Peripheral subnuclear positioning suppresses Tcrb recombination and segregates Tcrb alleles from RAG2. (Q37353134)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24218622 AND SRC:MED&resulttype=core&format=json

29 February 2020

title

Peripheral subnuclear positioning suppresses Tcrb recombination and segregates Tcrb alleles from RAG2 (English)

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29 February 2020

1

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author name string

Grace Teng

2

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29 February 2020

Elizabeth Corbett

3

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29 February 2020

Kingshuk Roy Choudhury

4

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29 February 2020

Craig H Bassing

5

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29 February 2020

David G Schatz

6

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29 February 2020

Michael S Krangel

7

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29 February 2020

language of work or name

English

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publication date

11 November 2013

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Proceedings of the National Academy of Sciences of the United States of America

29 February 2020

published in

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volume

110

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issue

48

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29 February 2020

page(s)

E4628-37

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describes a project that uses

29 February 2020

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

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Identification of a perinuclear positioning element in human subtelomeres that requires A-type lamins and CTCF.

6 September 2017

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6 September 2017

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6 September 2017

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53BP1 facilitates long-range DNA end-joining during V(D)J recombination

6 September 2017

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Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

6 September 2017

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Recruitment to the nuclear periphery can alter expression of genes in human cells

6 September 2017

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A genetic locus targeted to the nuclear periphery in living cells maintains its transcriptional competence

6 September 2017

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RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination

6 September 2017

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A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement

6 September 2017

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6 September 2017

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6 September 2017

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A PHD finger motif in the C terminus of RAG2 modulates recombination activity

6 September 2017

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6 September 2017

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Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei

6 September 2017

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Rap1 affects the length and heterogeneity of human telomeres

6 September 2017

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Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre

6 September 2017

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Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

Regulation of thymocyte differentiation: pre-TCR signals and beta-selection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

Epitope analysis of antibodies recognising the cell proliferation associated nuclear antigen previously defined by the antibody Ki-67 (Ki-67 protein).

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

Subnuclear segregation of genes and core promoter factors in myogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

In situ visualization of DNA double-strand break repair in human fibroblasts

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

Spatial dynamics of chromosome translocations in living cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

Role of the Nuclear Lamina in Genome Organization and Gene Expression

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

Initiation of allelic exclusion by stochastic interaction of Tcrb alleles with repressive nuclear compartments

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

Productive coupling of accessible Vbeta14 segments and DJbeta complexes determines the frequency of Vbeta14 rearrangement

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

Germline transcription from T-cell receptor Vbeta gene is uncoupled from allelic exclusion

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

Assembled DJ beta complexes influence TCR beta chain selection and peripheral V beta repertoire

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

Transcriptional repression mediated by repositioning of genes to the nuclear lamina

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

Characterization of the Drosophila melanogaster genome at the nuclear lamina.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

Nuclear repositioning marks the selective exclusion of lineage-inappropriate transcription factor loci during T helper cell differentiation

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845165

A change in the structure of Vbeta chromatin associated with TCR beta allelic exclusion

2 September 2018

1 reference

12 December 2020

A conserved degradation signal regulates RAG-2 accumulation during cell division and links V(D)J recombination to the cell cycle

1 reference

12 December 2020

Regulation of T cell receptor beta allelic exclusion at a level beyond accessibility

1 reference

12 December 2020

Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1310846110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24218622 AND SRC:MED&resulttype=core&format=json

29 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24218622 AND SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

24218622

1 reference