Essential protective role of tumor necrosis factor receptor 2 in neurodegeneration (Q37379859)

20 August 2017

Essential protective role of tumor necrosis factor receptor 2 in neurodegeneration (English)

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20 August 2017

1 reference

2

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3 June 2020

Ulrich Eisel

14

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3 June 2020

13

Klaus Pfizenmaier

1 reference

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3 June 2020

12

Roland E Kontermann

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3 June 2020

author name string

Yun Dong

1

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3 June 2020

Petrus J W Naudé

3

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3 June 2020

Olaf Maier

4

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3 June 2020

Csaba Nyakas

5

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3 June 2020

Maëlle Duffey

6

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3 June 2020

Eddy A Van der Zee

7

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3 June 2020

Doortje Dekens

8

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3 June 2020

Wanda Douwenga

9

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3 June 2020

Andreas Herrmann

10

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3 June 2020

Eric Guenzi

11

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3 June 2020

language of work or name

English

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publication date

10 October 2016

1 reference

Proceedings of the National Academy of Sciences of the United States of America

20 August 2017

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3 June 2020

volume

113

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3 June 2020

issue

43

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3 June 2020

page(s)

12304-12309

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TNF and its receptors in the CNS: The essential, the desirable and the deleterious effects

3 June 2020

cites work

1 reference

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Interrelation of oxidative stress and inflammation in neurodegenerative disease: role of TNF.

6 September 2017

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Central but not systemic administration of XPro1595 is therapeutic following moderate spinal cord injury in mice

6 September 2017

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Antibody-mediated inhibition of TNFR1 attenuates disease in a mouse model of multiple sclerosis.

6 September 2017

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Astrocyte-specific activation of TNFR2 promotes oligodendrocyte maturation by secretion of leukemia inhibitory factor

6 September 2017

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Antagonistic TNF receptor one-specific antibody (ATROSAB): receptor binding and in vitro bioactivity

6 September 2017

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TNFR2 is critical for the stabilization of the CD4 Foxp3 regulatory T. cell phenotype in the inflammatory environment.

6 September 2017

1 reference

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Astrocyte TNFR2 is required for CXCL12-mediated regulation of oligodendrocyte progenitor proliferation and differentiation within the adult CNS.

6 September 2017

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A TNF receptor 2 selective agonist rescues human neurons from oxidative stress-induced cell death

6 September 2017

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Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination

6 September 2017

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Boosting Brain Uptake of a Therapeutic Antibody by Reducing Its Affinity for a Transcytosis Target

6 September 2017

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A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivo

6 September 2017

1 reference

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KCa2 channels activation prevents [Ca2 ]i deregulation and reduces neuronal death following glutamate toxicity and cerebral ischemia

6 September 2017

1 reference

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TNF-alpha: an activator of CD4 FoxP3 TNFR2 regulatory T cells.

6 September 2017

1 reference

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Co-expression of TNFR2 and CD25 identifies more of the functional CD4 FOXP3 regulatory T cells in human peripheral blood.

6 September 2017

1 reference

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TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease

6 September 2017

1 reference

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Cutting edge: expression of TNFR2 defines a maximally suppressive subset of mouse CD4 CD25 FoxP3 T regulatory cells: applicability to tumor-infiltrating T regulatory cells.

6 September 2017

1 reference

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Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system--too little activation is bad, too much is even worse

6 September 2017

1 reference

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Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury

6 September 2017

1 reference

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CellProfiler: image analysis software for identifying and quantifying cell phenotypes

6 September 2017

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TNF pathophysiology in murine models of chronic inflammation and autoimmunity.

6 September 2017

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Tumor necrosis factor (TNF)-mediated neuroprotection against glutamate-induced excitotoxicity is enhanced by N-methyl-D-aspartate receptor activation. Essential role of a TNF receptor 2-mediated phosphatidylinositol 3-kinase-dependent NF-kappa B pat

6 September 2017

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Signalling pathways of the TNF superfamily: a double-edged sword

6 September 2017

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Brain damage in a mouse model of global cerebral ischemia. Effect of NMDA receptor blockade

6 September 2017

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Tumor necrosis factor signaling.

6 September 2017

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High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells

6 September 2017

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The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

6 September 2017

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Benzodiazepine impairs and beta-carboline enhances performance in learning and memory tasks

6 September 2017

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Expression of costimulatory TNFR2 induces resistance of CD4 FoxP3- conventional T cells to suppression by CD4 FoxP3 regulatory T cells.

6 September 2017

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Homogeneous expansion of human T-regulatory cells via tumor necrosis factor receptor 2

14 September 2017

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ATROSAB, a humanized antagonistic anti-tumor necrosis factor receptor one-specific antibody

26 June 2018

1 reference

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Pretreatment with lovastatin prevents N-methyl-D-aspartate-induced neurodegeneration in the magnocellular nucleus basalis and behavioral dysfunction

26 June 2018

1 reference

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Short-term consequences of N-methyl-D-aspartate excitotoxicity in rat magnocellular nucleus basalis: effects on in vivo labelling of cholinergic neurons

26 June 2018

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beta-amyloid neurotoxicity is mediated by a glutamate-triggered excitotoxic cascade in rat nucleus basalis

26 June 2018

1 reference

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Continuous monitoring and regulating of brain temperature in the conscious and freely moving ischemic gerbil: effect of MK-801 on delayed neuronal death in hippocampal CA1.

26 June 2018

1 reference

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Targeted disruption of the MHC class II Aa gene in C57BL/6 mice

26 June 2018

1 reference

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Cortical projection patterns of the medial septum-diagonal band complex

26 June 2018

1 reference

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Regulation of the intracellular free calcium concentration in single rat dorsal root ganglion neurones in vitro

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5087045

Altered expression of oligodendrocyte and neuronal marker genes predicts the clinical onset of autoimmune encephalomyelitis and indicates the effectiveness of multiple sclerosis-directed therapeutics.

26 June 2018

1 reference

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Tetravalent antibody-scTRAIL fusion proteins with improved properties

2 September 2018

1 reference

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TNF receptor 2 protects oligodendrocyte progenitor cells against oxidative stress

2 September 2018

1 reference

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Transmembrane tumour necrosis factor is neuroprotective and regulates experimental autoimmune encephalomyelitis via neuronal nuclear factor-kappaB.

2 September 2018

1 reference

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Calpain inhibition prevents amyloid-beta-induced neurodegeneration and associated behavioral dysfunction in rats

2 September 2018

1 reference

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TNF-alpha-mediates neuroprotection against glutamate-induced excitotoxicity via NF-kappaB-dependent up-regulation of K2.2 channels

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5087045

Lovastatin induces neuroprotection through tumor necrosis factor receptor 2 signaling pathways.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5087045

Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4 CD25 T regulatory cells.

2 September 2018

1 reference

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TNFalpha transport across the blood-brain barrier is abolished in receptor knockout mice

2 September 2018

1 reference

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Neurodegenerative and neuroprotective effects of tumor Necrosis factor (TNF) in retinal ischemia: opposite roles of TNF receptor 1 and TNF receptor 2.

2 September 2018

1 reference

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TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination

2 September 2018

1 reference

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Neuroprotection against NMDA induced cell death in rat nucleus basalis by Ca2 antagonist nimodipine, influence of aging and developmental drug treatment.

2 September 2018

1 reference

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TR60 and TR80 tumor necrosis factor (TNF)-receptors can independently mediate cytolysis

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5087045

Human tumor necrosis factor alpha (TNF alpha) mutants with exclusive specificity for the 55-kDa or 75-kDa TNF receptors.

2 September 2018

1 reference

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Enhancement of TNF receptor p60-mediated cytotoxicity by TNF receptor p80: requirement of the TNF receptor-associated factor-2 binding site

2 September 2018

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12 December 2020

Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons

1 reference

12 December 2020

Apoptotic crosstalk of TNF receptors: TNF-R2-induces depletion of TRAF2 and IAP proteins and accelerates TNF-R1-dependent activation of caspase-8

1 reference

12 December 2020

TNF neutralization in MS: results of a randomized, placebo-controlled multicenter study. The Lenercept Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1605195113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791020 AND SRC:MED&resulttype=core&format=json

3 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791020 AND SRC:MED&resulttype=core&format=json

3 June 2020

PubMed publication ID

27791020

1 reference