Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus (Q37386626)

20 August 2017

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title

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus (English)

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20 August 2017

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3

Donald E Ingber

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20 August 2017

Ning Wang

1

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20 August 2017

Jessica D Tytell

series ordinal

2

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20 August 2017

publication date

1 January 2009

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Nature Reviews Molecular Cell Biology

20 August 2017

published in

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20 August 2017

volume

10

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20 August 2017

issue

1

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20 August 2017

page(s)

75-82

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Local force and geometry sensing regulate cell functions

20 August 2017

cites work

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Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure

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Rapid signal transduction in living cells is a unique feature of mechanotransduction.

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Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy

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A novel role for the nuclear membrane protein emerin in association of the centrosome to the outer nuclear membrane

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Emerin interacts in vitro with the splicing-associated factor, YT521-B

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Inner nuclear membrane proteins: functions and targeting

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Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness

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Intermediate filaments and stress

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Nuclear lamins, diseases and aging

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Unraveling the organization of the internal nuclear matrix: RNA-dependent anchoring of NuMA to a lamin scaffold

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Identifying functional neighborhoods within the cell nucleus: proximity analysis of early S-phase replicating chromatin domains to sites of transcription, RNA polymerase II, HP1gamma, matrin 3 and SAF-A.

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Nuclear titin interacts with A- and B-type lamins in vitro and in vivo

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The giant protein titin: a major player in myocardial mechanics, signaling, and disease

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As functional nuclear actin comes into view, is it globular, filamentous, or both?

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Nuclear myosin VI enhances RNA polymerase II-dependent transcription

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Nuclear myosin I acts in concert with polymeric actin to drive RNA polymerase I transcription

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Emerin caps the pointed end of actin filaments: evidence for an actin cortical network at the nuclear inner membrane

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Association of emerin with nuclear and cytoplasmic actin is regulated in differentiating myoblasts

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31 March 2020

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31 March 2020

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Organization of transcriptional regulatory machinery in nuclear microenvironments: implications for biological control and cancer

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The dynamic organization of gene-regulatory machinery in nuclear microenvironments

31 March 2020

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Cell spreading controls endoplasmic and nuclear calcium: a physical gene regulation pathway from the cell surface to the nucleus

31 March 2020

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Nuclear ion channel activity is regulated by actin filaments

31 March 2020

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Emerin binding to Btf, a death-promoting transcriptional repressor, is disrupted by a missense mutation that causes Emery-Dreifuss muscular dystrophy

31 March 2020

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In vivo and in vitro interaction between human transcription factor MOK2 and nuclear lamin A/C.

31 March 2020

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Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factors

31 March 2020

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Association of nuclear matrix antigens with exon-containing splicing complexes

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The kinase domain of titin controls muscle gene expression and protein turnover

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The permeability of the nuclear envelope in dividing and nondividing cell cultures

31 March 2020

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Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export

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Role of nuclear size in cell growth initiation

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The FUSE/FBP/FIR/TFIIH system is a molecular machine programming a pulse of c-myc expression

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A multi-modular tensegrity model of an actin stress fiber

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Viscoelastic properties of vimentin compared with other filamentous biopolymer networks

31 March 2020

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Physical plasticity of the nucleus in stem cell differentiation

31 March 2020

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Actin and myosin I in the nucleus: what next?

31 March 2020

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Mechanotransduction in vascular physiology and atherogenesis

31 March 2020

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Neurosensory mechanotransduction

31 March 2020

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Mechanotransduction gone awry

31 March 2020

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Environmental sensing through focal adhesions

31 March 2020

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Altering the cellular mechanical force balance results in integrated changes in cell, cytoskeletal and nuclear shape

31 March 2020

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12 December 2020

Cytoplasmic rheology of passive neutrophils

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12 December 2020

Lamin proteins form an internal nucleoskeleton as well as a peripheral lamina in human cells

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12 December 2020

The architectural organization of nuclear metabolism

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12 December 2020

Distinct functional domains in emerin bind lamin A and DNA-bridging protein BAF

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12 December 2020

unc-83 encodes a novel component of the nuclear envelope and is essential for proper nuclear migration

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12 December 2020

Identifiers

DOI

10.1038/NRM2863

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20 August 2017

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