Diffuse intrinsic pontine glioma treated with prolonged temozolomide and radiotherapy--results of a United Kingdom phase II trial (CNS 2007 04). (Q37369556)

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scientific article published on 04 September 2013

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English	Diffuse intrinsic pontine glioma treated with prolonged temozolomide and radiotherapy--results of a United Kingdom phase II trial (CNS 2007 04).	scientific article published on 04 September 2013

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scholarly article

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20 August 2017

Diffuse intrinsic pontine glioma treated with prolonged temozolomide and radiotherapy--results of a United Kingdom phase II trial (CNS 2007 04). (English)

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20 August 2017

phase II clinical trial

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diffuse midline glioma

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adaptive radiation therapy

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8

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12 June 2020

Daniel J Connolly

13

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12 June 2020

Darren Hargrave

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12 June 2020

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S Bailey

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12 June 2020

A Howman

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12 June 2020

K Wheatley

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12 June 2020

D Wherton

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12 June 2020

N Boota

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12 June 2020

B Pizer

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12 June 2020

D Fisher

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12 June 2020

S Picton

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12 June 2020

F Saran

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12 June 2020

M Gibson

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12 June 2020

A Glaser

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12 June 2020

publication date

4 September 2013

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European Journal of Cancer

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12 June 2020

49

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12 June 2020

18

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12 June 2020

3856-3862

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12 June 2020

Pediatric diffuse intrinsic pontine glioma: can optimism replace pessimism?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853623

6 September 2017

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853623

6 September 2017

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853623

6 September 2017

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

1 reference

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6 September 2017

Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma

1 reference

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6 September 2017

Radiotherapy with concurrent and adjuvant temozolomide in children with newly diagnosed diffuse intrinsic pontine glioma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853623

6 September 2017

Diffuse intrinsic pontine gliomas: a systematic update on clinical trials and biology.

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6 September 2017

Temozolomide in the treatment of children with newly diagnosed diffuse intrinsic pontine gliomas: a report from the Children's Oncology Group

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6 September 2017

A multi-centre Canadian pilot study of metronomic temozolomide combined with radiotherapy for newly diagnosed paediatric brainstem glioma

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6 September 2017

Outcome and prognostic features in pediatric gliomas: a review of 6212 cases from the Surveillance, Epidemiology, and End Results database

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6 September 2017

Prospective evaluation of radiotherapy with concurrent and adjuvant temozolomide in children with newly diagnosed diffuse intrinsic pontine glioma

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6 September 2017

Predicting the myelotoxicity of chemotherapy: the use of pretreatment O6-methylguanine-DNA methyltransferase determination in peripheral blood mononuclear cells

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6 September 2017

Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853623

6 September 2017

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

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6 September 2017

Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity

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6 September 2017

Safety and pharmacokinetics of temozolomide using a dose-escalation, metronomic schedule in recurrent paediatric brain tumours

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6 September 2017

Diffuse brainstem glioma in children: critical review of clinical trials

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6 September 2017

Design of Phase II cancer trials evaluating survival probabilities

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6 September 2017

Marked inactivation of O6-alkylguanine-DNA alkyltransferase activity with protracted temozolomide schedules

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6 September 2017

The Health Utilities Index (HUI) system for assessing health-related quality of life in clinical studies

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6 September 2017

UKCCSG study of accelerated radiotherapy for pediatric brain stem gliomas. United Kingdom Childhood Cancer Study Group

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6 September 2017

The Strengths and Difficulties Questionnaire: A Research Note

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6 September 2017

Final results of a study of escalating doses of hyperfractionated radiotherapy in brain stem tumors in children: a Pediatric Oncology Group study

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6 September 2017

Pre-irradiation chemotherapy and hyperfractionated radiation therapy 66 Gy for children with brain stem tumors. A phase II study of the Pediatric Oncology Group, Protocol 8833.

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6 September 2017

Preradiation chemotherapy in primary high-risk brainstem tumors: phase II study CCG-9941 of the Children's Cancer Group

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26 June 2018

Carboplatin and etoposide with hyperfractionated radiotherapy in children with newly diagnosed diffuse pontine gliomas: A phase I/II study

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26 June 2018

Brain stem tumors in children: results of a survey of 62 patients treated with radiotherapy

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26 June 2018

Robot-guided convection-enhanced delivery of carboplatin for advanced brainstem glioma

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2 September 2018

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2 September 2018

Temozolomide versus procarbazine, lomustine, and vincristine in recurrent high-grade glioma.

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2 September 2018

Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential therapeutic targets

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2 September 2018

Recurrence pattern after temozolomide concomitant with and adjuvant to radiotherapy in newly diagnosed patients with glioblastoma: correlation With MGMT promoter methylation status

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2 September 2018

Young age may predict a better outcome for children with diffuse pontine glioma.

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2 September 2018

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12 December 2020

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10.1016/J.EJCA.2013.08.006

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12 June 2020

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12 June 2020

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