Hedgehog pathway blockade inhibits melanoma cell growth in vitro and in vivo (Q37370438)

20 August 2017

Hedgehog pathway blockade inhibits melanoma cell growth in vitro and in vivo (English)

1 reference

20 August 2017

1 reference

3

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9 June 2020

Erica B Friedman

4

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9 June 2020

Laura Poliseno

5

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9 June 2020

Judy Zhong

7

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9 June 2020

Jiří Zavadil

8

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9 June 2020

Eva Hernando

10

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9 June 2020

author name string

Kathryn E O'Reilly

1

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9 June 2020

Eleazar Vega-Saenz de Miera

2

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9 June 2020

Sung Won Han

6

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9 June 2020

Anna Pavlick

9

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9 June 2020

Iman Osman

11

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9 June 2020

publication date

11 November 2013

1 reference

20 August 2017

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9 June 2020

volume

6

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9 June 2020

issue

11

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9 June 2020

page(s)

1429-1450

1 reference

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Creative Commons Attribution 4.0 International

9 June 2020

copyright license

start time

11 November 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

NVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivo

1 reference

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Hedgehog-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cells

6 September 2017

1 reference

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Phase I study of RO4929097, a gamma secretase inhibitor of Notch signaling, in patients with refractory metastatic or locally advanced solid tumors

6 September 2017

1 reference

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A Notch1-neuregulin1 autocrine signaling loop contributes to melanoma growth

6 September 2017

1 reference

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The novel gamma secretase inhibitor RO4929097 reduces the tumor initiating potential of melanoma

6 September 2017

1 reference

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Hedgehog Fights Back: Mechanisms of Acquired Resistance against Smoothened Antagonists

6 September 2017

1 reference

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Breast cancer growth and metastasis: interplay between cancer stem cells, embryonic signaling pathways and epithelial-to-mesenchymal transition

6 September 2017

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Ipilimumab plus dacarbazine for previously untreated metastatic melanoma

6 September 2017

1 reference

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Improved survival with vemurafenib in melanoma with BRAF V600E mutation

6 September 2017

1 reference

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Hedgehog signaling in skin cancers

6 September 2017

1 reference

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Integrative genomics identifies molecular alterations that challenge the linear model of melanoma progression

6 September 2017

1 reference

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The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance.

6 September 2017

1 reference

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Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways

6 September 2017

1 reference

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GLI2-mediated melanoma invasion and metastasis

6 September 2017

1 reference

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Targeting Hedgehog--a cancer stem cell pathway

6 September 2017

1 reference

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Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

6 September 2017

1 reference

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Small molecule modulation of HH-GLI signaling: current leads, trials and tribulations

6 September 2017

1 reference

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Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3854019

The hedgehog pathway transcription factor GLI1 promotes malignant behavior of cancer cells by up-regulating osteopontin

6 September 2017

1 reference

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Therapeutic potential of gamma-secretase inhibitors and modulators

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3854019

Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.

6 September 2017

1 reference

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Bcl-2 antisense (oblimersen sodium) plus dacarbazine in patients with advanced melanoma: the Oblimersen Melanoma Study Group

6 September 2017

1 reference

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A tumorigenic subpopulation with stem cell properties in melanomas

6 September 2017

1 reference

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Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

6 September 2017

1 reference

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Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

6 September 2017

1 reference

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Small Molecule Inhibition of GDC-0449 Refractory Smoothened Mutants and Downstream Mechanisms of Drug Resistance

6 September 2017

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Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer

14 September 2017

1 reference

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Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

14 September 2017

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Interfering with resistance to smoothened antagonists by inhibition of the PI3K pathway in medulloblastoma.

14 September 2017

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Requirement of Notch activation during regeneration of the intestinal epithelia

2 September 2018

1 reference

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Medulloblastoma growth inhibition by hedgehog pathway blockade

2 September 2018

1 reference

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How melanomas bypass new therapy

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.3390/PH6111429

Time trends of cutaneous melanoma in Queensland, Australia and Central Europe

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24287465

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Targeting the Hedgehog pathway in cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24287465

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3390/PH6111429

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24287465 AND SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24287465 AND SRC:MED&resulttype=core&format=json

9 June 2020

PubMed publication ID

24287465

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24287465 AND SRC:MED&resulttype=core&format=json