Functional roles for C5a receptors in sepsis (Q37367089)

20 August 2017

Functional roles for C5a receptors in sepsis (English)

1 reference

20 August 2017

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13

Peter A Ward

1 reference

20 August 2017

5

Markus Huber-Lang

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20 August 2017

1

Daniel Rittirsch

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20 August 2017

7

Firas S Zetoune

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20 August 2017

9

Katherine Cianflone

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20 August 2017

12

J Vidya Sarma

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20 August 2017

2

Michael A Flierl

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20 August 2017

3

Brian A Nadeau

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20 August 2017

Danielle E Day

4

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20 August 2017

Charles R Mackay

6

1 reference

20 August 2017

Norma P Gerard

8

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20 August 2017

Jörg Köhl

10

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20 August 2017

Craig Gerard

11

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20 August 2017

language of work or name

English

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publication date

4 May 2008

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20 August 2017

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20 August 2017

14

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20 August 2017

5

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20 August 2017

551-557

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C5L2--an anti-inflammatory molecule or a receptor for acylation stimulating protein (C3a-desArg)?

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

Ligand specificity of the anaphylatoxin C5L2 receptor and its regulation on myeloid and epithelial cell lines

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

Role of HMGB1 in apoptosis-mediated sepsis lethality

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

The role of complement in danger sensing and transmission

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

An anti-inflammatory function for the complement anaphylatoxin C5a-binding protein, C5L2

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

Complement and Toll-like receptors: key regulators of adaptive immune responses

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

C5L2 is a functional receptor for acylation-stimulating protein

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

Identification of complement 5a-like receptor (C5L2) from astrocytes: characterization of anti-inflammatory properties

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

Changes in the novel orphan, C5a receptor (C5L2), during experimental sepsis and sepsis in humans

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

Reversing established sepsis with antagonists of endogenous high-mobility group box 1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

C5a mutants are potent antagonists of the C5a receptor (CD88) and of C5L2: position 69 is the locus that determines agonism or antagonism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

C5L2, a nonsignaling C5A binding protein

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

The chemoattractant receptor-like protein C5L2 binds the C3a des-Arg77/acylation-stimulating protein

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74)

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

New EMBO members' review: the double life of HMGB1 chromatin protein: architectural factor and extracellular signal

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

A putative chemoattractant receptor, C5L2, is expressed in granulocyte and immature dendritic cells, but not in mature dendritic cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

HMG-1 as a late mediator of endotoxin lethality in mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

Impaired Inflammatory Responses in the Reverse Arthus Reaction Through Genetic Deletion of the C5a Receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

C5A anaphylatoxin and its seven transmembrane-segment receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

The chemotactic receptor for human C5a anaphylatoxin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

Evidence for a functional role of the second C5a receptor C5L2.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

Cutting edge: targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

Anti-high-mobility group box chromosomal protein 1 antibodies improve survival of rats with sepsis.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

C5a negatively regulates toll-like receptor 4-induced immune responses

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

HMGB1 contributes to the development of acute lung injury after hemorrhage

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

Induction of anaphylatoxin C5a receptors in rat hepatocytes by lipopolysaccharide in vivo: mediation by interleukin-6 from Kupffer cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

Protective effects of C5a blockade in sepsis

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753858

High mobility group protein 1 (HMGB1) quantified by ELISA with a monoclonal antibody that does not cross-react with HMGB2

2 September 2018

1 reference

12 December 2020

C5a initiates the inflammatory cascade in immune complex peritonitis

1 reference

12 December 2020

A new biologic role for C3a and C3a desArg: regulation of TNF-alpha and IL-1 beta synthesis

1 reference

12 December 2020

In vitro and in vivo dependency of chemokine generation on C5a and TNF-alpha

1 reference

12 December 2020

Pharmacological targeting of anaphylatoxin receptors during the effector phase of allergic asthma suppresses airway hyperresponsiveness and airway inflammation

1 reference

12 December 2020

Human C5aR knock-in mice facilitate the production and assessment of anti-inflammatory monoclonal antibodies

1 reference

12 December 2020

C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM1753

1 reference

20 August 2017

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20 August 2017

PubMed publication ID

18454156

1 reference