

1 reference

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6 September 2017

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A novel derivative pentacyclic triterpene and omega 3 fatty acid

6 September 2017

1 reference

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6 September 2017

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Liquorice and its health implications

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Anti-inflammatory triterpenoids from mysterious mushroom Ganoderma lucidum and their potential possibility in modern medicine.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

The role of genomic instability in human carcinogenesis

6 September 2017

1 reference

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Chemoprevention of cancer

6 September 2017

1 reference

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Mutations and altered expression of the human cancer genes: what they tell us about causes

6 September 2017

1 reference

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Lupeol, a dietary triterpene, inhibited growth, and induced apoptosis through down-regulation of DR3 in SMMC7721 cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Suppression of cFLIP by lupeol, a dietary triterpene, is sufficient to overcome resistance to TRAIL-mediated apoptosis in chemoresistant human pancreatic cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Regulation of signaling pathways involved in lupeol induced inhibition of proliferation and induction of apoptosis in human prostate cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Lupeol inhibits growth of highly aggressive human metastatic melanoma cells in vitro and in vivo by inducing apoptosis.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Lupeol suppresses cisplatin-induced nuclear factor-kappaB activation in head and neck squamous cell carcinoma and inhibits local invasion and nodal metastasis in an orthotopic nude mouse model.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

A novel dietary triterpene Lupeol induces fas-mediated apoptotic death of androgen-sensitive prostate cancer cells and inhibits tumor growth in a xenograft model

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Remodeling of actin cytoskeleton in lupeol-induced B16 2F2 cell differentiation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Expression of estrogen receptor alpha gene in breast cancer cells treated with transcription factor decoy is modulated by Bangladeshi natural plant extracts.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Lupeol inhibits proliferation of human prostate cancer cells by targeting beta-catenin signaling

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Characterization of ursolic acid as a lipoxygenase and cyclooxygenase inhibitor using macrophages, platelets and differentiated HL60 leukemic cells

26 June 2018

1 reference

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Anti-oxidative and anti-inflammatory activities of some isolated constituents from the stem bark of Allanblackia monticola Staner L.C (Guttiferae).

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

The triterpenoid lupeol attenuates allergic airway inflammation in a murine model.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Protective effect of lupeol and lupeol linoleate in hypercholesterolemia associated renal damage

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Protective effects of lupeol against benzo[a]pyrene induced clastogenicity in mouse bone marrow cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Synthesis of lupane-type saponins bearing mannosyl and 3,6-branched trimannosyl residues and their evaluation as anticancer agents.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Wound healing activity and docking of glycogen-synthase-kinase-3-beta-protein with isolated triterpenoid lupeol in rats

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Pentacyclic triterpenes with selective bioactivity from Sebastiania adenophora leaves, Euphorbiaceae.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Suppression of T lymphocyte activity by lupeol isolated from Crataeva religiosa.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Lupeol and its ester exhibit protective role against cyclophosphamide-induced cardiac mitochondrial toxicity

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Lupeol, a fruit and vegetable based triterpene, induces apoptotic death of human pancreatic adenocarcinoma cells via inhibition of Ras signaling pathway.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Lupeol, a triterpene, prevents free radical mediated macromolecular damage and alleviates benzoyl peroxide induced biochemical alterations in murine skin

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Anti-inflammatory constituents of Mortonia greggii Gray

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Lipoxygenase inhibition by anadanthoflavone, a new flavonoid from the aerial parts of Anadenanthera colubrina

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Induction of apoptosis by lupeol isolated from mokumen (Gossampinus malabarica L. Merr) in human promyelotic leukemia HL-60 cells.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Antiangiogenic activity of lupeol from Bombax ceiba

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Effect of three triterpenoids, lupeol, betulin, and betulinic acid on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Evaluation of the effect of triterpenes on urinary risk factors of stone formation in pyridoxine deficient hyperoxaluric rats

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Phytosterol content in American ginseng seed oil.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

New insights into the mechanism of action of the anti-inflammatory triterpene lupeol.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Effects of antiinflammatory triterpenes isolated from Leptadenia hastata latex on keratinocyte proliferation

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764818

Cytotoxicity of bacteriohopane-32-ol against mouse leukemia L1210 and P388 cells in vitro

2 September 2018

1 reference

12 December 2020

Two triterpenes lupanone and lupeol isolated and identified from Tamarindus indica linn

1 reference

12 December 2020

Protective effect of lupeol and its ester on cardiac abnormalities in experimental hypercholesterolemia

1 reference

12 December 2020

Anti-inflammatory and analgesic activities of the ethanolic extracts from Zanthoxylum riedelianum (Rutaceae) leaves and stem bark

1 reference

12 December 2020

Anticomplement activity of triterpenes from Crataeva nurvala stem bark in adjuvant arthritis in rats

1 reference

12 December 2020

Lupeol ameliorates aflatoxin B1-induced peroxidative hepatic damage in rats

1 reference

12 December 2020

Constituents of Shashen (Adenophora axilliflora)

1 reference

12 December 2020

Aloe vera, hydrocortisone, and sterol influence on wound tensile strength and anti-inflammation

1 reference

12 December 2020

Effect of triterpenes from Crataeva nurvala stem bark on lipid peroxidation in adjuvant induced arthritis in rats

1 reference

12 December 2020

Anti-inflammatory and analgesic activities of the latex containing triterpenes from Himatanthus sucuuba

1 reference

12 December 2020

Triterpenes from the spores of Ganoderma lucidum and their cytotoxicity against meth-A and LLC tumor cells

1 reference

12 December 2020

Triterpene alcohols from the flowers of compositae and their anti-inflammatory effects

1 reference

12 December 2020

10.1016/J.CANLET.2009.04.033

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19464787 AND SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19464787 AND SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

19464787

1 reference